{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T11:28:32Z","timestamp":1780486112124,"version":"3.54.1"},"reference-count":0,"publisher":"Georg Thieme Verlag KG","issue":"01","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Eur J Pediatr Surg"],"published-print":{"date-parts":[[2019,2]]},"abstract":"<jats:p>\n            Aim\u2003The American College of Surgeons has developed a registry, the National Quality Improvement Program Pediatric (NSQIP-P), that provides participating centers with high-quality surgical outcome data for children. Herein, we aimed to analyze for the first time the short-term outcomes of live-born infants with congenital diaphragmatic hernia (CDH) registered on this large North American database.<\/jats:p><jats:p>\n            Methods\u2003During 2015 to 2016, up to 101 participating centers uploaded 95 perioperative data points on the NSQIP-P database for patients that underwent surgical repair of CDH. The demographics, peri-, and post-operative data (up to 30 days following surgical repair) of infants with CDH were reviewed. Binary logistic regression was performed to test associations between risk factors and mortality.<\/jats:p><jats:p>\n            Main Results\u2003There were 432 (61% male) infants, who underwent CDH surgical repair during the study period. The prematurity rate (gestational age\u2009&lt;\u200937 weeks) was 17%. The majority of infants (82%) had cardiac risk factors identified (72% were reported as major\/severe). Extracorporeal membrane oxygenation (ECMO) was employed in 13% of patients prior to surgery. The majority of infants (83%) were ventilated preoperatively, and 34% received inotropes. Median age at surgery was 5 (0\u201374) days. CDH repair was attempted via thoracoscopy in 18% (n\u2009=\u200979) infants, but with a high rate of conversion to open surgery (n\u2009=\u200932, 41%). The postoperative 30-day mortality rate was 9%. At binary logistic regression, major cardiac risk factors (odds ratio [OR], 1.7 [0.9\u20133.2], p\u2009=\u20090.095), Appearance, Pulse, Grimace, Activity, and Respiration at 1 minute (OR, 0.7 per unit [0.5\u20130.8], p\u2009&lt;\u20090.005), and birth weight (OR, 0.5 per kg [0.2\u20131.0], p\u2009&lt;\u20090.05) were retained in the final model as significantly associated with mortality.<\/jats:p><jats:p>\n            Conclusion\u2003This is the first report on CDH outcomes from the NSQIP-P database. Utilization of ECMO was low compared with single-center studies from North America. The early postoperative mortality rate of babies with CDH considered suitable for surgery remains high.<\/jats:p>","DOI":"10.1055\/s-0038-1668563","type":"journal-article","created":{"date-parts":[[2018,8,21]],"date-time":"2018-08-21T19:01:40Z","timestamp":1534878100000},"page":"062-067","source":"Crossref","is-referenced-by-count":10,"title":["First Population-Based Report of Infants with Congenital Diaphragmatic Hernia: 30-Day Outcomes from the American College of Surgeons National Quality Improvement Program"],"prefix":"10.1055","volume":"29","author":[{"given":"Elke","family":"Zani-Ruttenstock","sequence":"first","affiliation":[{"name":"Division of General and Thoracic Surgery, The Hospital for Sick Children, Toronto, Ontario, Canada"},{"name":"Department of Surgery, University of Toronto, Toronto, Ontario, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simon","family":"Eaton","sequence":"first","affiliation":[{"name":"UCL Great Ormond Street Institute of Child Health, London, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Annie","family":"Fecteau","sequence":"first","affiliation":[{"name":"Division of General and Thoracic Surgery, The Hospital for Sick Children, Toronto, Ontario, Canada"},{"name":"Department of Surgery, University of Toronto, Toronto, Ontario, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Augusto","family":"Zani","sequence":"additional","affiliation":[{"name":"Division of General and Thoracic Surgery, The Hospital for Sick Children, Toronto, Ontario, Canada"},{"name":"Department of Surgery, University of Toronto, Toronto, Ontario, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2018,8,21]]},"container-title":["European Journal of Pediatric Surgery"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/s-0038-1668563.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,1,17]],"date-time":"2019-01-17T18:37:44Z","timestamp":1547750264000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/s-0038-1668563"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,8,21]]},"references-count":0,"journal-issue":{"issue":"01","published-online":{"date-parts":[[2019,1,17]]},"published-print":{"date-parts":[[2019,2]]}},"URL":"https:\/\/doi.org\/10.1055\/s-0038-1668563","relation":{},"ISSN":["0939-7248","1439-359X"],"issn-type":[{"value":"0939-7248","type":"print"},{"value":"1439-359X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,8,21]]}}}