{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,23]],"date-time":"2025-07-23T12:33:37Z","timestamp":1753274017019},"reference-count":0,"publisher":"Georg Thieme Verlag KG","issue":"03","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Homeopathy"],"published-print":{"date-parts":[[2018,8]]},"abstract":"<jats:p>\n            Background\u2003Contact dermatitis (CD) is a frequently occurring medical condition, for which Vinca minor (VM) is one of the recommended homeopathic medicines. However, the symptoms indicating this medicine have not yet been assessed systematically. Likelihood ratio (LR), based on Bayesian statistics, may yield better estimation of a medicine's indication than the existing method of entry of symptoms into materia medica and repertories.<\/jats:p><jats:p>\n            Methods\u2003We investigated LRs of four CD symptoms of VM: (1) great sensitiveness of skin, with redness and soreness from slightest rubbing; (2) weeping eczema with foul, thick crusts; (3) itching amelioration in open air; and (4) CD of scalp. An observational, prospective, patient-outcome study was conducted in five different practice settings on 390 CD patients over 18 months using three outcomes\u2014Glasgow Homeopathic Hospital Outcome Scale (GHHOS), Scoring Atopic Dermatitis (SCORAD), and Dermatology Life Quality Index (DLQI), assessed at baseline, after 3 and 6 months. The LR of each of the four symptoms was estimated as per the patient-rated outcomes on GHHOS.<\/jats:p><jats:p>\n            Results\u2003Seventy-four VM and 316 non-VM cases were analyzed. Estimated LRs were as follows: symptom 1, 1.29 (95% confidence interval [CI]: 0.65 to 2.60); symptom 2, 1.48 (95% CI: 0.80 to 2.74); symptom 3, 1.70 (95% CI: 0.94 to 3.07); symptom 4, 1.36 (95% CI: 0.74 to 2.51). There were statistically significant reductions in SCORAD and DLQI scores over 3 and 6 months.<\/jats:p><jats:p>\n            Conclusion\u2003There was insufficient evidence to attribute any of the four assessed symptoms clearly to VM. Though non-significant, a high LR was observed for \u201citching amelioration in open air\u201d (symptom 3). Symptoms in the homeopathic materia medica for VM are perhaps over-represented. More research of this nature is warranted.<\/jats:p>","DOI":"10.1055\/s-0038-1654713","type":"journal-article","created":{"date-parts":[[2018,5,21]],"date-time":"2018-05-21T22:39:44Z","timestamp":1526942384000},"page":"209-217","source":"Crossref","is-referenced-by-count":5,"title":["Assessment of Likelihood Ratio for Four Contact Dermatitis Symptoms of Vinca Minor"],"prefix":"10.1055","volume":"107","author":[{"given":"Chaturbhuja","family":"Nayak","sequence":"first","affiliation":[{"name":"Department of Homoeopathic Materia Medica, Homoeopathy University, Jaipur, Rajasthan, India"},{"name":"Central Council for Research in Homoeopathy, Janakpuri, New Delhi, Delhi, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lex","family":"Rutten","sequence":"first","affiliation":[{"name":"VHAN, Dutch Association of Homeopathic Physicians, Breda, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Munmun","family":"Koley","sequence":"first","affiliation":[{"name":"Independent Researcher, Hooghly, West Bengal, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Subhranil","family":"Saha","sequence":"first","affiliation":[{"name":"Independent Researcher, Howrah, West Bengal, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mousumi","family":"Roy","sequence":"first","affiliation":[{"name":"AYUSH Health Department, Govt. Homoeo Dispensary, Chhura, Gariaband, Chhattisgarh, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sk","family":"Abbas","sequence":"first","affiliation":[{"name":"Department of RBSK, Kulai Rural Hospital, Panchla, Howrah, West Bengal, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Simantini","family":"Ghosh","sequence":"first","affiliation":[{"name":"Department of Surgery, Mahesh Bhattacharyya Homoeopathic Medical College and Hospital, Howrah, West Bengal, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Suman","family":"Halder","sequence":"first","affiliation":[{"name":"Private Practitioner and Independent Researcher, Palashipara, Nadia, West Bengal, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ghulam","family":"Wani","sequence":"first","affiliation":[{"name":"Department of Health & Medical Education, District Hospitals, Baramullah and Handwara, Jammu & Kashmir, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anaitulah","family":"Mir","sequence":"first","affiliation":[{"name":"Department of Health & Medical Education, District Hospitals, Baramullah and Handwara, Jammu & Kashmir, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Showket","family":"Bhat","sequence":"first","affiliation":[{"name":"Department of Health & Medical Education, District Hospitals, Baramullah and Handwara, Jammu & Kashmir, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Suman","family":"Bagchi","sequence":"additional","affiliation":[{"name":"Department of Homoeopathic Materia Medica, Homoeopathy University, Jaipur, Rajasthan, India"},{"name":"Department of Forensic Medicine & Toxicology, C. L. Chouksey Memorial Homoeopathic Medical College, Hospital and Research Center, Bilaspur, Chhattisgarh, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2018,5,21]]},"container-title":["Homeopathy"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/s-0038-1654713.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,8,7]],"date-time":"2018-08-07T22:34:17Z","timestamp":1533681257000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/s-0038-1654713"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,5,21]]},"references-count":0,"journal-issue":{"issue":"03","published-online":{"date-parts":[[2018,8,7]]},"published-print":{"date-parts":[[2018,8]]}},"URL":"https:\/\/doi.org\/10.1055\/s-0038-1654713","relation":{},"ISSN":["1475-4916","1476-4245"],"issn-type":[{"value":"1475-4916","type":"print"},{"value":"1476-4245","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,5,21]]}}}