{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,12]],"date-time":"2026-07-12T03:13:11Z","timestamp":1783825991825,"version":"3.55.0"},"reference-count":0,"publisher":"Georg Thieme Verlag KG","issue":"09","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J reconstr Microsurg"],"published-print":{"date-parts":[[2018,11]]},"abstract":"<jats:p>\n            Aim\u2003To achieve a favorable risk\u2013benefit balance for hand transplantation, an immunomodulatory protocol was developed in the laboratory and translated to clinical application.<\/jats:p><jats:p>\n            Methods\u2003Following donor bone marrow infusion into transplant recipients, hand and arm allografts have been maintained on low-dose tacrolimus monotherapy.<\/jats:p><jats:p>\n            Results\u2003Good-to-excellent functional recovery has been achieved in patients compliant with medication and therapy, thus restoring autonomous and productive lives.<\/jats:p><jats:p>\n            Conclusion\u2003The risk-benefit balance can be tilted in favor of the hand transplant recipients by using an immunomodulatory protocol with minimum immunosuppression.<\/jats:p>","DOI":"10.1055\/s-0038-1651524","type":"journal-article","created":{"date-parts":[[2018,5,18]],"date-time":"2018-05-18T22:49:47Z","timestamp":1526683787000},"page":"683-684","source":"Crossref","is-referenced-by-count":10,"title":["From Auto- to Allotransplantation: Immunomodulatory Protocol for Hand and Arm Transplantation"],"prefix":"10.1055","volume":"34","author":[{"given":"Jaimie","family":"Shores","sequence":"first","affiliation":[{"name":"Department of Plastic and Reconstructive Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gerald","family":"Brandacher","sequence":"first","affiliation":[{"name":"Department of Plastic and Reconstructive Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"W.","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Plastic and Reconstructive Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2018,5,18]]},"container-title":["Journal of Reconstructive Microsurgery"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/s-0038-1651524.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,10,9]],"date-time":"2018-10-09T22:41:26Z","timestamp":1539124886000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/s-0038-1651524"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,5,18]]},"references-count":0,"journal-issue":{"issue":"09","published-online":{"date-parts":[[2018,10,9]]},"published-print":{"date-parts":[[2018,11]]}},"URL":"https:\/\/doi.org\/10.1055\/s-0038-1651524","relation":{},"ISSN":["0743-684X","1098-8947"],"issn-type":[{"value":"0743-684X","type":"print"},{"value":"1098-8947","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,5,18]]}}}