{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T18:37:41Z","timestamp":1787510261557,"version":"build-2736575974"},"reference-count":0,"publisher":"Georg Thieme Verlag KG","issue":"02","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Amer J Perinatol"],"published-print":{"date-parts":[[2019,1]]},"abstract":"<jats:p>Objective\u2003To evaluate the risk of preterm birth in low-risk women with cervical length (CL) \u226425\u2009mm on transvaginal ultrasound (TVUS) managed with vaginal progesterone (VagP) therapy versus cerclage.<\/jats:p>\n                  <jats:p>Study Design\u2003This is a retrospective cohort of women with no prior history of preterm birth or cervical insufficiency and CL\u2009\u2264\u200925\u2009mm on TVUS, managed with either VagP therapy alone or cerclage (with or without VagP). The primary outcome was rate of preterm delivery\u2009&lt;\u200937 weeks gestational age (GA). Secondary outcomes included delivery at\u2009\u2264\u200932 or\u2009\u2264\u200928 weeks GA, premature preterm rupture of membranes, pregnancy latency, GA at delivery, and composite neonatal outcome.<\/jats:p>\n                  <jats:p>Results\u2003Women undergoing cerclage placement (n\u2009=\u200931) were older and had an earlier GA at the time of diagnosis of short cervix compared with women receiving VagP (n\u2009=\u200962). Delivery at\u2009&lt;\u200937 weeks occurred in 21\/62 (33.9%) in the VagP group and 14\/31 (45.2%) in the cerclage group (adjusted odds ratio: 1.72, 95% confidence interval: 0.52, 5.66). There were no differences in secondary outcomes.<\/jats:p>\n                  <jats:p>Conclusion\u2003Cerclage compared with VagP therapy did not decrease risk of preterm birth in women with CL\u2009\u2264\u200925 mm. Further research is needed to determine optimal management in such women given a residual 40% risk of preterm birth despite optimal therapy.<\/jats:p>","DOI":"10.1055\/s-0038-1668547","type":"journal-article","created":{"date-parts":[[2018,8,16]],"date-time":"2018-08-16T00:58:16Z","timestamp":1534381096000},"page":"111-117","source":"Crossref","is-referenced-by-count":9,"title":["Cervical Cerclage versus Vaginal Progesterone for Management of Short Cervix in Low-Risk Women"],"prefix":"10.1055","volume":"36","author":[{"given":"Sarah","family":"Dotters-Katz","sequence":"first","affiliation":[{"name":"Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Duke University, Durham, North Carolina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brenna","family":"Hughes","sequence":"first","affiliation":[{"name":"Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Duke University, Durham, North Carolina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amber","family":"Wood","sequence":"additional","affiliation":[{"name":"Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Duke University, Durham, North Carolina"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2018,8,15]]},"container-title":["American Journal of Perinatology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/s-0038-1668547.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,1,22]],"date-time":"2019-01-22T19:21:42Z","timestamp":1548184902000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/s-0038-1668547"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,8,15]]},"references-count":0,"journal-issue":{"issue":"02","published-online":{"date-parts":[[2019,1,22]]},"published-print":{"date-parts":[[2019,1]]}},"URL":"https:\/\/doi.org\/10.1055\/s-0038-1668547","relation":{},"ISSN":["0735-1631","1098-8785"],"issn-type":[{"value":"0735-1631","type":"print"},{"value":"1098-8785","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,8,15]]}}}