{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T23:42:22Z","timestamp":1792194142673,"version":"4.4.0"},"reference-count":0,"publisher":"Georg Thieme Verlag KG","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Endoscopy"],"abstract":"<jats:p>Background and aims:\nEndoscopic ultrasound (EUS)-guided drainage is increasingly used for the management of postoperative pancreatic fluid collections (POPFC). We aimed to identify factors associated with clinical success, and to perform exploratory analyses of outcomes stratified by surgery type and stent type.\nPatients and methods:\nWe performed a retrospective multicenter cohort study including patients who underwent EUS-guided drainage of POPFC following pancreatic surgery between 2014 and August 2024 at three academic centers. The primary outcome was clinical success, defined as combined radiological and clinical resolution without the need for percutaneous or surgical step-up intervention.\nResults:\nA total of 265 patients were included (mean age 64\u00b114 years; 57% male; 52% underwent drainage \u226414 days after surgery, necrotic component in 51%). Clinical success was achieved in 194 patients (73%;  95% CI 67.5\u201378.1%), including 160 (60%;  95% CI 54.5\u201366.3%) after a single procedure and 34 after additional endoscopic reinterventions, while 20 patients (7.6%; 95% CI 4.4\u201310.7%)  required percutaneous or surgical step-up. Distal pancreatectomy, compared with pancreaticoduodenectomy, was associated with a higher rate of reintervention (32% vs. 20%, p=0.02) and independently associated with lower odds of clinical success (odds ratio 0.53, 95% confidence interval 0.29\u20130.98; p=0.04). \nConclusions:\nEUS-guided drainage for POPFC appears effective, with an acceptable safety profile in expert centers, achieving clinical resolution in the majority of patients. Distal pancreatectomy was associated with a more complex treatment course. These findings support the use of EUS-guided drainage as a central component in the management of POPFC.<\/jats:p>","DOI":"10.1055\/a-2975-4821","type":"journal-article","created":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T23:19:02Z","timestamp":1792192742000},"source":"Crossref","is-referenced-by-count":0,"title":["Predictors of clinical success in endoscopic ultrasound-guided drainage of postoperative pancreatic fluid collections"],"prefix":"10.1055","author":[{"given":"Hanne","family":"Hellinckx","sequence":"additional","affiliation":[{"name":"KU Leuven University Hospitals Leuven Gasthuisberg Campus, Flanders, Belgium","place":["Leuven"],"department":["Department of Gastroenterology and Hepatology"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2039-5022","authenticated-orcid":false,"given":"Michiel","family":"Bronswijk","sequence":"additional","affiliation":[{"name":"KU Leuven University Hospitals Leuven Gasthuisberg Campus, Flanders, Belgium","place":["Leuven"],"department":["Gastroenterology and Hepatology"]},{"name":"Imelda Hospital, Belgium","place":["Bonheiden"],"department":["Department of Gastroenterology and Hepatology"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4453-4624","authenticated-orcid":false,"given":"Gitte Aabye","family":"Olsen","sequence":"additional","affiliation":[{"name":"Copenhagen University Hospital Hvidovre, Capital Region of Denmark, Denmark","place":["Hvidovre"],"department":["Pancreatitis Centre East, Gastro Unit"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7280-1761","authenticated-orcid":false,"given":"Giuseppe","family":"Vanella","sequence":"additional","affiliation":[{"name":"Vita-Salute San Raffaele University, Lombardy, Italy","place":["Milan"],"department":["Department of Gastroenterology and Hepatology"]},{"name":"IRCCS San Raffaele Scientific Institute, Lombardy, Italy","place":["Milan"],"department":["Pancreatobiliary Endoscopy and Endosonography Division"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hanna","family":"Peeters","sequence":"additional","affiliation":[{"name":"KU Leuven University Hospitals Leuven Gasthuisberg Campus, Flanders, Belgium","place":["Leuven"],"department":["Department of Gastroenterology and Hepatology"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marie-Anne","family":"Noreillie","sequence":"additional","affiliation":[{"name":"KU Leuven University Hospitals Leuven Gasthuisberg Campus, Flanders, Belgium","place":["Leuven"],"department":["Department of Gastroenterology and Hepatology"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesco","family":"Frigo","sequence":"additional","affiliation":[{"name":"Copenhagen University Hospital Hvidovre, Capital Region of Denmark, Denmark","place":["Hvidovre"],"department":["Pancreatitis Centre East, Gastro Unit"]},{"name":"Vita-Salute San Raffaele University, Lombardy, Italy","place":["Milan"],"department":["Vita-Salute San Raffaele University"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-7438-3221","authenticated-orcid":false,"given":"Roberto","family":"Leone","sequence":"additional","affiliation":[{"name":"Vita-Salute San Raffaele University, Lombardy, Italy","place":["Milan"],"department":["Vita-Salute San Raffaele University"]},{"name":"IRCCS San Raffaele Scientific Institute, Lombardy, Italy","place":["Milan"],"department":["Pancreatobiliary Endoscopy and Endosonography Division"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0673-0939","authenticated-orcid":false,"given":"Hannah","family":"van Malenstein","sequence":"additional","affiliation":[{"name":"KU Leuven University Hospitals Leuven Gasthuisberg Campus, Flanders, Belgium","place":["Leuven"],"department":["Department of Gastroenterology and Hepatology"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0842-7813","authenticated-orcid":false,"given":"Wim","family":"Laleman","sequence":"additional","affiliation":[{"name":"KU Leuven University Hospitals Leuven Gasthuisberg Campus, Flanders, Belgium","place":["Leuven"],"department":["Department of Gastroenterology and Hepatology"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9969-019X","authenticated-orcid":false,"given":"Rogier","family":"Voermans","sequence":"additional","affiliation":[{"name":"Amsterdam UMC Locatie AMC, Noord-Holland, Netherlands","place":["Amsterdam"],"department":["Department of Gastroenterology and Hepatology"]},{"name":"Amsterdam Gastroenterology Endocrinology Metabolism, Netherlands","place":["Amsterdam"],"department":["Amsterdam Gastroenterology Endocrinology Metabolism"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6692-7720","authenticated-orcid":false,"given":"Paolo Giorgio","family":"Arcidiacono","sequence":"additional","affiliation":[{"name":"Vita-Salute San Raffaele University, Lombardy, Italy","place":["Milan"],"department":["Vita-Salute San Raffaele University"]},{"name":"IRCCS San Raffaele Scientific Institute, Lombardy, Italy","place":["Milan"],"department":["Pancreatobiliary Endoscopy and Endosonography Division"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Halit","family":"Topal","sequence":"additional","affiliation":[{"name":"KU Leuven University Hospitals Leuven Gasthuisberg Campus, Flanders, Belgium","place":["Leuven"],"department":["Department of Visceral Surgery"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Baki","family":"Topal","sequence":"additional","affiliation":[{"name":"KU Leuven University Hospitals Leuven Gasthuisberg Campus, Flanders, Belgium","place":["Leuven"],"department":["Department of Visceral Surgery"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0477-4532","authenticated-orcid":false,"given":"Roy L.J.","family":"van Wanrooij","sequence":"additional","affiliation":[{"name":"Amsterdam UMC Locatie VUmc, Netherlands","place":["Amsterdam"],"department":["Department of Gastroenterology and Hepatology"]},{"name":"Amsterdam Gastroenterology Endocrinology Metabolism, Netherlands","place":["Amsterdam"],"department":["Department of Gastroenterology and Hepatology"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Schalk","family":"Van der Merwe","sequence":"additional","affiliation":[{"name":"KU Leuven University Hospitals Leuven Gasthuisberg Campus, Flanders, Belgium","place":["Leuven"],"department":["Department of Gastroenterology and 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