{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,4]],"date-time":"2025-10-04T08:08:18Z","timestamp":1759565298288},"reference-count":0,"publisher":"Georg Thieme Verlag KG","issue":"07","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Amer J Perinatol"],"published-print":{"date-parts":[[2019,6]]},"abstract":"<jats:p>\n            Objective\u2003To evaluate outcomes with expectant management of preterm prelabor rupture of membranes (PROM) until 35 weeks versus immediate delivery at \u226534 weeks.<\/jats:p><jats:p>\n            Study Design\u2003This was a multicenter retrospective cohort study of singletons with preterm PROM at &gt;20 weeks from 2011 through 2017. Groups were defined as expectant management until 35 weeks versus immediate delivery at \u226534 weeks. Primary outcome was composite neonatal morbidity: need for respiratory support, culture positive neonatal sepsis, or antibiotic administration for &gt;72 hours. Univariate and general estimating equation models were used with p\u2009&lt;\u20090.05 considered significant.<\/jats:p><jats:p>\n            Results\u2003A total of 280 mother\u2013infant dyads were included. There was no difference in composite neonatal outcome in pregnancies managed with expectant management compared with immediate delivery (43.4 vs. 37.5%; p\u2009=\u20090.32). Those with expectant management had shorter length of neonatal intensive care unit (NICU) admission but higher rates of neonatal antibiotics for\u2009&gt;\u200972 hours, endometritis, and histological chorioamnionitis. There were no cases of fetal demise, neonatal death, or maternal sepsis, and only three cases of neonatal sepsis.<\/jats:p><jats:p>\n            Conclusion\u2003There is no difference in composite neonatal morbidity in pregnancies with preterm PROM managed with expectant management until 35 weeks as compared with immediate delivery at 34 weeks. Expectant management is associated with a decreased length of NICU admission but increased short-term infectious morbidity.<\/jats:p>","DOI":"10.1055\/s-0038-1675647","type":"journal-article","created":{"date-parts":[[2018,12,15]],"date-time":"2018-12-15T18:31:02Z","timestamp":1544898662000},"page":"659-668","source":"Crossref","is-referenced-by-count":4,"title":["Preterm Prelabor Rupture of Membranes: Outcomes with Expectant Management until 34 versus 35 Weeks"],"prefix":"10.1055","volume":"36","author":[{"given":"Tara A.","family":"Lynch","sequence":"additional","affiliation":[{"name":"Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, University of Rochester Medical Center, Rochester, New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Courtney","family":"Olson-Chen","sequence":"additional","affiliation":[{"name":"Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, University of Rochester Medical Center, Rochester, New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sarah","family":"Colihan","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Albany Medical Center, Albany, New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeffrey","family":"Meyers","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, University of Rochester Medical Center, Rochester, New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Conisha","family":"Holloman","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Winnie Palmer Hospital for Women and Babies, Orlando Health, Orlando, Florida"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dongmei","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Clinical and Translational Research, University of Rochester, Rochester, New York"},{"name":"Department of Obstetrics and Gynecology, Department of Public Health Sciences, University of Rochester, Rochester, New York"},{"name":"Department of Public Health Sciences, University of Rochester, Rochester, New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Heather","family":"Link","sequence":"additional","affiliation":[{"name":"Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, University of Rochester Medical Center, Rochester, New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paola","family":"Torres","sequence":"additional","affiliation":[{"name":"Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, University of Texas, Houston, Texas"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Annie","family":"Kim","sequence":"additional","affiliation":[{"name":"Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, University of Texas, Houston, Texas"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Devon J.","family":"King","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Albany Medical Center, Albany, New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cari","family":"Eckman","sequence":"additional","affiliation":[{"name":"Albany Medical College, Albany, New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anna","family":"Varlamov","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Winnie Palmer Hospital for Women and Babies, Orlando Health, Orlando, Florida"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Scott","family":"Dexter","sequence":"additional","affiliation":[{"name":"Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Albany Medical Center, Albany, New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eva K.","family":"Pressman","sequence":"additional","affiliation":[{"name":"Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, University of Rochester Medical Center, Rochester, New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eleazar","family":"Soto-Torres","sequence":"additional","affiliation":[{"name":"Department of Clinical and Translational Research, University of Rochester, Rochester, New York"},{"name":"Department of Obstetrics and Gynecology, Department of Public Health Sciences, University of Rochester, Rochester, New York"},{"name":"Department of Public Health Sciences, University of Rochester, Rochester, New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amol","family":"Malshe","sequence":"additional","affiliation":[{"name":"Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, University of Rochester Medical Center, Rochester, New York"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2018,12,15]]},"container-title":["American Journal of Perinatology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/s-0038-1675647.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,26]],"date-time":"2019-05-26T18:31:22Z","timestamp":1558895482000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/s-0038-1675647"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,12,15]]},"references-count":0,"journal-issue":{"issue":"07","published-online":{"date-parts":[[2019,5,26]]},"published-print":{"date-parts":[[2019,6]]}},"URL":"https:\/\/doi.org\/10.1055\/s-0038-1675647","relation":{},"ISSN":["0735-1631","1098-8785"],"issn-type":[{"value":"0735-1631","type":"print"},{"value":"1098-8785","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,12,15]]}}}