{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,7,18]],"date-time":"2024-07-18T19:40:08Z","timestamp":1721331608569},"reference-count":26,"publisher":"Federa\u00e7\u00e3o das Associa\u00e7\u00f5es de Ginecologia e Obstetr\u00edcia","issue":"04","license":[{"start":{"date-parts":[[2018,5,10]],"date-time":"2018-05-10T00:00:00Z","timestamp":1525910400000},"content-version":"vor","delay-in-days":39,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rev Bras Ginecol Obstet"],"published-print":{"date-parts":[[2018,4]]},"abstract":"<jats:p>\n            Objective\u2003To evaluate the use of tocolysis in cases of preterm birth due to spontaneous preterm labor in a Brazilian sample.<\/jats:p><jats:p>\n            Methods\u2003A sample of 1,491 women with preterm birth due to spontaneous preterm labor were assessed, considering treatment with tocolysis or expectant management, according to gestational age at birth (&lt; 34 weeks and 34 to 36\u2009+\u20096 weeks) and drugs prescribed. The study took place in 20 Brazilian hospitals from April 2011 to July 2012. Bivariate analyses were conducted to evaluate associations with sociodemographic and obstetric characteristics and odds ratios with their respective 95% confidence intervals were estimated for maternal and neonatal outcomes.<\/jats:p><jats:p>\n            Results\u2003A total of 1,491 cases of preterm birth were considered. Tocolysis was performed in 342 cases (23%), 233 of which (68.1%) were delivered before 34 weeks. Within the expectant management group, 73% was late preterm and with more advanced labor at the time of admission. The most used drugs were calcium channel blockers (62.3%), followed by betamimetics (33%). Among the subjects in the tocolysis group, there were more neonatal and maternal complications (majority non-severe) and an occurrence of corticosteroid use that was 29 higher than in the expectant management group.<\/jats:p><jats:p>\n            Conclusion\u2003Tocolysis is favored in cases of earlier labor and also among those with less than 34 weeks of gestation, using preferably calcium channel blockers, with success in achieving increased corticosteroid use. Tocolysis, in general, was related to higher maternal and neonatal complication rates, which may be due to the baseline difference between cases at admission. However, these results should raise awareness to tocolysis use.<\/jats:p>","DOI":"10.1055\/s-0038-1642025","type":"journal-article","created":{"date-parts":[[2018,5,10]],"date-time":"2018-05-10T22:34:10Z","timestamp":1525991650000},"page":"171-179","source":"Crossref","is-referenced-by-count":1,"title":["Tocolysis among Women with Preterm Birth: Associated Factors and Outcomes from a Multicenter Study in Brazil"],"prefix":"10.61622","volume":"40","author":[{"given":"Tabata Zumpano","family":"Dias","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, School of Medical Sciences, Universidade Estadual de Campinas, Campinas, SP, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mariana Lacerda","family":"Fava","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, School of Medical Sciences, Universidade Estadual de Campinas, Campinas, SP, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Renato","family":"Passini J\u00fanior","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, School of Medical Sciences, Universidade Estadual de Campinas, Campinas, SP, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jose Guilherme","family":"Cecatti","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, School of Medical Sciences, Universidade Estadual de Campinas, Campinas, SP, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ricardo Porto","family":"Tedesco","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Faculdade de Medicina de Jundia\u00ed, Jundia\u00ed, SP, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giuliane Jesus","family":"Lajos","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, School of Medical Sciences, Universidade Estadual de Campinas, Campinas, SP, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patricia Moretti","family":"Rehder","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, School of Medical Sciences, Universidade Estadual de Campinas, Campinas, SP, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marcelo Luis","family":"Nomura","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, School of Medical Sciences, Universidade Estadual de Campinas, Campinas, SP, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paulo Fanti","family":"Oliveira","sequence":"additional","affiliation":[{"name":"Unit of Statistics, School of Medical Sciences, Universidade Estadual de Campinas, Campinas, SP, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria Laura","family":"Costa","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, School of Medical Sciences, Universidade Estadual de Campinas, Campinas, SP, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"47794","published-online":{"date-parts":[[2018,5,10]]},"reference":[{"issue":"S 01","key":"ref1","doi-asserted-by":"crossref","first-page":"S2","DOI":"10.1186\/1742-4755-10-S1-S2","article-title":"Born too soon: the global epidemiology of 15 million preterm births","volume":"10","author":"H Blencowe","year":"2013","journal-title":"Reprod Health"},{"issue":"11","key":"ref2","doi-asserted-by":"crossref","first-page":"e0141852","DOI":"10.1371\/journal.pone.0141852","article-title":"The growing trend of moderate preterm births: an ecological study in one region of Brazil","volume":"10","author":"R R Oliveira","year":"2015","journal-title":"PLoS 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