{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,19]],"date-time":"2026-02-19T01:15:31Z","timestamp":1771463731152,"version":"3.50.1"},"reference-count":0,"publisher":"Georg Thieme Verlag KG","issue":"11","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Amer J Perinatol"],"published-print":{"date-parts":[[2018,9]]},"abstract":"<jats:p>\n            Background\u2003Although supplemental oxygen (SO2) is routinely administered to laboring gravidas, benefits and harms are not well studied.<\/jats:p><jats:p>\n            Objective\u2003This article compares strategies of liberal versus indicated SO2 therapy during labor on cesarean delivery (CD) rate and neonatal outcomes.<\/jats:p><jats:p>\n            Study Design\u2003A controlled, before-and-after trial of laboring women with term, singleton pregnancies. During an initial 8-week period, maternal SO2 was administered at the discretion of the provider followed by an 8-week period where SO2 was to be given only for protocol indications.<\/jats:p><jats:p>\n            Results\u2003Our study included 844 women. There was no difference in number of women receiving SO2 (53% liberal vs. 50% indicated; p\u2009=\u20090.33). For those receiving SO2, there was no difference in SO2 duration (median, 89 minutes [interquartile range, 42\u2013172] vs. 87 minutes [36\u2013152]; p\u2009=\u20090.42). There were no differences in overall CD rate (20% vs. 17%; p\u2009=\u20090.70), CD for nonreassuring fetal status, or use of intrauterine resuscitative measures. There were more 5-minute APGAR\u2009&lt;\u20097 in the indicated group, but no difference in umbilical artery pH\u2009&lt;\u20097.1 or neonatal intensive care unit (NICU) admission.<\/jats:p><jats:p>\n            Conclusion\u2003Approximately half of women receive SO2 intrapartum regardless of a strategy of liberal or indicated oxygen use. There were no clinically significant differences in outcomes between strategies.<\/jats:p>","DOI":"10.1055\/s-0038-1639357","type":"journal-article","created":{"date-parts":[[2018,3,26]],"date-time":"2018-03-26T22:36:59Z","timestamp":1522103819000},"page":"1057-1064","source":"Crossref","is-referenced-by-count":5,"title":["Liberal versus Indicated Maternal Oxygen Supplementation in Labor: A Before-and-After Trial"],"prefix":"10.1055","volume":"35","author":[{"given":"Sean","family":"Blackwell","sequence":"first","affiliation":[{"name":"Division of Maternal Fetal Medicine, Department of Obstetrics, Gynecology and Reproductive Sciences, University of Texas Health Science Center at Houston, McGovern Medical School, Houston, Texas"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mesk","family":"Alrais","sequence":"first","affiliation":[{"name":"Division of Maternal Fetal Medicine, Department of Obstetrics, Gynecology and Reproductive Sciences, University of Texas Health Science Center at Houston, McGovern Medical School, Houston, Texas"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Farah","family":"Amro","sequence":"first","affiliation":[{"name":"Department of Obstetrics, Gynecology and Reproductive Sciences, University of Texas Health Science Center at Houston, McGovern Medical School, Houston, Texas"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rachel","family":"Wiley","sequence":"first","affiliation":[{"name":"Department of Obstetrics, Gynecology and Reproductive Sciences, University of Texas Health Science Center at Houston, McGovern Medical School, Houston, Texas"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patricia","family":"Heale","sequence":"first","affiliation":[{"name":"Children's Memorial Hermann Hospital, The Women's Center, Labor and Delivery, Houston, Texas"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria","family":"Hutchinson","sequence":"first","affiliation":[{"name":"Division of Maternal Fetal Medicine, Department of Obstetrics, Gynecology and Reproductive Sciences, University of Texas Health Science Center at Houston, McGovern Medical School, Houston, Texas"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Baha","family":"Sibai","sequence":"first","affiliation":[{"name":"Division of Maternal Fetal Medicine, Department of Obstetrics, Gynecology and Reproductive Sciences, University of Texas Health Science Center at Houston, McGovern Medical School, Houston, Texas"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nana-Ama","family":"Ankumah","sequence":"additional","affiliation":[{"name":"Division of Maternal Fetal Medicine, Department of Obstetrics, Gynecology and Reproductive Sciences, University of Texas Health Science Center at Houston, McGovern Medical School, Houston, Texas"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2018,3,26]]},"container-title":["American Journal of Perinatology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/s-0038-1639357.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,8,31]],"date-time":"2018-08-31T22:40:15Z","timestamp":1535755215000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/s-0038-1639357"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,3,26]]},"references-count":0,"journal-issue":{"issue":"11","published-online":{"date-parts":[[2018,8,31]]},"published-print":{"date-parts":[[2018,9]]}},"URL":"https:\/\/doi.org\/10.1055\/s-0038-1639357","relation":{},"ISSN":["0735-1631","1098-8785"],"issn-type":[{"value":"0735-1631","type":"print"},{"value":"1098-8785","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,3,26]]}}}