{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T12:38:23Z","timestamp":1791463103113,"version":"4.3.4"},"reference-count":0,"publisher":"Georg Thieme Verlag KG","issue":"05","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Amer J Perinatol"],"published-print":{"date-parts":[[2018,4]]},"abstract":"<jats:p>\n            Objective\u2003This article aims to compare the composite maternal and neonatal morbidities (CMM and CNM, respectively) between macrosomic (\u22654,000 g) and nonmacrosomic (&lt;4,000 g) newborns among women with diabetes mellitus (DM).<\/jats:p><jats:p>\n            Methods\u2003Maternal demographic and peripartum outcome data (N\u2009=\u20091,260) were collected from a retrospective cohort. CMM included chorioamnionitis\/endometritis, wound infection, shoulder dystocia, eclampsia, pulmonary edema, admission for hypoglycemia, 3rd\/4th degree perineal laceration, and death. CNM included 5-minute Appearance, Pulse, Grimace, Activity and Respiration (APGAR) score of &lt;4, neonatal intensive care unit (NICU) admission, respiratory distress syndrome, mechanical ventilation, intraventricular hemorrhage grade III\/IV, necrotizing enterocolitis stage II\/III, hypoglycemia, hypocalcemia, bronchopulmonary dysplasia, sepsis, seizures, hyperbilirubinemia, and death. Multivariable Poisson regression models with robust error variance were used to calculate adjusted relative risk (aRR) and 95% confidence interval (CI).<\/jats:p><jats:p>\n            Results\u2003The study population consisted of 967 subjects, including 854 (88.3%) nonmacrosomic and 113 (11.7%) macrosomic infants. After adjustment, the risk of CMM was higher among macrosomic deliveries (aRR\u2009=\u20094.08, 95% CI\u2009=\u20092.45\u20136.80). The risk of CNM was also higher among macrosomic deliveries (aRR\u2009=\u20091.77, 95% CI\u2009=\u20091.39\u20132.24). Macrosomia was associated with an increased risk in NICU admission, hypoglycemia, and hyperbilirubinemia.<\/jats:p><jats:p>\n            Conclusion\u2003Among DM deliveries, macrosomia was associated with a fourfold higher risk of CMM and almost twofold higher risk of CNM.<\/jats:p>","DOI":"10.1055\/s-0037-1608811","type":"journal-article","created":{"date-parts":[[2017,11,28]],"date-time":"2017-11-28T23:33:07Z","timestamp":1511911987000},"page":"515-520","source":"Crossref","is-referenced-by-count":20,"title":["Morbidity Associated with Fetal Macrosomia among Women with Diabetes Mellitus"],"prefix":"10.1055","volume":"35","author":[{"given":"Amy","family":"O'Neil Dudley","sequence":"first","affiliation":[{"name":"Division of Maternal-Fetal Medicine, Department of Obstetrics, Gynecology, and Reproductive Sciences, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, Texas"},{"name":"Department of Family Medicine, Texas A&M College of Medicine, Bryan, Texas"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hector","family":"Mendez-Figueroa","sequence":"first","affiliation":[{"name":"Division of Maternal-Fetal Medicine, Department of Obstetrics, Gynecology, and Reproductive Sciences, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, Texas"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Viviana","family":"Ellis","sequence":"first","affiliation":[{"name":"Division of Maternal-Fetal Medicine, Department of Obstetrics, Gynecology, and Reproductive Sciences, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, Texas"},{"name":"Department of Obstetrics and Gynecology, The University of Texas Medical Branch, Galveston, Texas"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Han-Yang","family":"Chen","sequence":"first","affiliation":[{"name":"Division of Maternal-Fetal Medicine, Department of Obstetrics, Gynecology, and Reproductive Sciences, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, Texas"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suneet","family":"Chauhan","sequence":"first","affiliation":[{"name":"Division of Maternal-Fetal Medicine, Department of Obstetrics, Gynecology, and Reproductive Sciences, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, Texas"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zachary","family":"Jenner","sequence":"additional","affiliation":[{"name":"Division of Maternal-Fetal Medicine, Department of Obstetrics, Gynecology, and Reproductive Sciences, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, Texas"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2017,11,28]]},"container-title":["American Journal of Perinatology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/s-0037-1608811.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,3,29]],"date-time":"2018-03-29T22:36:14Z","timestamp":1522362974000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/s-0037-1608811"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,11,28]]},"references-count":0,"journal-issue":{"issue":"05","published-online":{"date-parts":[[2018,3,29]]},"published-print":{"date-parts":[[2018,4]]}},"URL":"https:\/\/doi.org\/10.1055\/s-0037-1608811","relation":{},"ISSN":["0735-1631","1098-8785"],"issn-type":[{"value":"0735-1631","type":"print"},{"value":"1098-8785","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,11,28]]}}}