{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,11]],"date-time":"2026-07-11T13:18:38Z","timestamp":1783775918853,"version":"3.55.0"},"reference-count":0,"publisher":"Georg Thieme Verlag KG","issue":"03","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Neurol Surg A Cent Eur Neurosurg"],"published-print":{"date-parts":[[2018,5]]},"abstract":"<jats:p>\n            Objective\u2003Few studies have compared transsphenoidal endoscopic (TE) and transsphenoidal microscopic (TM) techniques for the treatment of craniopharyngiomas.<\/jats:p><jats:p>\n            Design\u2003We performed a systematic review of published series. The results were stratified in two time periods from 1995 to 2016.<\/jats:p><jats:p>\n            Results\u2003A total of 48 articles and 1,186 patients met the inclusion criteria. Overall, 60% of endoscopic cases were supradiaphragmatic, and 76% of microsurgical cases were infradiaphragmatic. Mean tumor size was 3 cm and 2.4 cm in the TE and TM series, respectively (p\u2009=\u20090.008). Total resection rate was similar (66%) between TE and TM. Considering the surgical outcome for different tumor locations, total resection rate was slightly higher in the TE for supradiaphragmatic lesions (59% versus 42.5%; p\u2009=\u20090.26). Recurrence rate was higher in the endoscopic series (21.7% versus 12%). Mortality and the overall complication rates were similar (p\u2009=\u20090.84). However, hydrocephalus (7.6%) and cognitive dysfunction (15.8%) were more common in TE, and meningitis (6%) and endocrinologic complications were more common in the TM series. In the past 6 years, the rate of cerebrospinal fluid leak in TE was significantly lower (13%) and was comparable between TE and TM.<\/jats:p><jats:p>\n            Conclusion\u2003Both techniques appear comparable for infradiaphragmatic lesions; however, TE seems to yield better results for supradiaphragmatic tumors. In conclusion, more complex lesions with difficult locations can be effectively treated with endoscopic surgery.<\/jats:p>","DOI":"10.1055\/s-0037-1607195","type":"journal-article","created":{"date-parts":[[2017,12,1]],"date-time":"2017-12-01T23:47:47Z","timestamp":1512172067000},"page":"247-256","source":"Crossref","is-referenced-by-count":16,"title":["Endoscopic and Microscopic Transsphenoidal Surgery of Craniopharyngiomas: A Systematic Review of Surgical Outcomes Over Two Decades"],"prefix":"10.1055","volume":"79","author":[{"given":"Matteo","family":"Zoli","sequence":"first","affiliation":[{"name":"Department of Neurosurgery, Ospedale Bellaria Carlo Alberto Pizzardi Neurochirurgia, Bologna, Emilia-Romagna, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Diego","family":"Mazzatenta","sequence":"first","affiliation":[{"name":"Department of Neurosurgery, Ospedale Bellaria Carlo Alberto Pizzardi Neurochirurgia, Bologna, Emilia-Romagna, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jamie","family":"Gompel","sequence":"first","affiliation":[{"name":"Department of Neurologic Surgery, Mayo Clinic, Rochester, Minnesota, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Federico","family":"Cagnazzo","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Universit\u00e0 degli Studi di Pisa, Pisa, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2017,12,1]]},"container-title":["Journal of Neurological Surgery Part A: Central European Neurosurgery"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/s-0037-1607195.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,7,23]],"date-time":"2018-07-23T09:07:49Z","timestamp":1532336869000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/s-0037-1607195"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,12,1]]},"references-count":0,"journal-issue":{"issue":"03","published-online":{"date-parts":[[2018,4,6]]},"published-print":{"date-parts":[[2018,5]]}},"URL":"https:\/\/doi.org\/10.1055\/s-0037-1607195","relation":{},"ISSN":["2193-6315","2193-6323"],"issn-type":[{"value":"2193-6315","type":"print"},{"value":"2193-6323","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,12,1]]}}}