{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,18]],"date-time":"2026-04-18T04:23:44Z","timestamp":1776486224966,"version":"3.51.2"},"reference-count":0,"publisher":"Georg Thieme Verlag KG","issue":"14","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Amer J Perinatol"],"published-print":{"date-parts":[[2018,12]]},"abstract":"<jats:p>\n            Objective\u2003To assess whether assisted reproductive technology (ART) is associated with increased risk of adverse perinatal outcomes in triplet gestations compared with spontaneous conception.<\/jats:p><jats:p>\n            Study Design\u2003Secondary analysis of a multicenter randomized trial for the prevention of preterm birth in multiple gestations. Triplets delivered at\u2009\u2265\u200924 weeks were studied. The primary outcome was the rate of composite neonatal morbidity (CNM) that included one or more of the following: bronchopulmonary dysplasia, respiratory distress syndrome, necrotizing enterocolitis, culture proven sepsis, pneumonia, retinopathy of prematurity, intraventricular hemorrhage, periventricular leukomalacia, or perinatal death.<\/jats:p><jats:p>\n            Results\u2003There were 381 triplets (127 women) of which 89 patients conceived via ART and 38 patients spontaneously. Women with ART were more likely to be older, Caucasian, married, nulliparous, have higher level of education, and develop pre-eclampsia. Spontaneously conceived triplets were more likely to delivery at an earlier gestation (31.2\u2009\u00b1\u20093.5 vs 32.8\u2009\u00b1\u20092.7 weeks) (p\u2009=\u20090.009) with a lower birth weight (p\u2009&lt;\u20090.001). After adjusting for confounders, no differences were noted in culture proven sepsis, perinatal death, CNM, respiratory distress syndrome, or Apgar\u2009score &lt;\u20097 at 5 minutes. All remaining perinatal outcomes were similar.<\/jats:p><jats:p>\n            Conclusion\u2003Triplets conceived by ART had similar perinatal outcomes compared with spontaneously conceived triplets.<\/jats:p>","DOI":"10.1055\/s-0038-1660457","type":"journal-article","created":{"date-parts":[[2018,6,8]],"date-time":"2018-06-08T23:07:33Z","timestamp":1528499253000},"page":"1388-1393","source":"Crossref","is-referenced-by-count":9,"title":["The Relationship of Assisted Reproductive Technology on Perinatal Outcomes in Triplet Gestations"],"prefix":"10.1055","volume":"35","author":[{"given":"Jaimin","family":"Shah","sequence":"additional","affiliation":[{"name":"Department of Obstetrics, Gynecology and Reproductive Sciences, McGovern Medical School at The University of Texas Health Science Center at Houston, Houston, Texas"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tania","family":"Roman","sequence":"additional","affiliation":[{"name":"Division of Maternal and Fetal Medicine, The University of Texas Health Science Center at San Antonio, San Antonio, Texas"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Oscar","family":"Viteri","sequence":"additional","affiliation":[{"name":"Division of Maternal Fetal Medicine, McGovern Medical School at The University of Texas Health Science Center at Houston, Houston, Texas"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ziad","family":"Haidar","sequence":"additional","affiliation":[{"name":"Division of Maternal Fetal Medicine, McGovern Medical School at The University of Texas Health Science Center at Houston, Houston, Texas"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alejandra","family":"Ontiveros","sequence":"additional","affiliation":[{"name":"Division of Maternal Fetal Medicine, McGovern Medical School at The University of Texas Health Science Center at Houston, Houston, Texas"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Baha","family":"Sibai","sequence":"additional","affiliation":[{"name":"Division of Maternal Fetal Medicine, McGovern Medical School at The University of Texas Health Science Center at Houston, Houston, Texas"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2018,6,8]]},"container-title":["American Journal of Perinatology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/s-0038-1660457.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,6]],"date-time":"2019-05-06T20:01:34Z","timestamp":1557172894000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/s-0038-1660457"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,6,8]]},"references-count":0,"journal-issue":{"issue":"14","published-online":{"date-parts":[[2018,11,20]]},"published-print":{"date-parts":[[2018,12]]}},"URL":"https:\/\/doi.org\/10.1055\/s-0038-1660457","relation":{},"ISSN":["0735-1631","1098-8785"],"issn-type":[{"value":"0735-1631","type":"print"},{"value":"1098-8785","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,6,8]]}}}