{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,14]],"date-time":"2026-02-14T08:46:07Z","timestamp":1771058767949,"version":"3.50.1"},"reference-count":0,"publisher":"Georg Thieme Verlag KG","issue":"04","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Thorac cardiovasc Surg"],"published-print":{"date-parts":[[2018,6]]},"abstract":"<jats:p>\n            Background\u2003To examine the results of myectomy and mitral valve surgery for systolic anterior motion (SAM) of the mitral valve and left ventricular outflow tract obstruction (LVOTO) with a relatively thin interventricular septum.<\/jats:p><jats:p>\n            Methods\u2003The subjects were 12 patients with SAM and LVOTO. Eight had hypertrophic obstructive cardiomyopathy (HOCM) with a mean interventricular septal thickness of 16 mm. Three had sigmoid septum and one had an unknown etiology. For HOCM, isolated extended myectomy was performed when mitral regurgitation was mild (n\u2009=\u20091) and extended myectomy plus mitral valve surgery was performed when mitral regurgitation was more than mild (n\u2009=\u20094) or primary valve etiologies existed (n\u2009=\u20093). Myectomy was performed for the three cases with sigmoid septum. Myectomy plus height reduction of the posterior mitral leaflet was performed for the one case with the unknown etiology of SAM.<\/jats:p><jats:p>\n            Results\u2003In the patients with HOCM, the maximum LVOT pressure gradient significantly decreased from 140\u2009\u00b1\u200918 to 16\u2009\u00b1\u20096 and 3\u2009\u00b1\u20093\u2009mm Hg, while mitral regurgitation significantly decreased from 2.3\u2009\u00b1\u20090.5 to 0.5\u2009\u00b1\u20090.3 and 0.4\u2009\u00b1\u20090.2 at pre-op, early post-op, and last follow-up (3\u2009\u00b1\u20091 years), respectively. In the other etiologies, the maximum LVOT pressure gradient changed from 56\u2009\u00b1\u200915 to 25\u2009\u00b1\u200915 and 5\u2009\u00b1\u20094\u2009mm Hg; mitral regurgitation changed from 2.0\u2009\u00b1\u20090.6 to 1.3\u2009\u00b1\u20090.3 and 1.3\u2009\u00b1\u20090.8, at pre-op, early post-op, and the last follow-up (3\u2009\u00b1\u20092 years), respectively.<\/jats:p><jats:p>\n            Conclusion\u2003Myectomy with mitral valve surgery is an option for SAM and LVOTO in patients with a relatively thin interventricular septum.<\/jats:p>","DOI":"10.1055\/s-0035-1570748","type":"journal-article","created":{"date-parts":[[2016,1,13]],"date-time":"2016-01-13T03:19:18Z","timestamp":1452655158000},"page":"307-312","source":"Crossref","is-referenced-by-count":8,"title":["Surgery for Left Ventricular Outflow Tract Obstruction with a Relatively Thin Interventricular Septum"],"prefix":"10.1055","volume":"66","author":[{"given":"Hiroshi","family":"Sugiki","sequence":"first","affiliation":[{"name":"Department of Cardiovascular Surgery, Hokko Memorial Hospital, Sapporo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tomonori","family":"Ooka","sequence":"first","affiliation":[{"name":"Department of Cardiovascular and Thoracic Surgery, Hokkaido University Graduate School of Medicine, Sapporo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroki","family":"Kato","sequence":"first","affiliation":[{"name":"Emergency and Critical Care Center, Hokkaido University Hospital, Sapporo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Satoru","family":"Wakasa","sequence":"first","affiliation":[{"name":"Department of Cardiovascular and Thoracic Surgery, Hokkaido University Graduate School of Medicine, Sapporo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tsuyoshi","family":"Tachibana","sequence":"first","affiliation":[{"name":"Department of Cardiovascular and Thoracic Surgery, Hokkaido University Graduate School of Medicine, Sapporo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshiro","family":"Matsui","sequence":"first","affiliation":[{"name":"Department of Cardiovascular and Thoracic Surgery, Hokkaido University Graduate School of Medicine, Sapporo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yasushige","family":"Shingu","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular and Thoracic Surgery, Hokkaido University Hospital, Sapporo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2016,1,12]]},"container-title":["The Thoracic and Cardiovascular Surgeon"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/s-0035-1570748.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,6,3]],"date-time":"2018-06-03T22:31:21Z","timestamp":1528065081000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/s-0035-1570748"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,1,12]]},"references-count":0,"journal-issue":{"issue":"04","published-online":{"date-parts":[[2018,6,3]]},"published-print":{"date-parts":[[2018,6]]}},"URL":"https:\/\/doi.org\/10.1055\/s-0035-1570748","relation":{},"ISSN":["0171-6425","1439-1902"],"issn-type":[{"value":"0171-6425","type":"print"},{"value":"1439-1902","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,1,12]]}}}