{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T16:20:55Z","timestamp":1791303655373,"version":"4.1.0"},"reference-count":0,"publisher":"Georg Thieme Verlag KG","issue":"06","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Amer J Perinatol"],"published-print":{"date-parts":[[2019,5]]},"abstract":"<jats:p>\n            Objective\u2003Herein, we measured the concentration of insulinlike growth factor I (IGF-I), IGF-II, leptin, adiponectin, ghrelin, resistin, and visfatin in the umbilical cord blood of newborns categorized as \u201csmall for gestational age\u201d (SGA), \u201cappropriate for gestational age\u201d (AGA), and \u201clarge for gestational age\u201d (LGA). Our aim was to elucidate the link between the levels of these proteins and fetal growth.<\/jats:p><jats:p>\n            Study Design\u2003A total of 96 term infants were included and categorized into three weight categories. Their venous cord blood samples were collected to measure the levels of IGF-I, IGF-II, leptin, adiponectin, ghrelin, resistin, and visfatin.<\/jats:p><jats:p>\n            Results\u2003IGF-I, visfatin, and leptin levels showed significant differences among the groups. Pairwise comparisons showed that adiponectin (p\u2009=\u20090.023), resistin (p\u2009=\u20090.025), and ghrelin (p\u2009=\u20090.005) levels were significantly lower in the SGA group than in the LGA group. Correlation analyses showed a strong association of IGF-1, IGF-II, and leptin levels with birth weight (r\u2009=\u20090.644, p\u2009&lt;\u20090.001; r\u2009=\u20090.441, p\u2009&lt;\u20090.001; and r\u2009=\u20090.404, p\u2009&lt;\u20090.001, respectively).<\/jats:p><jats:p>\n            Conclusion\u2003SGA newborns showed a significantly higher visfatin concentration and lower ghrelin, leptin, resistin, and adiponectin levels than the AGA and LGA newborns did.<\/jats:p>","DOI":"10.1055\/s-0038-1672141","type":"journal-article","created":{"date-parts":[[2018,10,3]],"date-time":"2018-10-03T22:33:47Z","timestamp":1538606027000},"page":"600-608","source":"Crossref","is-referenced-by-count":31,"title":["The Role of Umbilical Cord Blood Concentration of IGF-I, IGF-II, Leptin, Adiponectin, Ghrelin, Resistin, and Visfatin in Fetal Growth"],"prefix":"10.1055","volume":"36","author":[{"given":"Emine","family":"Yalinbas","sequence":"additional","affiliation":[{"name":"Division of Neonatology, Dumlup\u0131nar University School of Medicine, Kutahya, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cigdem","family":"Binay","sequence":"additional","affiliation":[{"name":"Department of Pediatric Endocrinology, Eskisehir Osmangazi University Faculty of Medicine, Eskisehir, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Enver","family":"Simsek","sequence":"additional","affiliation":[{"name":"Department of Pediatric Endocrinology, Eskisehir Osmangazi University Faculty of Medicine, Eskisehir, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mehmet","family":"Aksit","sequence":"additional","affiliation":[{"name":"Division of Neonatology, Eskisehir Osmangazi University Faculty of Medicine, Eskisehir, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2018,10,3]]},"container-title":["American Journal of Perinatology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/s-0038-1672141.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,4,30]],"date-time":"2019-04-30T22:41:38Z","timestamp":1556664098000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/s-0038-1672141"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,10,3]]},"references-count":0,"journal-issue":{"issue":"06","published-online":{"date-parts":[[2019,4,30]]},"published-print":{"date-parts":[[2019,5]]}},"URL":"https:\/\/doi.org\/10.1055\/s-0038-1672141","relation":{},"ISSN":["0735-1631","1098-8785"],"issn-type":[{"value":"0735-1631","type":"print"},{"value":"1098-8785","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,10,3]]}}}