{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T00:34:06Z","timestamp":1793061246764,"version":"4.5.0"},"reference-count":14,"publisher":"Georg Thieme Verlag KG","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Thorac Cardiovasc Surg"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Coronary artery disease (CAD) in young adults is uncommon but associated with substantial long-term morbidity. Limited evidence exists regarding the long-term outcomes of bilateral internal thoracic artery (BITA) grafting in this population. This study evaluates perioperative and long-term outcomes of BITA revascularization in young adults undergoing coronary artery bypass grafting (CABG) and compares survival outcomes with those of the general population.<\/jats:p>\n                  <jats:p>A retrospective single-center observational study was conducted in 67 young patients (39\u2009\u00b1\u20093 years) who underwent BITA grafting for multivessel CAD. Perioperative outcomes, long-term overall survival, major adverse cardio-cerebral events (MACEs), and repeat revascularization were assessed. Long-term outcomes were evaluated using Kaplan\u2013Meier analysis. Further survival analysis was conducted using an age- and sex-adjusted general population matched for age, sex, and calendar year.<\/jats:p>\n                  <jats:p>BITA grafting was associated with very low perioperative morbidity. The median follow-up was 17 years, with an estimated overall survival at 20 years of 74% (0.74, 95% confidence interval [CI]: 0.52\u20130.87) and freedom from MACEs at 20 years of 70% (0.70, 95% CI: 0.49\u20130.84). Sternal wound complications were infrequent (1.5%).<\/jats:p>\n                  <jats:p>BITA revascularization in young adults demonstrates excellent long-term survival, with survival comparable to that of the age- and sex-matched general population during the first 15 years after surgery, along with durable event-free outcomes, supporting its use as a durable revascularization strategy in this population.<\/jats:p>","DOI":"10.1055\/a-2983-8877","type":"journal-article","created":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T23:20:26Z","timestamp":1792452026000},"source":"Crossref","is-referenced-by-count":0,"title":["Long-term Performance of Bilateral Internal Thoracic Artery Grafts in Young Adults"],"prefix":"10.1055","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8312-330X","authenticated-orcid":false,"given":"Dritan","family":"Useini","sequence":"additional","affiliation":[{"name":"University Hospital Basel, BS, Switzerland","place":["Basel"],"department":["Department of Cardiac Surgery"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brigitta","family":"Gahl","sequence":"additional","affiliation":[{"name":"University Hospital Basel, BS, Switzerland","place":["Basel"],"department":["Department of Cardiac Surgery"]},{"name":"Surgical Outcome Research Center Basel, University Hospital Basel, BS, Switzerland","place":["Basel"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcus","family":"Franz","sequence":"additional","affiliation":[{"name":"Cardiovascular Center Hersfeld-Rotenburg, HE, Germany","place":["Rotenburg an der Fulda"],"department":["Department of Cardiology, Angiology and Intensive Care Medicine"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ralf","family":"Degenhardt","sequence":"additional","affiliation":[{"name":"Institute for Clinical Research, Cardiovascular Center Hersfeld-Rotenburg, HE, Germany","place":["Rotenburg an der Fulda"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zulfugar Timur","family":"Taghiyev","sequence":"additional","affiliation":[{"name":"Kerckhoff-Clinic, Campus Kerckhoff, Justus-Liebig-University of Giessen, Germany","place":["Bad Nauheim"],"department":["Department of Cardiac Surgery"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ingo","family":"Kutschka","sequence":"additional","affiliation":[{"name":"University Hospital Basel, BS, Switzerland","place":["Basel"],"department":["Department of Cardiac Surgery"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hassina","family":"Baraki","sequence":"additional","affiliation":[{"name":"University Hospital Basel, BS, Switzerland","place":["Basel"],"department":["Department of Cardiac Surgery"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2026,10,26]]},"reference":[{"issue":"15","key":"ref1","doi-asserted-by":"crossref","first-page":"1868","DOI":"10.1016\/j.jacc.2019.08.1002","article-title":"Long-term evolution of premature coronary artery disease","volume":"74","author":"J P Collet","year":"2019","journal-title":"J Am Coll Cardiol"},{"issue":"02","key":"ref2","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/j.jacc.2021.09.005","article-title":"2021 ACC\/AHA\/SCAI guideline for coronary artery revascularization: executive summary: a report of the American College of Cardiology\/American Heart Association Joint Committee on Clinical Practice Guidelines","volume":"79","author":"J S Lawton","year":"2022","journal-title":"J Am Coll Cardiol"},{"issue":"02","key":"ref3","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1093\/eurheartj\/ehy394","article-title":"2018 ESC\/EACTS guidelines on 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