{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T22:14:51Z","timestamp":1787004891597,"version":"build-2736575974"},"reference-count":34,"publisher":"Federa\u00e7\u00e3o das Associa\u00e7\u00f5es de Ginecologia e Obstetr\u00edcia","issue":"09","license":[{"start":{"date-parts":[[2017,8,4]],"date-time":"2017-08-04T00:00:00Z","timestamp":1501804800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rev Bras Ginecol Obstet"],"published-print":{"date-parts":[[2017,9]]},"abstract":"<jats:p>Objective\u2003To define transvaginal ultrasound reference ranges for uterine cervix measurements according to gestational age (GA) in low-risk pregnancies.<\/jats:p>\n                  <jats:p>Methods\u2003Cohort of low-risk pregnant women undergoing transvaginal ultrasound exams every 4 weeks, comprising measurements of the cervical length and volume, the transverse and anteroposterior diameters of the cervix, and distance from the entrance of the uterine artery into the cervix until the internal os. The inter- and intraobserver variabilities were assessed with the linear correlation coefficient and the Student t-test. Within each period of GA, 2.5, 10, 50, 90 and 97.5 percentiles were estimated, and the variation by GA was assessed with analysis of variance for dependent samples. Mean values and Student t-test were used to compare the values stratified by control variables.<\/jats:p>\n                  <jats:p>Results\u2003After confirming the high reproducibility of the method, 172 women followed in this cohort presented a reduction in cervical length, with an increase in volume and in the anteroposterior and transverse diameters during pregnancy. Smaller cervical lengths were associated with younger age, lower parity, and absence of previous cesarean section (C-section).<\/jats:p>\n                  <jats:p>Conclusion\u2003In the studied population, we observed cervical length shortening throughout pregnancy, suggesting a physiological reduction mainly in the vaginal portion of the cervix. In order to better predict preterm birth, cervical insufficiency and premature rupture of membranes, reference curves and specific cut-off values need to be validated.<\/jats:p>","DOI":"10.1055\/s-0037-1605556","type":"journal-article","created":{"date-parts":[[2017,8,4]],"date-time":"2017-08-04T18:34:37Z","timestamp":1501871677000},"page":"443-452","source":"Crossref","is-referenced-by-count":9,"title":["Reference Ranges for Ultrasonographic Measurements of the Uterine Cervix in Low-Risk Pregnant Women"],"prefix":"10.61622","volume":"39","author":[{"given":"Kleber Cursino","family":"Andrade","sequence":"additional","affiliation":[{"name":"Departament of Gynecology e Obstetrics, Faculdade de Ci\u00eancias M\u00e9dicas, Universidade Estadual de Campinas, Campinas, SP, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tha\u00edsa Guedes","family":"Bortoletto","sequence":"additional","affiliation":[{"name":"Departament of Gynecology e Obstetrics, Faculdade de 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Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rodolfo Carvalho","family":"Pacagnella","sequence":"additional","affiliation":[{"name":"Departament of Gynecology e Obstetrics, Faculdade de Ci\u00eancias M\u00e9dicas, Universidade Estadual de Campinas, Campinas, SP, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9 Guilherme","family":"Cecatti","sequence":"additional","affiliation":[{"name":"Departament of Gynecology e Obstetrics, Faculdade de Ci\u00eancias M\u00e9dicas, Universidade Estadual de Campinas, Campinas, SP, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"47794","published-online":{"date-parts":[[2017,8,4]]},"reference":[{"issue":"S 01","key":"ref2","doi-asserted-by":"crossref","first-page":"S2","DOI":"10.1186\/1742-4755-10-S1-S2","article-title":"Born too soon: the global epidemiology of 15 million preterm births","volume":"10","author":"H Blencowe","year":"2013","journal-title":"Reprod 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Miller","year":"2015","journal-title":"Obstet Gynecol"},{"issue":"05","key":"ref21","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1046\/j.1469-0705.1998.12050304.x","article-title":"Cervical length at 23 weeks of gestation: relation to demographic characteristics and previous obstetric history","volume":"12","author":"V C Heath","year":"1998","journal-title":"Ultrasound Obstet Gynecol"},{"issue":"06","key":"ref22","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1002\/jcu.1870160604","article-title":"Ultrasonography in the detection of cervical incompetency","volume":"16","author":"M Podobnik","year":"1988","journal-title":"J Clin Ultrasound"},{"issue":"03","key":"ref23","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1046\/j.0960-7692.2001.525.x","article-title":"Cervical length and spontaneous prematurity: laying the foundation for future interventional randomized trials for the short cervix","volume":"18","author":"E R 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