{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,3]],"date-time":"2025-08-03T22:58:15Z","timestamp":1754261895520},"reference-count":0,"publisher":"Georg Thieme Verlag KG","issue":"04","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Neurol Surg B"],"published-print":{"date-parts":[[2019,8]]},"abstract":"<jats:p>\n            Objectives\u2003Endoscopic techniques in pituitary surgery lead to inevitable mucosal loss of the sphenoethmoidal recess and posterior nasal septum in the nasal cavity. There is no other comparative study between primary reconstruction of septal perforation and secondary healing in the literature. The aim of this study is to evaluate postoperative patient morbidity with or without posterior septal perforation in endonasal pituitary surgery by comparing two commonly used techniques: rescue and double nasoseptal flaps.<\/jats:p><jats:p>\n            Design\u2003Prospectively randomized study.<\/jats:p><jats:p>\n            Setting\u2003Tertiary academic center.<\/jats:p><jats:p>\n            Participants\u2003Sixty patients underwent endoscopic endonasal pituitary surgery.<\/jats:p><jats:p>\n            Main Outcomes and Measures\u2003Functional results (breathing) using visual analog scale (VAS), sphenoid sinusitis, presence of synechia, perforation in the posterior septum, and crusting in the sphenoethmoidal recess were assessed.<\/jats:p><jats:p>\n            Results\u2003Pre- and postoperative mean VAS scores were 71.67\u2009\u00b1\u200911.47 and 67.67\u2009\u00b1\u20099.71\u2009mm in the intact septum group and 77.67\u2009\u00b1\u200914.06 and 62.67\u2009\u00b1\u200910.48\u2009mm in the posterior septal perforation group. There was a significant difference between pre- and postoperative VAS values in all groups. There was significant worsening in both groups; worsening in VAS values was much higher in the posterior septal perforation group. In the posterior septal perforation group, much more crusting was seen.<\/jats:p><jats:p>\n            Conclusions\u2003This is the first study to compare the postoperative patient morbidity in endoscopic endonasal pituitary surgery with and without a posterior septal perforation. Reconstruction of the posterior septum along with less mucosal loss yields better postoperative nasal symptom score.<\/jats:p>","DOI":"10.1055\/s-0038-1673695","type":"journal-article","created":{"date-parts":[[2018,11,21]],"date-time":"2018-11-21T00:01:28Z","timestamp":1542758488000},"page":"431-436","source":"Crossref","is-referenced-by-count":7,"title":["Comparison between Rescue Flap and Double Flap Technique"],"prefix":"10.1055","volume":"80","author":[{"given":"Murat","family":"Benzer","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, Ege University School of Medicine, Izmir, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Huseyin","family":"Biceroglu","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Ege University, Izmir, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Murat Samet","family":"Ates","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, Ege University School of Medicine, Izmir, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Isa","family":"Kaya","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, Ege University School of Medicine, Izmir, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Erkin","family":"Ozgiray","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Ege University, Izmir, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rasit","family":"Midilli","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, Ege University School of Medicine, Izmir, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bulent","family":"Karc\u0131","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, Ege University School of Medicine, Izmir, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sercan","family":"Gode","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, Ege University School of Medicine, Izmir, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2018,11,20]]},"container-title":["Journal of Neurological Surgery Part B: Skull Base"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/s-0038-1673695.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,7,16]],"date-time":"2019-07-16T22:43:36Z","timestamp":1563317016000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/s-0038-1673695"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,11,20]]},"references-count":0,"journal-issue":{"issue":"04","published-online":{"date-parts":[[2019,7,16]]},"published-print":{"date-parts":[[2019,8]]}},"URL":"https:\/\/doi.org\/10.1055\/s-0038-1673695","relation":{},"ISSN":["2193-6331","2193-634X"],"issn-type":[{"value":"2193-6331","type":"print"},{"value":"2193-634X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,11,20]]}}}