{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,5]],"date-time":"2026-06-05T05:27:50Z","timestamp":1780637270590,"version":"3.54.1"},"reference-count":0,"publisher":"Georg Thieme Verlag KG","issue":"05","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Eur J Pediatr Surg"],"published-print":{"date-parts":[[2019,10]]},"abstract":"<jats:p>\n            Introduction\u2003Recent publications have questioned the sensitivity of suction rectal biopsy (SRB) for diagnosis of Hirschsprung's disease (HD) in newborns. A recent European survey reported that 39% of pediatric surgeons performed full-thickness transanal biopsies due to concerns about the accuracy of SRB. We sought to examine our contemporary SRB experience in infants.<\/jats:p><jats:p>\n            Materials and Methods\u2003A review was performed (2007\u20132016) of patients under 6 months of age who had a SRB at our children's hospital. The cohort was subdivided by postmenstrual age at time of SRB: preterm (&lt; 40 weeks, A), term neonate (40\u201344 weeks, B), and infant (&gt; 44 weeks, C). The pathology reports from endorectal pull-through were used as gold standard confirmation. One-year follow-up of patients with negative SRB was used to confirm accurate diagnosis.<\/jats:p><jats:p>\n            Results\u2003A total of 153 patients met the criteria and a total of 159 SRBs (&lt; 2,500\u2009g; n\u2009=\u200926) were performed (A\u2009=\u200960, B\u2009=\u200958, C\u2009=\u200935). Forty-three patients were diagnosed with HD (A\u2009=\u200925, B\u2009=\u200915, C\u2009=\u20093). A second SRB was performed in 6 (3.9%) patients due to inadequate tissue (A\u2009=\u20092, B\u2009=\u20092, C\u2009=\u20092) with HD diagnosed in 5. No complications occurred. Sensitivity and specificity of SRB was 100% in all age groups. Half of the patients with a negative SRB had at least 1\u2009year follow-up, with none subsequently diagnosed with HD.<\/jats:p><jats:p>\n            Conclusion\u2003SRB results in adequate tissue for evaluation of HD in nearly all patients less than 6 months of age on the first attempt and is highly accurate in the preterm and newborn infants. No complications occurred, even among infants less than 2,500 g.<\/jats:p>","DOI":"10.1055\/s-0038-1667040","type":"journal-article","created":{"date-parts":[[2018,8,1]],"date-time":"2018-08-01T18:53:29Z","timestamp":1533149609000},"page":"425-430","source":"Crossref","is-referenced-by-count":20,"title":["Accuracy of Suction Rectal Biopsy for Diagnosis of Hirschsprung's Disease in Neonates"],"prefix":"10.1055","volume":"29","author":[{"given":"Ashley Rebekah","family":"Allen","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery, School of Medicine, University of Utah Hospital, Salt Lake City, Utah, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angelica R.","family":"Putnam","sequence":"additional","affiliation":[{"name":"Department of Pathology, University of Utah School of Medicine, Salt Lake City, Utah, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angela P.","family":"Presson","sequence":"additional","affiliation":[{"name":"Division of Epidemiology, University of Utah Hospital, Salt Lake City, Utah, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chelsea McCarty","family":"Allen","sequence":"additional","affiliation":[{"name":"Division of Epidemiology, University of Utah Hospital, Salt Lake City, Utah, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Douglas C.","family":"Barnhart","sequence":"additional","affiliation":[{"name":"Division of Pediatric Surgery, Primary Children's Hospital, University of Utah, Salt Lake City, Utah, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael D.","family":"Rollins","sequence":"additional","affiliation":[{"name":"Division of Pediatric Surgery, Primary Children's Hospital, University of Utah, Salt Lake City, Utah, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2018,8,1]]},"container-title":["European Journal of Pediatric Surgery"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/s-0038-1667040.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,10,21]],"date-time":"2019-10-21T18:31:28Z","timestamp":1571682688000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/s-0038-1667040"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,8,1]]},"references-count":0,"journal-issue":{"issue":"05","published-online":{"date-parts":[[2019,10,21]]},"published-print":{"date-parts":[[2019,10]]}},"URL":"https:\/\/doi.org\/10.1055\/s-0038-1667040","relation":{},"ISSN":["0939-7248","1439-359X"],"issn-type":[{"value":"0939-7248","type":"print"},{"value":"1439-359X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,8,1]]}}}