{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,4]],"date-time":"2026-04-04T02:39:07Z","timestamp":1775270347661,"version":"3.50.1"},"reference-count":0,"publisher":"Georg Thieme Verlag KG","issue":"02","license":[{"start":{"date-parts":[[2017,4,7]],"date-time":"2017-04-07T00:00:00Z","timestamp":1491523200000},"content-version":"vor","delay-in-days":6,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Facial plast Surg"],"published-print":{"date-parts":[[2017,4]]},"abstract":"<jats:p>\n            Objective\u2003To evaluate the safety and effectiveness of an absorbable implant for lateral cartilage support in subjects with nasal valve collapse (NVC) with 12 months follow-up.<\/jats:p><jats:p>\n            Methods\u2003Thirty subjects with Nasal Obstruction Symptom Evaluation (NOSE) score\u2009\u2265\u200955 and isolated NVC were treated; 14 cases were performed in an operating suite under general anesthesia and 16 cases were performed in a clinic-based setting under local anesthesia. The implant, a polylactic acid copolymer, was placed with a delivery tool within the nasal wall to provide lateral cartilage support. Subjects were followed up through 12 months postprocedure.<\/jats:p><jats:p>\n            Results\u2003Fifty-six implants were placed in 30 subjects. The mean preoperative NOSE score was 76.7\u2009\u00b1\u200914.8, with a range of 55 to 100. At 12 months, the mean score was 35.2\u2009\u00b1\u200929.2, reflecting an average within-patient reduction of \u201340.9\u2009\u00b1\u200931.2 points. The majority (76%) of the subjects were responders defined as having at least one NOSE class improvement or a NOSE score reduction of at least 20%. There were no adverse changes in cosmetic appearance at 12 months postprocedure. Three implants in three subjects required retrieval within 30 days postprocedure and resulted in no clinical sequelae.<\/jats:p><jats:p>\n            Conclusion\u2003This study demonstrates safety and effectiveness of an absorbable implant for lateral cartilage support in subjects with NVC at 12 months postprocedure.<\/jats:p>","DOI":"10.1055\/s-0037-1598655","type":"journal-article","created":{"date-parts":[[2017,4,7]],"date-time":"2017-04-07T18:37:23Z","timestamp":1491590243000},"page":"233-240","source":"Crossref","is-referenced-by-count":33,"title":["Absorbable Implant to Treat Nasal Valve Collapse"],"prefix":"10.1055","volume":"33","author":[{"given":"Marion","family":"Nicol\u00f3","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, Head and Neck Surgery, Ludwig Maximilian University of Munich, Munich, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Klaus","family":"Stelter","sequence":"additional","affiliation":[{"name":"HNO Zentrum Mangfall-Inn, Rosenheim, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Haneen","family":"Sadick","sequence":"additional","affiliation":[{"name":"Division of Facial Plastic Surgery, Department of Otorhinolaryngology, University of Mannheim, Mannheim, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Murat","family":"Bas","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, Head and Neck Surgery, Klinikum rechts der Isar, Technical University Munich, Munich, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexander","family":"Berghaus","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, Head and Neck Surgery, Ludwig Maximilian University of Munich, Munich, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2017,4,7]]},"container-title":["Facial Plastic Surgery"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/s-0037-1598655.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,6]],"date-time":"2019-05-06T14:43:04Z","timestamp":1557153784000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/s-0037-1598655"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,4]]},"references-count":0,"journal-issue":{"issue":"02","published-online":{"date-parts":[[2017,4,7]]},"published-print":{"date-parts":[[2017,4]]}},"URL":"https:\/\/doi.org\/10.1055\/s-0037-1598655","relation":{},"ISSN":["0736-6825","1098-8793"],"issn-type":[{"value":"0736-6825","type":"print"},{"value":"1098-8793","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,4]]}}}