{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,28]],"date-time":"2026-07-28T04:36:57Z","timestamp":1785213417660,"version":"3.55.0"},"reference-count":0,"publisher":"Georg Thieme Verlag KG","issue":"05","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Amer J Perinatol"],"published-print":{"date-parts":[[2019,4]]},"abstract":"<jats:p>\n            Objective\u2003To determine the short-term outcomes (abnormal brain magnetic resonance imaging [MRI]\/death) in infants born with a 10-minute Apgar score of 0 who received therapeutic hypothermia and compare them with infants with higher scores.<\/jats:p><jats:p>\n            Study Design\u2003This is a retrospective review of 293 neonates (gestational age\u2009\u2265\u200935 weeks) born between November 2006 and October 2015 admitted with hypoxic-ischemic encephalopathy who received therapeutic hypothermia. Results of brain MRIs were assessed by the basal ganglia\/watershed scoring system. Short-term outcomes were compared between infants with Apgar scores of 0, 1 to 4, and \u22655 at 10 minutes.<\/jats:p><jats:p>\n            Results\u2003Eight of 17 infants (47%) with an Apgar of 0 at 10 minutes survived, having 4 (24%) without abnormalities on the brain MRI and 7 (41%) without severe abnormalities. There was no significant difference in the combined outcomes of \u201cdeath\/abnormal MRI\u201d and \u201cdeath\/severe abnormalities on the MRI\u201d between infants with Apgar scores of 0 and 1 to 4. Follow-up data were available for six of eight surviving infants, and none had moderate or severe neurodevelopmental impairment.<\/jats:p><jats:p>\n            Conclusion\u2003In the cooling era, 47% of infants with no audible heart rate at 10 minutes and who were admitted to the neonatal intensive care unit survived; 24% without abnormalities on the brain MRI and 41% without severe abnormalities.<\/jats:p>","DOI":"10.1055\/s-0038-1670637","type":"journal-article","created":{"date-parts":[[2018,9,12]],"date-time":"2018-09-12T22:41:20Z","timestamp":1536792080000},"page":"545-554","source":"Crossref","is-referenced-by-count":19,"title":["Apgar Scores at 10 Minutes and Outcomes in Term and Late Preterm Neonates with Hypoxic-Ischemic Encephalopathy in the Cooling Era"],"prefix":"10.1055","volume":"36","author":[{"given":"Marina","family":"Ayrapetyan","sequence":"additional","affiliation":[{"name":"Department of Pediatrics\/Neonatology, Thomas Jefferson University\/Nemours, Philadelphia, Pennsylvania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kiran","family":"Talekar","sequence":"additional","affiliation":[{"name":"Department of Radiology, Thomas Jefferson University\/Nemours, Philadelphia, Pennsylvania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kathleen","family":"Schwabenbauer","sequence":"additional","affiliation":[{"name":"Department of Pediatrics\/Neonatology, Thomas Jefferson University\/Nemours, Philadelphia, Pennsylvania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Carola","sequence":"additional","affiliation":[{"name":"Department of Pediatrics\/Neonatology, Thomas Jefferson University\/Nemours, Philadelphia, Pennsylvania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kolawole","family":"Solarin","sequence":"additional","affiliation":[{"name":"Department of Pediatrics\/Neonatology, Thomas Jefferson University\/Nemours, Philadelphia, Pennsylvania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dorothy","family":"McElwee","sequence":"additional","affiliation":[{"name":"Department of Pediatrics\/Neonatology, Thomas Jefferson University\/Nemours, Philadelphia, Pennsylvania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susan","family":"Adeniyi-Jones","sequence":"additional","affiliation":[{"name":"Department of Pediatrics\/Neonatology, Thomas Jefferson University\/Nemours, Philadelphia, Pennsylvania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jay","family":"Greenspan","sequence":"additional","affiliation":[{"name":"Department of Pediatrics\/Neonatology, Thomas Jefferson University\/Nemours, Philadelphia, Pennsylvania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zubair","family":"Aghai","sequence":"additional","affiliation":[{"name":"Department of Pediatrics\/Neonatology, Thomas Jefferson University\/Nemours, Philadelphia, Pennsylvania"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2018,9,12]]},"container-title":["American Journal of Perinatology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/s-0038-1670637.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,4,2]],"date-time":"2019-04-02T22:44:43Z","timestamp":1554245083000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/s-0038-1670637"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,9,12]]},"references-count":0,"journal-issue":{"issue":"05","published-online":{"date-parts":[[2019,4,2]]},"published-print":{"date-parts":[[2019,4]]}},"URL":"https:\/\/doi.org\/10.1055\/s-0038-1670637","relation":{},"ISSN":["0735-1631","1098-8785"],"issn-type":[{"value":"0735-1631","type":"print"},{"value":"1098-8785","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,9,12]]}}}