{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T02:25:03Z","timestamp":1792635903463,"version":"4.5.0"},"reference-count":0,"publisher":"Georg Thieme Verlag KG","issue":"06","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Neurol Surg A Cent Eur Neurosurg"],"published-print":{"date-parts":[[2018,11]]},"abstract":"<jats:p>\n            Background\u2003Anterior cervical fusion (ACF) with autologous bone was reported\u2009&gt;\u200950 years ago. The continuous development of materials with elastic properties close to that of the cortical bone improves induction of osteogenesis and simplifies the technique of interbody fusion. To determine the safety and efficiency of stand-alone trabecular metal (TM) (or porous tantalum) cages for ACF, we performed a retrospective analysis of 88 consecutive patients with one-level or two-level degenerative disk disease (DDD) causing cervical myelopathy treated by interbody fusion with stand-alone TM cages.<\/jats:p><jats:p>\n            Materials and Methods\u2003During a 65-month period, 88 consecutive patients had ACF at 105 levels between C3 and C7. All surgeries involved one- or two-segmental DDD producing mild or severe cervical spine myelopathy, in 31 patients (35.2%), associated with unilateral or bilateral radiculopathy. We implanted all disk spaces with unfilled TM trapezoidal cages (Zimmer Biomet Spine, Broomfield, Colorado, United States).<\/jats:p><jats:p>\n            Results\u2003At a mean follow-up of 31 months (range: 12\u201365 months), 95.4% of patients had a good to excellent outcome, with subjective and objective improvement of myelopathy; the result was fair in two and poor in two other patients. Radicular pain and\/or any deficits disappeared in 84 patients (95.4%) complaining of preoperative myeloradiculopathy. The fusion rate was 68.2% at 6 months and 100% at 1 year. Device fragmentation was never observed. In two cases, a second operation with removal of TM cages, corpectomy, expansion cages, and plating was necessary.<\/jats:p><jats:p>\n            Conclusions\u2003TM cages appear to be safe and efficient for ACF in DDD patients with myelopathy. To confirm our preliminary impressions, larger studies with long-term follow-up are necessary.<\/jats:p>","DOI":"10.1055\/s-0038-1642008","type":"journal-article","created":{"date-parts":[[2018,7,23]],"date-time":"2018-07-23T04:35:56Z","timestamp":1532320556000},"page":"496-501","source":"Crossref","is-referenced-by-count":7,"title":["Anterior Cervical Fusion with Stand-alone Trabecular Metal Cages to Treat Cervical Myelopathy Caused by Degenerative Disk Disease. Observations in 88 Cases with Minimum 12-month Follow-up"],"prefix":"10.1055","volume":"79","author":[{"given":"Raffaelino","family":"Roperto","sequence":"first","affiliation":[{"name":"Department of Neurosurgery, San Filippo Neri Hospital of Roma, via Martinotti 20 Roma, Italy, Roma 00135, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guglielmo","family":"Cacciotti","sequence":"first","affiliation":[{"name":"Department of Neurosurgery, San Filippo Neri Hospital of Roma, via Martinotti 20 Roma, Italy, Roma 00135, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesco","family":"Calvosa","sequence":"first","affiliation":[{"name":"Department of Neurosurgery, San Filippo Neri Hospital of Roma, via Martinotti 20 Roma, Italy, Roma 00135, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luciano","family":"Mastronardi","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, San Filippo Neri Hospital of Roma, via Martinotti 20 Roma, Italy, Roma 00135, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2018,6,14]]},"container-title":["Journal of Neurological Surgery Part A: Central European Neurosurgery"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/s-0038-1642008.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,10,15]],"date-time":"2018-10-15T18:31:27Z","timestamp":1539628287000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/s-0038-1642008"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,6,14]]},"references-count":0,"journal-issue":{"issue":"06","published-online":{"date-parts":[[2018,10,15]]},"published-print":{"date-parts":[[2018,11]]}},"URL":"https:\/\/doi.org\/10.1055\/s-0038-1642008","relation":{},"ISSN":["2193-6315","2193-6323"],"issn-type":[{"value":"2193-6315","type":"print"},{"value":"2193-6323","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,6,14]]}}}