{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T23:41:20Z","timestamp":1790811680059,"version":"4.1.0"},"reference-count":0,"publisher":"Georg Thieme Verlag KG","issue":"08","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Amer J Perinatol"],"published-print":{"date-parts":[[2018,7]]},"abstract":"<jats:p>\n            Background\u2003There is a lack of definite consensus on indications for initiating antibiotics in neonates with meconium aspiration syndrome (MAS), instigating researchers to search for a biomarker that can help differentiate MAS from MAS with bacterial infection.<\/jats:p><jats:p>\n            Objective\u2003Our primary objective was to compare serum procalcitonin (PCT) levels in full-term vigorous neonates having MAS with or without bacterial infection.<\/jats:p><jats:p>\n            Materials and Methods\u2003Seventy term vigorous neonates with diagnosis of MAS were enrolled. Blood samples were taken for sepsis screen, C-reactive protein (CRP), PCT, and blood culture at 6\u2009\u00b1\u20092 hours of respiratory distress. Neonates were categorized into group 1 (MAS without bacterial infection) and group 2 (MAS with bacterial infection) based on blood culture. The duration of our study was 18 months.<\/jats:p><jats:p>\n            Results\u2003Mean\u2009\u00b1\u2009standard deviation PCT level was 2.52\u2009\u00b1\u20093.99 in group 1 and 2.71\u2009\u00b1\u20094.22 in group 2, which was comparable. At cutoff of 0.1 ng\/mL, PCT had a sensitivity of 90% and specificity of 8% in detecting bacterial infection. Mean total leukocyte count, absolute neutrophil count, immature to total leucocyte ratio, microerythrocyte sedimentation rate, and CRP were comparable.<\/jats:p><jats:p>\n            Conclusion\u2003Though PCT is an early and reliable marker of neonatal infection, the levels were increased in neonates with MAS irrespective of the presence of bacterial infection.<\/jats:p>","DOI":"10.1055\/s-0037-1615793","type":"journal-article","created":{"date-parts":[[2017,12,29]],"date-time":"2017-12-29T18:37:39Z","timestamp":1514572659000},"page":"769-773","source":"Crossref","is-referenced-by-count":7,"title":["Procalcitonin as Predictor of Bacterial Infection in Meconium Aspiration Syndrome"],"prefix":"10.1055","volume":"35","author":[{"given":"Mahendiran","family":"K.","sequence":"first","affiliation":[{"name":"Department of Pediatrics, University College of Medical Sciences and Guru Tegh Bahadur Hospital, Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Faridi","sequence":"first","affiliation":[{"name":"Department of Pediatrics, University College of Medical Sciences and Guru Tegh Bahadur Hospital, Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N.","family":"Singh","sequence":"first","affiliation":[{"name":"Department of Microbiology, University College of Medical Sciences and Guru Tegh Bahadur Hospital, Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Prerna","family":"Batra","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, University College of Medical Sciences and Guru Tegh Bahadur Hospital, Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2017,12,29]]},"container-title":["American Journal of Perinatology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/s-0037-1615793.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,6,18]],"date-time":"2018-06-18T18:44:03Z","timestamp":1529347443000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/s-0037-1615793"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,12,29]]},"references-count":0,"journal-issue":{"issue":"08","published-online":{"date-parts":[[2018,6,18]]},"published-print":{"date-parts":[[2018,7]]}},"URL":"https:\/\/doi.org\/10.1055\/s-0037-1615793","relation":{},"ISSN":["0735-1631","1098-8785"],"issn-type":[{"value":"0735-1631","type":"print"},{"value":"1098-8785","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,12,29]]}}}