{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,10]],"date-time":"2023-10-10T14:32:16Z","timestamp":1696948336860},"reference-count":0,"publisher":"Georg Thieme Verlag KG","issue":"12","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Amer J Perinatol"],"published-print":{"date-parts":[[2017,10]]},"abstract":"<jats:p>\n            Objective\u2003We compared the accuracy of serum intact parathyroid hormone (iPTH), alkaline phosphatase (ALP), and phosphate (phos) levels for diagnosing severe metabolic bone disease (MBD) in very low-birth-weight (VLBW) infants with severe bronchopulmonary dysplasia (BPD).<\/jats:p><jats:p>\n            Study Design\u2003Retrospective analysis of VLBW infants with severe BPD admitted between 2010 and 2012 and with\u2009\u2265\u20091 iPTH, ALP, and phos level collected within a similar 72-hour period. MBD severity was classified by serial radiography.<\/jats:p><jats:p>\n            Results\u2003Laboratory values were available for 65 infants, of whom 24 (36.9%) developed severe MBD. A maximum ALP &gt; 660 IU\/L was the most accurate for diagnosing severe MBD (area under the curve: 88.4%; 95% confidence interval [CI]: 77.2\u201394.5%). Maximum iPTH was the least accurate (optimal cut point\u2009&gt;\u2009130 pg\/mL; area under the curve: 70.5%; 95% CI: 58.2\u201381.4).<\/jats:p><jats:p>\n            Conclusion\u2003Maximum ALP was more accurate than iPTH or phos for diagnosing severe MBD among preterm infants with severe BPD.<\/jats:p>","DOI":"10.1055\/s-0037-1602419","type":"journal-article","created":{"date-parts":[[2017,4,21]],"date-time":"2017-04-21T18:54:08Z","timestamp":1492800848000},"page":"1199-1204","source":"Crossref","is-referenced-by-count":3,"title":["Comparison of Intact Parathyroid Hormone, Alkaline Phosphatase, Phosphate Levels for Diagnosing Severe Metabolic Bone Disease in Infants with Severe Bronchopulmonary Dysplasia"],"prefix":"10.1055","volume":"34","author":[{"given":"Erin","family":"Tkach","sequence":"first","affiliation":[{"name":"Division of Neonatology, Department of Pediatrics, University of Pennsylvania, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ammie","family":"White","sequence":"first","affiliation":[{"name":"Division of Radiology, Department of Pediatrics, University of Pennsylvania, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kevin","family":"Dysart","sequence":"first","affiliation":[{"name":"Division of Neonatology, Department of Pediatrics, University of Pennsylvania, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brenda","family":"Waber","sequence":"first","affiliation":[{"name":"Division of Neonatology, Department of Pediatrics, University of Pennsylvania, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ursula","family":"Nawab","sequence":"first","affiliation":[{"name":"Division of Neonatology, Department of Pediatrics, University of Pennsylvania, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Huayan","family":"Zhang","sequence":"first","affiliation":[{"name":"Division of Neonatology, Department of Pediatrics, University of Pennsylvania, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Erik","family":"Jensen","sequence":"additional","affiliation":[{"name":"Division of Neonatology, Department of Pediatrics, University of Pennsylvania, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2017,4,21]]},"container-title":["American Journal of Perinatology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/s-0037-1602419.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,12,19]],"date-time":"2017-12-19T07:40:59Z","timestamp":1513669259000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/s-0037-1602419"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,4,21]]},"references-count":0,"journal-issue":{"issue":"12","published-online":{"date-parts":[[2017,9,28]]},"published-print":{"date-parts":[[2017,10]]}},"URL":"https:\/\/doi.org\/10.1055\/s-0037-1602419","relation":{},"ISSN":["0735-1631","1098-8785"],"issn-type":[{"value":"0735-1631","type":"print"},{"value":"1098-8785","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,4,21]]}}}