{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,4]],"date-time":"2026-06-04T14:24:01Z","timestamp":1780583041280,"version":"3.54.1"},"reference-count":21,"publisher":"Federa\u00e7\u00e3o das Associa\u00e7\u00f5es de Ginecologia e Obstetr\u00edcia","issue":"11","license":[{"start":{"date-parts":[[2017,9,25]],"date-time":"2017-09-25T00:00:00Z","timestamp":1506297600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rev Bras Ginecol Obstet"],"published-print":{"date-parts":[[2017,11]]},"abstract":"<jats:p>\n            Objective\u2003To investigate the clinical and sonographic parameters associated with adverse fetal outcomes in patients with congenital parvovirus B19 infection managed by intrauterine transfusion.<\/jats:p><jats:p>\n            Methods\u2003This was a single-center retrospective study conducted from January 2005 to December 2016 that assessed patients with singleton pregnancies with fetal parvovirus infection confirmed by a polymerase chain reaction of the amniotic fluid or fetal blood samples who underwent at least one intrauterine transfusion. The maternal characteristics, sonographic findings and parameters related to intrauterine transfusion were compared between the two groups (recovery\/non-recovery), who were categorized based on fetal response after in-utero transfusions. Progression to fetal death or delivery without fetal recovery after the transfusions was considered non-recovery and categorized as an adverse outcome.<\/jats:p><jats:p>\n            Results\u2003The final analysis included ten singleton pregnancies: seven of which were categorized into the recovery group and three of which into the non-recovery group. The baseline characteristics were similar between the groups. All fetuses were hydropic at the time of diagnosis. No significant differences related to sonographic or intrauterine transfusion parameters were identified between the groups; however, the non-recovery group tended to have an increased number of sonographic markers and lower fetal hemoglobin and platelet levels before the transfusion.<\/jats:p><jats:p>\n            Conclusion\u2003We were unable to firmly establish the clinical or sonographic parameters associated with adverse fetal outcomes in patients with parvovirus infection managed with intrauterine transfusions; however, edema, placental thickening and oligohydramnios may indicate greater fetal compromise and, subsequently, adverse outcomes. However, further studies are necessary, mainly due to the small number of cases analyzed in the present study.<\/jats:p>","DOI":"10.1055\/s-0037-1606859","type":"journal-article","created":{"date-parts":[[2017,9,25]],"date-time":"2017-09-25T22:43:00Z","timestamp":1506379380000},"page":"596-601","source":"Crossref","is-referenced-by-count":6,"title":["Parameters Associated with Adverse Fetal Outcomes in Parvovirus B19 Congenital Infection"],"prefix":"10.61622","volume":"39","author":[{"given":"Isabela Karine Rodrigues","family":"Agra","sequence":"additional","affiliation":[{"name":"Hospital das Cl\u00ednicas - Department of Gynecology and Obstetrics, Obstetrics Discipline, Universidade de S\u00e3o Paulo, S\u00e3o Paulo, S\u00e3o Paulo, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio Gomes","family":"Amorim Filho","sequence":"additional","affiliation":[{"name":"Hospital das Cl\u00ednicas - Department of Gynecology and Obstetrics, Obstetrics Discipline, Universidade de S\u00e3o Paulo, S\u00e3o Paulo, S\u00e3o Paulo, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lawrence Hsu","family":"Lin","sequence":"additional","affiliation":[{"name":"Hospital das Cl\u00ednicas - Department of Gynecology and Obstetrics, Obstetrics Discipline, Universidade de S\u00e3o Paulo, S\u00e3o Paulo, S\u00e3o Paulo, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sckarlet Ernandes","family":"Biancolin","sequence":"additional","affiliation":[{"name":"Hospital das Cl\u00ednicas - Department of Gynecology and Obstetrics, Obstetrics Discipline, Universidade de S\u00e3o Paulo, S\u00e3o Paulo, S\u00e3o Paulo, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rossana Pulcineli Vieira","family":"Francisco","sequence":"additional","affiliation":[{"name":"Hospital das Cl\u00ednicas - Department of Gynecology and Obstetrics, Obstetrics Discipline, Universidade de S\u00e3o Paulo, S\u00e3o Paulo, 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