{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,4]],"date-time":"2026-06-04T02:05:57Z","timestamp":1780538757747,"version":"3.54.1"},"reference-count":35,"publisher":"Federa\u00e7\u00e3o das Associa\u00e7\u00f5es de Ginecologia e Obstetr\u00edcia","issue":"12","license":[{"start":{"date-parts":[[2018,12,7]],"date-time":"2018-12-07T00:00:00Z","timestamp":1544140800000},"content-version":"vor","delay-in-days":6,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rev Bras Ginecol Obstet"],"published-print":{"date-parts":[[2018,12]]},"abstract":"<jats:p>\n            Objective\u2003To describe caffeine consumption during pregnancy and its association with low birth weight (LBW) and preterm birth in the birth cohort of Ribeir\u00e3o Preto, state of S\u00e3o Paulo, Brazil, in 2010.<\/jats:p><jats:p>\n            Methods\u2003Cohort study, with descriptive and analytical approach. Data included 7,607 women and their newborns in Ribeir\u00e3o Preto, state of S\u00e3o Paulo, Brazil. The women answered standardized questionnaires about reproductive health, prenatal care, life habits, sociodemographic conditions, and information about coffee intake. The independent variable was high caffeine consumption (\u2265300 mg\/day) from coffee during pregnancy, and the dependent variables were LBW (birth weight\u2009&lt;\u20092,500 g) and preterm birth (&lt; 37 weeks of gestational age). Four adjusted polytomous logistic regression models, relative risk (RR) and 95% confidence interval (CI) were fitted: biological and sociodemographic conditions; obstetric history; current gestational conditions; and all variables included in the previous models.<\/jats:p><jats:p>\n            Results\u2003A total of 4,908 (64.5%) mothers consumed caffeine, 143 (2.9%) of whom reported high consumption. High caffeine intake was significantly associated with reduced education and with the occupation of the head of the family, nonwhite skin color, not having a partner, higher parity, previous abortion and preterm birth, urinary tract infection, threatened abortion, alcohol consumption and smoking. No association was found between high caffeine consumption and LBW or preterm birth in both unadjusted (RR\u2009=\u20091.45; 95% CI: 0.91\u20132.32; and RR\u2009=\u20091.16; 95% CI: 0.77\u20131.75, respectively) and adjusted analyses (RR\u2009=\u20091.42; 95% CI: 0.85\u20132.38; and RR\u2009=\u20091.03; 95% CI: 0.65\u20131.63, respectively).<\/jats:p><jats:p>\n            Conclusion\u2003In this cohort, high caffeine intake was lower than in other studies and no association with LBW or preterm birth was found.<\/jats:p>","DOI":"10.1055\/s-0038-1675806","type":"journal-article","created":{"date-parts":[[2018,12,7]],"date-time":"2018-12-07T23:45:23Z","timestamp":1544226323000},"page":"749-756","source":"Crossref","is-referenced-by-count":15,"title":["Association between Caffeine Consumption in Pregnancy and Low Birth Weight and Preterm Birth in the birth Cohort of Ribeir\u00e3o Preto"],"prefix":"10.61622","volume":"40","author":[{"given":"Fernanda Pino","family":"Vitti","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Faculdade de Medicina de Ribeir\u00e3o Preto da Universidade de S\u00e3o Paulo, Ribeir\u00e3o Preto, SP, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlos","family":"Grandi","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Facultad de Medicina de la Universidad de Buenos Aires, Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ricardo de Carvalho","family":"Cavalli","sequence":"additional","affiliation":[{"name":"Department of Gynecology and Obstetrics, Faculdade de Medicina de Ribeir\u00e3o Preto da Universidade de S\u00e3o Paulo, Ribeir\u00e3o Preto, SP, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vanda Maria Ferreira","family":"Sim\u00f5es","sequence":"additional","affiliation":[{"name":"Department of Public Health, Universidade Federal do Maranh\u00e3o, S\u00e3o Luiz, MA, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ros\u00e2ngela Fernandes Lucena","family":"Batista","sequence":"additional","affiliation":[{"name":"Department of Public Health, Universidade Federal do Maranh\u00e3o, S\u00e3o Luiz, MA, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Viviane Cunha","family":"Cardoso","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Faculdade de Medicina de Ribeir\u00e3o Preto da Universidade de S\u00e3o Paulo, Ribeir\u00e3o Preto, SP, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"47794","published-online":{"date-parts":[[2018,12,7]]},"reference":[{"issue":"01","key":"ref1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1080\/0265203021000007840","article-title":"Effects of caffeine on human health","volume":"20","author":"P Nawrot","year":"2003","journal-title":"Food Addit 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