{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T09:30:55Z","timestamp":1783416655956,"version":"3.54.6"},"reference-count":15,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2015,6,5]],"date-time":"2015-06-05T00:00:00Z","timestamp":1433462400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Global Spine Journal"],"published-print":{"date-parts":[[2016,2]]},"abstract":"<jats:sec>\n                    <jats:title>Study Design<\/jats:title>\n                    <jats:p>Retrospective study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>Hyperlipidemia (HL) and hypertension (HT) lead to systemic atherosclerosis. Not only atherosclerosis but also bone fragility and\/or low bone mineral density result from diabetes mellitus (DM) and chronic kidney disease (CKD). The purpose of this study was to examine whether these lifestyle-related diseases affected surgical outcomes after posterior lumbar interbody fusion (PLIF).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>The subjects comprised 122 consecutive patients who underwent single-level PLIF for degenerative lumbar spinal disorders. The clinical results were assessed using the Japanese Orthopaedic Association (JOA) score before surgery and at 2 years postoperatively. The fusion status was graded as union in situ, collapsed union, or nonunion at 2 years after surgery. The abdominal aorta calcification (AAC) score was assessed using preoperative lateral radiographs of the lumbar spine.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>HL did not significantly affect the JOA score recovery rate. On the other hand, HT and CKD (stage 3 to 4) had a significant adverse effect on the recovery rate. The recovery rate was also lower in the DM group than in the non-DM group, but the difference was not significant. The AAC score was negatively correlated with the JOA score recovery rate. The fusion status was not significantly affected by HL, HT, DM, or CKD; however, the AAC score was significantly higher in the collapsed union and nonunion group than in the union in situ group.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>At 2 years after PLIF, the presence of HT, CKD, and AAC was associated with significantly worse clinical outcomes, and advanced AAC significantly affected fusion status.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1055\/s-0035-1554774","type":"journal-article","created":{"date-parts":[[2015,6,5]],"date-time":"2015-06-05T18:34:35Z","timestamp":1433529275000},"page":"2-6","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":12,"title":["Lifestyle-Related Diseases Affect Surgical Outcomes after Posterior Lumbar Interbody Fusion"],"prefix":"10.1177","volume":"6","author":[{"given":"Hironobu","family":"Sakaura","sequence":"first","affiliation":[{"name":"Department of Orthopaedic Surgery, Kansai Rosai Hospital, Amagasaki, Hyogo, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toshitada","family":"Miwa","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Kansai Rosai Hospital, Amagasaki, Hyogo, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomoya","family":"Yamashita","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Osaka Rosai Hospital, Kitaku, Sakai, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yusuke","family":"Kuroda","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Kansai Rosai Hospital, Amagasaki, Hyogo, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tetsuo","family":"Ohwada","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Kansai Rosai Hospital, Amagasaki, Hyogo, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2015,6,5]]},"reference":[{"key":"bibr1-s-0035-1554774","doi-asserted-by":"publisher","DOI":"10.1507\/endocrj.EJ11-0063"},{"key":"bibr2-s-0035-1554774","doi-asserted-by":"publisher","DOI":"10.1007\/s11926-009-0025-1"},{"key":"bibr3-s-0035-1554774","doi-asserted-by":"publisher","DOI":"10.1097\/BRS.0b013e31828a2517"},{"key":"bibr4-s-0035-1554774","doi-asserted-by":"publisher","DOI":"10.2106\/00004623-199312000-00013"},{"key":"bibr5-s-0035-1554774","doi-asserted-by":"publisher","DOI":"10.1302\/0301-620X.76B2.8113279"},{"issue":"8","key":"bibr6-s-0035-1554774","first-page":"617","volume":"29","author":"Bendo J A","year":"2000","journal-title":"Am J Orthop"},{"key":"bibr7-s-0035-1554774","doi-asserted-by":"publisher","DOI":"10.1007\/s00586-003-0643-7"},{"key":"bibr8-s-0035-1554774","doi-asserted-by":"publisher","DOI":"10.1097\/00007632-199601150-00016"},{"key":"bibr9-s-0035-1554774","doi-asserted-by":"publisher","DOI":"10.1142\/S0218957798000184"},{"key":"bibr10-s-0035-1554774","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9150(97)00106-8"},{"key":"bibr11-s-0035-1554774","doi-asserted-by":"publisher","DOI":"10.1291\/hypres.26.163"},{"key":"bibr12-s-0035-1554774","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejvs.2009.02.006"},{"key":"bibr13-s-0035-1554774","doi-asserted-by":"publisher","DOI":"10.1097\/BRS.0b013e31825e21b2"},{"key":"bibr14-s-0035-1554774","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2796.2006.01640.x"},{"key":"bibr15-s-0035-1554774","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2003-030964"}],"container-title":["Global Spine Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1055\/s-0035-1554774","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1055\/s-0035-1554774","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1055\/s-0035-1554774","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T07:14:54Z","timestamp":1777446894000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1055\/s-0035-1554774"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,6,5]]},"references-count":15,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2016,2]]}},"alternative-id":["10.1055\/s-0035-1554774"],"URL":"https:\/\/doi.org\/10.1055\/s-0035-1554774","relation":{},"ISSN":["2192-5682","2192-5690"],"issn-type":[{"value":"2192-5682","type":"print"},{"value":"2192-5690","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,6,5]]}}}