{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T23:46:23Z","timestamp":1792107983555,"version":"4.4.0"},"reference-count":0,"publisher":"Georg Thieme Verlag KG","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Ultraschall Med"],"abstract":"<jats:p>Purpose\nChoroid plexus cysts (CPC) are frequently detected prenatally and are generally considered benign. However, data on their postnatal course, growth dynamics, and clinical relevance are limited.\nThis study investigates the long-term development, growth patterns, and resolution of CPC in newborns and infants.\nMaterials and Methods\nWe retrospectively analysed 251 CPC in 164 patients admitted to a neonatal intensive care unit between 2014 and 2024. CPC were assessed using serial cranial ultrasonography. Growth dynamics were evaluated using Kaplan\u2013Meier survival analysis and chi-square testing.\nResults\nCPC were identified in both preterm and term infants, with a mean CPC size of 4.1\u202fmm at diagnosis. Of 177 CPC with serial imaging data, 40% were not present on initial scans and appeared postnatally. The median time to resolution was 108 days. Many CPC initially increased in size before decreasing or resolving completely. A chi-square analysis showed a significant shift in growth behaviour between the 6- and 12-week follow-up groups (p\u202f=\u202f0.006). No infant required intervention related to CPC.\nConclusion\nPostnatal CPC often follow a benign, self-limiting course, meaning they tend to resolve naturally over time, with dynamic growth patterns. Routine monitoring of isolated CPC in asymptomatic infants may not be needed in all cases.\n\nZiel\nChoroidplexuszysten (CPC) werden h\u00e4ufig pr\u00e4natal festgestellt und gelten im Allgemeinen als gutartig. Allerdings liegen nur begrenzte Daten zu ihrem postnatalen Verlauf, ihrer Wachstumsdynamik und ihrer klinischen Relevanz vor.\nDiese Studie untersucht die langfristige Entwicklung, die Wachstumsmuster und die R\u00fcckbildung von CPC bei Neugeborenen und S\u00e4uglingen.\nMaterialien und Methoden\nWir analysierten retrospektiv 251 CPC bei 164 Patienten, die zwischen 2014 und 2024 auf eine neonatologische Intensivstation aufgenommen wurden. Die CPC wurden mittels serieller kranialer Sonographie beurteilt. Die Wachstumsdynamik wurde mittels Kaplan-Meier-\u00dcberlebensanalyse und Chi-Quadrat-Test ausgewertet.\nErgebnisse\nCPC wurden sowohl bei Fr\u00fchgeborenen als auch bei termingeborenen S\u00e4uglingen festgestellt, wobei die durchschnittliche CPC-Gr\u00f6\u00dfe bei der Diagnose 4,1 mm betrug. Von 177 CPC mit seriellen Bildgebungsdaten waren 40 % bei den ersten Untersuchungen nicht nachweisbar und traten postnatal auf. Die mediane Zeit bis zur R\u00fcckbildung betrug 108 Tage. Viele CPC nahmen zun\u00e4chst an Gr\u00f6\u00dfe zu, bevor sie sich verkleinerten oder vollst\u00e4ndig zur\u00fcckbildeten. Eine Chi-Quadrat-Analyse zeigte eine signifikante Verschiebung im Wachstumsverhalten zwischen den 6- und 12-Wochen-Nachbeobachtungsgruppen (p = 0,006). Bei keinem S\u00e4ugling war eine interventionelle Behandlung im Zusammenhang mit dem CPC erforderlich.\nSchlussfolgerung\nPostnatale CPC zeigen in der Regel einen gutartigen und selbstlimitierenden Verlauf mit dynamischen Wachstumsmustern und spontaner R\u00fcckbildung. Eine routinem\u00e4\u00dfige Verlaufskontrolle isolierter CPC bei asymptomatischen S\u00e4uglingen ist m\u00f6glicherweise nicht in allen F\u00e4llen erforderlich.<\/jats:p>","DOI":"10.1055\/a-2982-3894","type":"journal-article","created":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T22:58:00Z","timestamp":1792105080000},"source":"Crossref","is-referenced-by-count":0,"title":["Postnatal Dynamics of Choroid Plexus Cysts in Newborns and Infants: A Retrospective Single-Center Cohort Study"],"prefix":"10.1055","author":[{"given":"Aliena","family":"Juhl","sequence":"additional","affiliation":[{"name":"Friedrich-Alexander University Erlangen-Nuremberg, Bavaria, Germany","place":["Erlangen"],"department":["Department of Pediatrics and Adolescent Medicine"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J\u00f6rg","family":"J\u00fcngert","sequence":"additional","affiliation":[{"name":"Friedrich-Alexander University Erlangen-Nuremberg, Bavaria, Germany","place":["Erlangen"],"department":["Department of Pediatrics and Adolescent Medicine"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steven","family":"Hebert","sequence":"additional","affiliation":[{"name":"Friedrich-Alexander University Erlangen-Nuremberg, Bavaria, Germany","place":["Erlangen"],"department":["Department of Pediatrics and Adolescent Medicine"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gregor","family":"Siebenlist","sequence":"additional","affiliation":[{"name":"Friedrich-Alexander University Erlangen-Nuremberg, Bavaria, Germany","place":["Erlangen"],"department":["Department of Pediatrics and Adolescent Medicine"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Linda-Marie","family":"Mulzer","sequence":"additional","affiliation":[{"name":"Friedrich-Alexander University Erlangen-Nuremberg, Bavaria, Germany","place":["Erlangen"],"department":["Department of Pediatrics and Adolescent Medicine"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrick","family":"Morhart","sequence":"additional","affiliation":[{"name":"Klinikum Bayreuth GmbH, Bavaria, Germany","place":["Bayreuth"],"department":["Department of Pediatrics and Adolescent Medicine"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joachim","family":"Woelfle","sequence":"additional","affiliation":[{"name":"Friedrich-Alexander University Erlangen-Nuremberg, Bavaria, Germany","place":["Erlangen"],"department":["Department of Pediatrics and Adolescent Medicine"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3535-2626","authenticated-orcid":false,"given":"Ferdinand","family":"Knieling","sequence":"additional","affiliation":[{"name":"Friedrich-Alexander University Erlangen-Nuremberg, Bavaria, Germany","place":["Erlangen"],"department":["Department of Pediatrics and Adolescent Medicine"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heiko","family":"Reutter","sequence":"additional","affiliation":[{"name":"Friedrich-Alexander University Erlangen-Nuremberg, Bavaria, Germany","place":["Erlangen"],"department":["Department of Pediatrics and Adolescent Medicine"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7620-3344","authenticated-orcid":false,"given":"Gregor","family":"Hanslik","sequence":"additional","affiliation":[{"name":"Friedrich-Alexander University Erlangen-Nuremberg, Bavaria, Germany","place":["Erlangen"],"department":["Department of Pediatrics and Adolescent Medicine"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","container-title":["Ultraschall in der Medizin - European Journal of Ultrasound"],"original-title":[],"language":"de","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/a-2982-3894.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T22:58:00Z","timestamp":1792105080000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/a-2982-3894"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,10,15]]},"references-count":0,"URL":"https:\/\/doi.org\/10.1055\/a-2982-3894","archive":["Portico","CLOCKSS"],"relation":{},"ISSN":["0172-4614","1438-8782"],"issn-type":[{"value":"0172-4614","type":"print"},{"value":"1438-8782","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2026,10,15]]},"published":{"date-parts":[[2026,10,15]]}}}