{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,18]],"date-time":"2026-04-18T18:15:45Z","timestamp":1776536145734,"version":"3.51.2"},"reference-count":0,"publisher":"Georg Thieme Verlag KG","issue":"08","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Thorac cardiovasc Surg"],"published-print":{"date-parts":[[2017,12]]},"abstract":"<jats:p>\n            Background\u2003To study the effect of tricuspid valve repair\/replacement on outcomes of patients with reduced systolic right ventricular function.<\/jats:p><jats:p>\n            Methods\u2003Between January 2012 and July 2016, 191 patients with isolated tricuspid valve regurgitation and\/or in combination with other valve diseases were enrolled into this retrospective study. We compared early postoperative outcomes (i.e., 30 days after surgery) between patients' cohort with a preoperative reduced (i.e., at least moderately) versus normal (or mildly reduced) right ventricular function as defined by means of preoperative echocardiography.<\/jats:p><jats:p>\n            Results\u2003A total of 82 (43%) patients had preoperatively reduced right ventricle function with tricuspid annular plane systolic excursion (TAPSE) of 13.3\u2009\u00b1\u20093.3 versus 20.2\u2009\u00b1\u20094.9\u2009mm (p\u2009&lt;\u20090.001). Ring annuloplasty was the most common surgical technique (i.e., 91% in both groups). Time of procedure (317\u2009\u00b1\u2009123 vs. 262\u2009\u00b1\u200988 minutes, p\u2009&lt;\u20090.01) and time on cardiopulmonary bypass (163\u2009\u00b1\u200977 vs. 143\u2009\u00b1\u200957 minutes, p\u2009=\u20090.036) were significantly longer in patients with impaired right ventricular function. Postoperative lactate (3.5\u2009\u00b1\u20093 vs. 2\u2009\u00b1\u20091 mmol\/L, p\u2009=\u20090.001) and dose of catecholamines (epinephrine, 0.07\u2009\u00b1\u20090.15 vs. 0.013\u2009\u00b1\u20090.02 \u00b5g\/kg\/min, p\u2009=\u20090.001; norepinephrine, 0.18\u2009\u00b1\u20090.23 vs. 0.07\u2009\u00b1\u20090.09 \u00b5g\/kg\/min, p\u2009=\u20090.007) were also higher in this group. Postoperative rate of low cardiac output syndrome (10 vs. 27%, p\u2009=\u20090.005) and early mortality (n\u2009=\u20092 vs. n\u2009=\u20099, p\u2009=\u20090.018) were significantly increased in patients with reduced right ventricular function. Previous cardiac operation (p\u2009=\u20090.045), preoperative higher number of acute decompensations of heart failure (p\u2009&lt;\u20090.001), reduced right ventricular function (p\u2009=\u20090.018), postoperative low cardiac output syndrome (p\u2009&lt;\u20090.001), and renal replacement therapy (p\u2009&lt;\u20090.001) were identified as risk factors for early mortality. Echocardiography at discharge revealed tricuspid valve regurgitation grade of 0.9\u2009\u00b1\u20090.7 versus 0.7\u2009\u00b1\u20090.6 (p\u2009=\u20090.052) and TAPSE of 12\u2009\u00b1\u20093 versus 15\u2009\u00b1\u20095\u2009mm (p\u2009=\u20090.026) in patients with reduced right ventricular function. The New York Heart Association (NYHA) class improved to 1.7\u2009\u00b1\u20090.7 versus 1.3\u2009\u00b1\u20091 (p\u2009&lt;\u20090.001) in this group of patients.<\/jats:p><jats:p>\n            Conclusion\u2003Tricuspid valve repair\/replacement effectively eliminated severe tricuspid regurgitation and improved clinical signs of heart failure. Although mortality and morbidity were increased in the group with reduced right ventricular function, even these patients benefitted from improved functional status and right ventricular systolic function early postoperatively.<\/jats:p>","DOI":"10.1055\/s-0037-1604450","type":"journal-article","created":{"date-parts":[[2017,8,25]],"date-time":"2017-08-25T22:56:22Z","timestamp":1503701782000},"page":"617-625","source":"Crossref","is-referenced-by-count":34,"title":["Comparison of Outcomes of Tricuspid Valve Surgery in Patients with Reduced and Normal Right Ventricular Function"],"prefix":"10.1055","volume":"65","author":[{"given":"Evaldas","family":"Girdauskas","sequence":"first","affiliation":[{"name":"Department of Cardiovascular Surgery, University Heart Center Hamburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexander","family":"Bernhardt","sequence":"first","affiliation":[{"name":"Department of Cardiovascular Surgery, University Heart Center Hamburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christoph","family":"Sinning","sequence":"first","affiliation":[{"name":"Department of General and Interventional Cardiology Surgery, University Heart Center Hamburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hermann","family":"Reichenspurner","sequence":"first","affiliation":[{"name":"Department of Cardiovascular Surgery, University Heart Center Hamburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bjoern","family":"Sill","sequence":"first","affiliation":[{"name":"Department of Cardiovascular Surgery, University Heart Center Hamburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Irina","family":"Subbotina","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, University Heart Center Hamburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2017,8,25]]},"container-title":["The Thoracic and Cardiovascular Surgeon"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/s-0037-1604450.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,12,20]],"date-time":"2017-12-20T07:01:22Z","timestamp":1513753282000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/s-0037-1604450"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,8,25]]},"references-count":0,"journal-issue":{"issue":"08","published-online":{"date-parts":[[2017,12,1]]},"published-print":{"date-parts":[[2017,12]]}},"URL":"https:\/\/doi.org\/10.1055\/s-0037-1604450","relation":{},"ISSN":["0171-6425","1439-1902"],"issn-type":[{"value":"0171-6425","type":"print"},{"value":"1439-1902","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,8,25]]}}}