{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,8]],"date-time":"2026-01-08T18:08:51Z","timestamp":1767895731725,"version":"3.49.0"},"reference-count":0,"publisher":"Georg Thieme Verlag KG","issue":"11","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Amer J Perinatol"],"published-print":{"date-parts":[[2019,9]]},"abstract":"<jats:p>\n            Objective\u2003We sought to examine pathogen distribution and clinical presentation of late-onset sepsis (LOS) at an urban tertiary care center.<\/jats:p><jats:p>\n            Study Design\u2003We performed a retrospective review of all culture-confirmed cases of LOS presenting to our institution from 2013 to 2017. Medical records were evaluated for demographic information, sepsis risk factors, encounter location, and clinical outcome.<\/jats:p><jats:p>\n            Results\u2003We identified 97 cases of LOS, with a median age at diagnosis of 25 days. The most common pathogens were Escherichia coli (22.7%), Staphylococcus aureus (17.5%), coagulase-negative staphylococci (12.4%), and Enterococcus faecalis (12.4%). Infections due to E. coli predominated in the outpatient setting (44%), whereas S. aureus and Gram-negative organisms other than E. coli were more frequently isolated from inpatients (21 and 24%, respectively). Gram-positive organisms were more common in infants delivered through cesarean section (p\u2009=\u20090.002) and were associated with more complications (p\u2009=\u20090.03). Escherichia coli LOS presented at an earlier age than S. aureus (15 vs. 32 days; p\u2009=\u20090.04). Of the 15 cases of meningitis, 40% did not have a positive blood culture.<\/jats:p><jats:p>\n            Conclusion\u2003Pathogen distribution in our population was different from those previously reported, with a higher prevalence of S. aureus. Encounter location and age at presentation varied significantly by pathogen.<\/jats:p>","DOI":"10.1055\/s-0038-1675643","type":"journal-article","created":{"date-parts":[[2018,12,15]],"date-time":"2018-12-15T00:02:20Z","timestamp":1544832140000},"page":"1136-1141","source":"Crossref","is-referenced-by-count":9,"title":["Distribution of Late-Onset Neonatal Sepsis Pathogens Differs in Inpatient and Outpatient Settings"],"prefix":"10.1055","volume":"36","author":[{"given":"Celeste G.","family":"Black","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, New York University School of Medicine, New York, New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Larissa","family":"Tavares","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, New York University School of Medicine, New York, New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anna","family":"Stachel","sequence":"additional","affiliation":[{"name":"Infection Prevention and Control, New York University Langone Health System, New York, New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adam J.","family":"Ratner","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, New York University School of Medicine, New York, New York"},{"name":"Department of Microbiology, New York University School of Medicine, New York, New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tara M.","family":"Randis","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, New York University School of Medicine, New York, New York"},{"name":"Department of Microbiology, New York University School of Medicine, New York, New York"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2018,12,14]]},"container-title":["American Journal of Perinatology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/s-0038-1675643.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,9,6]],"date-time":"2019-09-06T22:39:32Z","timestamp":1567809572000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/s-0038-1675643"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,12,14]]},"references-count":0,"journal-issue":{"issue":"11","published-online":{"date-parts":[[2019,9,6]]},"published-print":{"date-parts":[[2019,9]]}},"URL":"https:\/\/doi.org\/10.1055\/s-0038-1675643","relation":{},"ISSN":["0735-1631","1098-8785"],"issn-type":[{"value":"0735-1631","type":"print"},{"value":"1098-8785","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,12,14]]}}}