{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,3]],"date-time":"2026-04-03T22:12:35Z","timestamp":1775254355432,"version":"3.50.1"},"reference-count":155,"publisher":"Georg Thieme Verlag KG","issue":"03","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nuklearmedizin"],"published-print":{"date-parts":[[2018,6]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title>\n                  <jats:p>In der aktualisierten und erweiterten S1-Leitlinie zur Lungenszintigraphie werden die Vorz\u00fcge der Methode beim Nachweis der akuten Lungenembolie (LE) in der Lungenperipherie (subsegmentale LE), bei subakuten und chronischen Grunderkrankungen der Lunge, sowie beim Nachweis der chronischen LE (CTEPH) herausgestellt. Methode der Wahl ist die Ventilations\/Perfusions(V\/P)-SPECT oder V\/P-SPECT\/CT mit nochmals gesteigerter Spezifit\u00e4t. Aufgrund der hohen Sensitivit\u00e4t wird, um eine \u00dcbertherapie zu vermeiden, ein Schwellenwert eingef\u00fchrt (V\/P-mismatch in mindestens einem Segment oder zwei Subsegmenten). Im Falle eines ver\u00e4nderten Therapieverhaltens (nur Observation anstelle Antikoagulation) kann der Schwellenwert entfallen. Zur klinisch-therapeutischen Wertigkeit von subsementalen LE werden neue Daten pr\u00e4sentiert, die Kapitel offene Fragen wurden erweitert. Die weiteren Indikationen f\u00fcr V\/P-SPECT (Nebendiagnosen, Anomalien der Lungenperfusion, Voraussage der postoperativen Lungenfunktion) werden mit neueren Daten hinterlegt.<\/jats:p>","DOI":"10.1055\/s-0038-1649553","type":"journal-article","created":{"date-parts":[[2018,10,19]],"date-time":"2018-10-19T10:48:08Z","timestamp":1539946088000},"page":"74-91","source":"Crossref","is-referenced-by-count":1,"title":["Lungenszintigraphie (Version 3)"],"prefix":"10.1055","volume":"57","author":[{"given":"Carl","family":"Sch\u00fcmichen","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matthias","family":"Schmidt","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas","family":"Krause","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2018,6,5]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1177\/1076029614559772","article-title":"Wells Score and Poor Outcomes Among Adult Patients With Subsegmental Pulmonary Embolism: A Cohort Study","volume":"21","author":"F Angriman","year":"2015","journal-title":"Clin Appl Thromb Hemost"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"704","DOI":"10.1097\/MNM.0000000000000114","article-title":"Detection of pulmonary embolism during pregnancy: comparing radiation doses of CTPA and pulmonary scintigraphy","volume":"35","author":"SA Astani","year":"2014","journal-title":"Nucl Med Commun"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"e120","DOI":"10.1016\/j.ejrad.2012.09.019","article-title":"Imaging of nonthrombotic pulmonary embolism: biological materials, nonbiological materials, and foreign bodies","volume":"82","author":"AG Bach","year":"2013","journal-title":"Eur J Radiol"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"e0148728.","DOI":"10.1371\/journal.pone.0148728","article-title":"30-Day Mortality in Acute Pulmonary Embolism: Prognostic Value of Clinical Scores and Anamnestic Features","volume":"11","author":"AG Bach","year":"2016","journal-title":"PLoS One"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1007\/s00259-013-2612-7","article-title":"Good clinical practice in pulmonary embolism diagnosis: where do we stand today?","volume":"41","author":"M Bajc","year":"2014","journal-title":"Eur J Nucl Med Mol Imaging"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"1432","DOI":"10.1007\/s00259-013-2425-8","article-title":"Perfusion SPECT in patients with suspected pulmonary embolism","volume":"40","author":"M Bajc","year":"2013","journal-title":"Eur J Nucl Med Mol Imaging"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"1528","DOI":"10.1007\/s00259-009-1169-y","article-title":"EANM guidelines for ventilation\/perfusion scintigraphy : Part 2. 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