{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,6,13]],"date-time":"2025-06-13T15:27:23Z","timestamp":1749828443054},"reference-count":25,"publisher":"Federa\u00e7\u00e3o das Associa\u00e7\u00f5es de Ginecologia e Obstetr\u00edcia","issue":"09","license":[{"start":{"date-parts":[[2018,9,19]],"date-time":"2018-09-19T00:00:00Z","timestamp":1537315200000},"content-version":"vor","delay-in-days":18,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rev Bras Ginecol Obstet"],"published-print":{"date-parts":[[2018,9]]},"abstract":"<jats:p>\n            Objective\u2003To analyze the use of the measurement of uterine cervix length (MUCL) and the fetal fibronectin (fFN) rapid test as predictors of preterm delivery (PTD) in symptomatic pregnant women assisted at the Santa Casa de Miseric\u00f3rdia de Sobral Maternity Hospital.<\/jats:p><jats:p>\n            Methods\u2003This was a prospective and analytic study involving 53 parturients assisted between September of 2015 and July of 2016; the participants were between 24 and 34 weeks of gestational age (GA) and presented complaints related to preterm labor (PTL) prodromes. Vaginal secretion was collected for fFN testing, and the MUCL was obtained via transvaginal ultrasonography.<\/jats:p><jats:p>\n            Results\u2003A total of 58.49% of the subjects showed MUCL\u2009&lt;\u200925\u2009mm, and 41.51% were positive in the fFN rapid test. A total of 48 patients were followed-up until their delivery date, and 54.17% resulted in PTL. The relative risk (RR) for PTD in patients with MUCL\u2009&lt;\u200925\u2009mm was 1.83 (p\u2009=\u20090.09, 0.99\u20133.36, 95% confidence interval [CI]), with a mean time before delivery of 2.98 weeks. Based on fFN positive results, the RR was 3.50 (p\u2009=\u20090.002, 1.39\u20138.79, 95%CI) and the mean time until delivery was 1.94 weeks. The RR was 2.70 (p\u2009=\u20090.002, 1.08\u20136.72, 95%CI) when both tests were used. The RR of PTD within 48 hours, and 7 and 14 days were, respectively, 1.30 (p\u2009=\u20090.11, 95% CI 1.02\u20131.67), 1.43 (p\u2009=\u20090.12, 95% CI % 0.99\u20132.06), and 2.03 (p\u2009=\u20090.008, 95% CI 1.26\u20133.27), when based on the MUCL, and 1.75 (p\u2009=\u20090.0006, 95% CI 1.20\u20132.53), 2.88 (p\u2009=\u20090.0001, 95% CI, 1.57\u20135.31), and 3.57 (p\u2009=\u20090.0002, 95% CI 1.63\u20137.81) when based on positive fFN results. The RR at 48 hours and 7 and 14 days considering both tests was 1.74 (p\u2009=\u20090.0001, 95% CI 1.14\u20132.64), 2.22 (p\u2009=\u20090.0001, 95% CI 1.22\u20134.04), and 2.76 (p\u2009=\u20090.0002, 95% CI 1.27\u20135.96), respectively.<\/jats:p><jats:p>\n            Conclusion\u2003In symptomatic pregnant women, we concluded that the MUCL\u2009&lt;\u200925\u2009mm associated with positive fFN rapid test indicate increased the risk for PTD. Further studies with larger sample sizes could contribute in supporting the results presented in the current study.<\/jats:p>","DOI":"10.1055\/s-0038-1667185","type":"journal-article","created":{"date-parts":[[2018,9,19]],"date-time":"2018-09-19T22:44:36Z","timestamp":1537397076000},"page":"507-512","source":"Crossref","is-referenced-by-count":2,"title":["Risk Assessment for Preterm Delivery using the Fetal Fibronectin Test Associated with the Measurement of Uterine Cervix Length in Symptomatic Pregnant Women"],"prefix":"10.61622","volume":"40","author":[{"given":"Tadeu Rodriguez de Carvalho","family":"Pinheiro Filho","sequence":"additional","affiliation":[{"name":"Gynecology and Obstetrics Residency Program, Santa Casa de Miseric\u00f3rdia de Sobral, Sobral, CE, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vanessa Rocha","family":"Pessoa","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Universidade Federal do Cear\u00e1, Sobral, CE, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thaisa de Sousa","family":"Lima","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Universidade Federal do Cear\u00e1, Sobral, CE, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marcela Melo de","family":"Castro","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Universidade Federal do Cear\u00e1, Sobral, CE, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jos\u00e9 Juvenal","family":"Linhares","sequence":"additional","affiliation":[{"name":"Gynecology and Obstetrics Residency Program, Santa Casa de Miseric\u00f3rdia de Sobral, Sobral, CE, Brazil"},{"name":"Faculty of Medicine, Universidade Federal do Cear\u00e1, Sobral, CE, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"47794","published-online":{"date-parts":[[2018,9,19]]},"reference":[{"issue":"01","key":"ref1","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1016\/j.ijgo.2014.10.011","article-title":"Best practice in maternal-fetal medicine","volume":"128","year":"2015","journal-title":"Int J Gynaecol Obstet"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1016\/S0140-6736(08)60108-7","article-title":"Primary, secondary, and tertiary interventions to reduce the morbidity and mortality of preterm birth","volume":"371","author":"J D Iams","year":"2008","journal-title":"Lancet"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/S0140-6736(08)60074-4","article-title":"Epidemiology and causes of preterm birth","volume":"371","author":"R L Goldenberg","year":"2008","journal-title":"Lancet"},{"issue":"02","key":"ref4","doi-asserted-by":"crossref","first-page":"e0148244","DOI":"10.1371\/journal.pone.0148244","article-title":"The burden of provider-initiated preterm birth and associated factors: evidence from the Brazilian Multicenter Study on Preterm Birth (EMIP)","volume":"11","author":"R T Souza","year":"2016","journal-title":"PLoS One"},{"issue":"01","key":"ref5","doi-asserted-by":"crossref","first-page":"1323","DOI":"10.4238\/2014.February.28.4","article-title":"Fetal fibronectin detection for preterm birth prediction","volume":"13","author":"L Gao","year":"2014","journal-title":"Genet Mol Res"},{"issue":"04","key":"ref6","first-page":"203","article-title":"[Risk predictors for preterm birth]","volume":"31","author":"R E Bittar","year":"2009","journal-title":"Rev Bras Ginecol Obstet"},{"key":"ref7","first-page":"655","article-title":"Direct determinants of elective preterm birth and neonatal results","volume":"26","author":"E Rades","year":"2004","journal-title":"Rev Bras Ginecol Obstet"},{"key":"ref8","first-page":"633","article-title":"Evaluation of risk for preterm delivery by fetal fibronectin test and measurement of uterine cervix","volume":"22","author":"T A Oliveira","year":"2000","journal-title":"Rev Bras Ginecol Obstet"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1590\/S1519-38292006000200010","article-title":"Preval\u00eancia e fatores associados \u00e0 prematuridade entre gestantes submetidas \u00e0 inibi\u00e7\u00e3o de trabalho de parto prematuro","volume":"6","author":"L C Bezerra","year":"2006","journal-title":"Rev Bras Saude Mater Infant"},{"issue":"12","key":"ref10","first-page":"1027","article-title":"Early cervical length, preterm prelabor and gestational age at delivery. 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