{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T23:55:23Z","timestamp":1791590123043,"version":"4.3.4"},"reference-count":41,"publisher":"Georg Thieme Verlag KG","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Zentralbl Chir"],"abstract":"<jats:title>Zusammenfassung<\/jats:title>\n                  <jats:p>F\u00fcr den Vergleich unterschiedlicher Techniken der minimalinvasiven \u00d6sophagektomie sind Real-World-Resultate unselektionierter Serien mit sehr standardisiertem Management wichtig. Daher wird dieses im Detail beschrieben und die entsprechenden Ergebnisse pr\u00e4sentiert.<\/jats:p>\n                  <jats:p>In einer retrospektiven Studie von 193 konsekutiven minimalinvasiven Hybrid-\u00d6sophagektomien (laparoskopisch\/Thorakotomie) inkl. 9 Konversionen (4,6%) und 4 prim\u00e4r offenen \u00d6sophagektomien mit insgesamt 195 Magen- und 2 Koloninterpositionen (196 hoch intrathorakale Anastomosen und 1 zervikale \u00d6sophagogastrostomie) wurden die histopathologischen und klinischen Kurzzeitresultate analysiert. Nur 1 Patient hatte Fernmetastasen (M1HEP) und wurde wegen transfusionspflichtiger Tumorblutung unter Chemotherapie operiert. 78% hatten Adenokarzinome und 20% Plattenepithelkarzinome. 65% der Tumoren waren cT3, 20% cT2, 14% cT1 und 77% der Patient*innen wurden neoadjuvant vorwiegend nach dem FLOT- oder CROSS-Protokoll behandelt inkl. 6 mit definitiver Radiochemotherapie und sp\u00e4terer Salvage-\u00d6sophagektomie.<\/jats:p>\n                  <jats:p>Die R0-Resektionsrate war 99%, im Median wurden 34 Lymphknoten entfernt. Folgende Komplikationen wurden verzeichnet: Anastomoseninsuffizienz 1,5% (n\u00a0=\u00a03), Pneumonie 11%, Chylothorax 1,5%, Nachblutungen 0,5%, Revisionsoperationen 2%. Die 30- bzw. 90-Tage-Mortalit\u00e4t betrug 1,5%, bzw. 4,6%. Einer von 3 Patienten mit Anastomosenleckage verstarb trotz endoskopischer Therapie.<\/jats:p>\n                  <jats:p>Die beschriebene minimalinvasive Hybrid-\u00d6sophagektomie ist ein sicheres Verfahren mit sehr niedriger Rate von Anastomosenleckagen. Diese Benchmark ist wichtig f\u00fcr den Vergleich mit den Resultaten anderer Techniken der minimalinvasiven Ivor-Lewis-\u00d6sophagektomie.<\/jats:p>","DOI":"10.1055\/a-2955-8048","type":"journal-article","created":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T23:40:47Z","timestamp":1791589247000},"source":"Crossref","is-referenced-by-count":0,"title":["Standardisierte minimalinvasive Ivor-Lewis-Hybrid-\u00d6sophagektomie \u2013 sichere Anastomose und niedrige Morbidit\u00e4t\/Mortalit\u00e4t"],"prefix":"10.1055","author":[{"given":"Arnulf H.","family":"H\u00f6lscher","sequence":"additional","affiliation":[{"name":"Elisabeth-Krankenhaus Essen GmbH, Deutschland","place":["Essen"],"department":["Contilia Zentrum f\u00fcr Speiser\u00f6hrenerkrankungen"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin","family":"Hemmerich","sequence":"additional","affiliation":[{"name":"Elisabeth-Krankenhaus Essen GmbH, Deutschland","place":["Essen"],"department":["Contilia Zentrum f\u00fcr Speiser\u00f6hrenerkrankungen"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefanie","family":"Albert","sequence":"additional","affiliation":[{"name":"Elisabeth-Krankenhaus Essen GmbH, Deutschland","place":["Essen"],"department":["Klinik f\u00fcr Allgemein-, Viszeral- und Unfallchirurgie"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Javed","family":"Parvez","sequence":"additional","affiliation":[{"name":"Elisabeth-Krankenhaus Essen GmbH, Deutschland","place":["Essen"],"department":["Klinik f\u00fcr Allgemein-, Viszeral- und Unfallchirurgie"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christin","family":"Lenk","sequence":"additional","affiliation":[{"name":"Elisabeth-Krankenhaus Essen GmbH, Deutschland","place":["Essen"],"department":["Klinik f\u00fcr An\u00e4sthesiologie, Operative Intensivmedizin und Schmerztherapie"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephan","family":"Johannsen","sequence":"additional","affiliation":[{"name":"Elisabeth-Krankenhaus Essen GmbH, Deutschland","place":["Essen"],"department":["Klinik f\u00fcr An\u00e4sthesiologie, Operative Intensivmedizin und Schmerztherapie"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter M.","family":"Markus","sequence":"additional","affiliation":[{"name":"Elisabeth-Krankenhaus Essen GmbH, Deutschland","place":["Essen"],"department":["Klinik f\u00fcr Allgemein-, Viszeral- und Unfallchirurgie"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2026,10,9]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"291","DOI":"10.1097\/SLA.0000000000002611","article-title":"Benchmarking complications associated with esophagectomy","volume":"269","author":"DE Low","year":"2019","journal-title":"Ann Surg"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"399","DOI":"10.1002\/ueg2.12523","article-title":"Updated German guideline on diagnosis and treatment of squamous cell carcinoma and adenocarcinoma of the esophagus","volume":"12","author":"R Porschen","year":"2024","journal-title":"United European Gastroenterol J"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"1073","DOI":"10.1016\/j.surg.2015.08.019","article-title":"Early outcome of thoracoscopic and hybrid esophagectomy: Propensity-matched comparative analysis","volume":"159","author":"L Bonavina","year":"2016","journal-title":"Surgery"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"128","DOI":"10.1055\/b-004-132230","volume-title":"\u00d6sophaguskarzinom \u2013 chirurgische Technik","author":"AH H\u00f6lscher","year":"2021"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"95","DOI":"10.1097\/SLA.0b013e3182590603","article-title":"Outcomes after minimally invasive esophagectomy: review of over 1000 patients","volume":"256","author":"JD Luketich","year":"2012","journal-title":"Ann Surg"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"232","DOI":"10.1097\/SLA.0000000000002171","article-title":"Minimally Invasive Versus Open Esophageal Resection: Three-year Follow-up of the Previously Reported Randomized Controlled Trial: the TIME Trial","volume":"266","author":"J Straatman","year":"2017","journal-title":"Ann Surg"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1016\/j.athoracsur.2018.08.039","article-title":"Does the Approach Matter? 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