{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,10]],"date-time":"2026-04-10T10:30:23Z","timestamp":1775817023191,"version":"3.50.1"},"reference-count":0,"publisher":"Georg Thieme Verlag KG","issue":"12","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Amer J Perinatol"],"published-print":{"date-parts":[[2017,10]]},"abstract":"<jats:p>\n            Objective\u2003This study aims to determine the effects of paracetamol versus ibuprofen treatment given to preterm infants for the pharmacological closure of patent ductus arteriosus (PDA) on neurodevelopmental outcomes at 18 to 24 months' corrected age.<\/jats:p><jats:p>\n            Method\u2003A follow-up study was conducted to evaluate the neurodevelopmental outcomes of preterm infants (gestational age\u2009\u2264\u200930 weeks) enrolled in a randomized controlled trial comparing oral paracetamol versus oral ibuprofen for the closure of PDA. The developmental assessment was done by using \u201cBayley Scales of Infant Development, Second Edition\u201d at 18 to 24 months' corrected age.<\/jats:p><jats:p>\n            Results\u2003A total of 80 infants completed the trial protocol. Of the 75 infants eligible for follow-up, 61 infants (30 in the paracetamol group and 31 in the ibuprofen group) were evaluated. There was no significant difference in neurodevelopmental outcomes between the two groups.<\/jats:p><jats:p>\n            Conclusion\u2003The neurodevelopmental outcomes did not differ among the preterm infants who receive either paracetamol or ibuprofen at 18 to 24 months' corrected age.<\/jats:p>","DOI":"10.1055\/s-0037-1601564","type":"journal-article","created":{"date-parts":[[2017,4,10]],"date-time":"2017-04-10T23:01:23Z","timestamp":1491865283000},"page":"1185-1189","source":"Crossref","is-referenced-by-count":40,"title":["Neurodevelopmental Outcomes of Preterm Infants Treated with Oral Paracetamol Versus Ibuprofen for Patent Ductus Arteriosus"],"prefix":"10.1055","volume":"34","author":[{"given":"Zeynep","family":"Eras","sequence":"first","affiliation":[{"name":"Developmental Behavioral Pediatrics Unit, Zekai Tahir Burak Maternity Teaching Hospital, Ankara, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nurdan","family":"Uras","sequence":"first","affiliation":[{"name":"Division of Neonatology, Zekai Tahir Burak Maternity Teaching Hospital, Ankara, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fuat","family":"Canpolat","sequence":"first","affiliation":[{"name":"Division of Neonatology, Zekai Tahir Burak Maternity Teaching Hospital, Ankara, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Omer","family":"Erdeve","sequence":"first","affiliation":[{"name":"Division of Neonatology, Department of Pediatrics, Ankara University School of Medicine, Ankara, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Serife","family":"Oguz","sequence":"first","affiliation":[{"name":"Division of Neonatology, Zekai Tahir Burak Maternity Teaching Hospital, Ankara, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mehmet","family":"Oncel","sequence":"additional","affiliation":[{"name":"Division of Neonatology, Department of Pediatrics, Katip \u00c7elebi University, \u0130zmir, Turkey"},{"name":"Division of Neonatology, Zekai Tahir Burak Maternity Teaching Hospital, Ankara, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2017,4,10]]},"container-title":["American Journal of Perinatology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/s-0037-1601564.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,12,19]],"date-time":"2017-12-19T12:40:56Z","timestamp":1513687256000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/s-0037-1601564"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,4,10]]},"references-count":0,"journal-issue":{"issue":"12","published-online":{"date-parts":[[2017,9,28]]},"published-print":{"date-parts":[[2017,10]]}},"URL":"https:\/\/doi.org\/10.1055\/s-0037-1601564","relation":{},"ISSN":["0735-1631","1098-8785"],"issn-type":[{"value":"0735-1631","type":"print"},{"value":"1098-8785","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,4,10]]}}}