{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T19:46:03Z","timestamp":1760298363819,"version":"3.40.1"},"reference-count":17,"publisher":"MDPI AG","issue":"2","license":[{"start":{"date-parts":[[2011,6,1]],"date-time":"2011-06-01T00:00:00Z","timestamp":1306886400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Craniomaxillofacial Trauma &amp; Reconstruction"],"published-print":{"date-parts":[[2011,6]]},"abstract":"<jats:p> We report the first case of syngnathia with hypophyseal duplication and describe the central nervous system (CNS) and craniofacial anomalies associated with hypophyseal duplication in the reported autopsy case. We studied clinical reports, scanner images, and autopsy results of a 2-months-old female baby. The propositus had frontonasal dysmorphism, retrognathia, and bifid tongue. She also presented maxillomandibular bony fusion (syngnathia) and an intraoral hairy polyp. In the cranium, the sella turcica was broadened, with two complete hypophyses and two infundibulums. The CNS had both olfactory bulbs and corpus callosum agenesis. There are 27 previous cases of maxillomandibular fusion and seven previous autopsy cases of hypophyseal duplication associated with other frontonasal malformations. As far as the authors know, this is the first case reported in the literature that associates syngnathia with duplication of the craniofacial midline including hypophyseal duplication. <\/jats:p>","DOI":"10.1055\/s-0031-1279674","type":"journal-article","created":{"date-parts":[[2011,5,16]],"date-time":"2011-05-16T05:01:02Z","timestamp":1305522062000},"page":"113-120","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":10,"title":["Atypical Case of Congenital Maxillomandibular Fusion with Duplication of the Craniofacial Midline"],"prefix":"10.3390","volume":"4","author":[{"given":"Lorena Pingarr\u00f3n","family":"Mart\u00edn","sequence":"first","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery, La Paz University Hospital, Madrid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mercedes Mart\u00edn","family":"P\u00e9rez","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery, La Paz University Hospital, Madrid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elena G\u00f3mez","family":"Garc\u00eda","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery, La Paz University Hospital, Madrid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Javier Gonz\u00e1lez","family":"Mart\u00edn-Moro","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery, La Paz University Hospital, Madrid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jose Ignacio Rodr\u00edguez","family":"Gonz\u00e1lez","sequence":"additional","affiliation":[{"name":"Department of Pathology, La Paz University Hospital, Madrid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Miguel Burgue\u00f1o","family":"Garc\u00eda","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery, La Paz University Hospital, Madrid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2011,6,1]]},"reference":[{"key":"bibr1-s-0031-1279674","doi-asserted-by":"publisher","DOI":"10.1016\/j.tripleo.2005.10.051"},{"key":"bibr2-s-0031-1279674","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1936.02770200025009"},{"key":"bibr3-s-0031-1279674","doi-asserted-by":"publisher","DOI":"10.1054\/ijom.2000.0009"},{"key":"bibr4-s-0031-1279674","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcms.2004.01.005"},{"key":"bibr5-s-0031-1279674","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcms.2009.01.001"},{"key":"bibr6-s-0031-1279674","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcms.2006.10.005"},{"key":"bibr7-s-0031-1279674","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.17.10.961"},{"key":"bibr8-s-0031-1279674","doi-asserted-by":"publisher","DOI":"10.1097\/00006534-198309000-00023"},{"key":"bibr9-s-0031-1279674","doi-asserted-by":"publisher","DOI":"10.1016\/0030-4220(65)90268-9"},{"key":"bibr10-s-0031-1279674","doi-asserted-by":"publisher","DOI":"10.1597\/1545-1569(2000)037<0083:ETROTC>2.3.CO;2"},{"key":"bibr11-s-0031-1279674","doi-asserted-by":"publisher","DOI":"10.1007\/BF00691602"},{"key":"bibr12-s-0031-1279674","doi-asserted-by":"publisher","DOI":"10.1186\/1749-8104-4-43"},{"key":"bibr13-s-0031-1279674","doi-asserted-by":"publisher","DOI":"10.1597\/1545-1569_1997_034_0141_cbsapc_2.3.co_2"},{"key":"bibr14-s-0031-1279674","doi-asserted-by":"publisher","DOI":"10.1097\/00006534-197901000-00029"},{"issue":"2","key":"bibr15-s-0031-1279674","first-page":"5","volume":"1","author":"Dobrow B","year":"1983","journal-title":"J Clin Dysmorphol"},{"key":"bibr16-s-0031-1279674","doi-asserted-by":"publisher","DOI":"10.1177\/019459988509300119"},{"key":"bibr17-s-0031-1279674","doi-asserted-by":"publisher","DOI":"10.1097\/00000542-197910000-00013"}],"container-title":["Craniomaxillofacial Trauma &amp; 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