{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T14:42:02Z","timestamp":1790088122117,"version":"4.0.1"},"reference-count":79,"publisher":"Federa\u00e7\u00e3o das Associa\u00e7\u00f5es de Ginecologia e Obstetr\u00edcia","issue":"01","license":[{"start":{"date-parts":[[2019,1,15]],"date-time":"2019-01-15T00:00:00Z","timestamp":1547510400000},"content-version":"vor","delay-in-days":14,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rev Bras Ginecol Obstet"],"published-print":{"date-parts":[[2019,1]]},"abstract":"<jats:p>\n            Objective\u2003The aim of the present study was to perform a comprehensive review of the literature to provide a complete and clear picture of isthmocele\u2014a hypoechoic area within the myometrium at the site of the uterine scar of a previous cesarean section\u2014by exploring in depth every aspect of this condition.<\/jats:p><jats:p>\n            Methods\u2003A comprehensive review of the literature was performed to identify the most relevant studies about this topic.<\/jats:p><jats:p>\n            Results\u2003Every aspect of isthmocele has been studied and described: pathophysiology, clinical symptoms, classification, and diagnosis. Its treatment, both medical and surgical, has also been reported according to the actual literature data.<\/jats:p><jats:p>\n            Conclusion\u2003Cesarean section is the most common surgical procedure performed worldwide, and one of the consequences of this technique is isthmocele. A single and systematic classification of isthmocele is needed to improve its diagnosis and management. Further studies should be performed to better understand its pathogenesis.<\/jats:p>","DOI":"10.1055\/s-0038-1676109","type":"journal-article","created":{"date-parts":[[2019,1,18]],"date-time":"2019-01-18T10:35:49Z","timestamp":1547807749000},"page":"044-052","source":"Crossref","is-referenced-by-count":41,"title":["Isthmocele: From Risk Factors to Management"],"prefix":"10.61622","volume":"41","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9485-0126","authenticated-orcid":false,"given":"Piergiorgio","family":"Iannone","sequence":"additional","affiliation":[{"name":"Section of Obstetrics and Gynecology, Department of Morphology, Surgery and Experimental Medicine, Azienda Ospedaliero-Universitaria S. Anna, Universit\u00e0 di Ferrara, Cona, Ferrara, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giulia","family":"Nencini","sequence":"additional","affiliation":[{"name":"Section of Obstetrics and Gynecology, Department of Morphology, Surgery and Experimental Medicine, Azienda Ospedaliero-Universitaria S. Anna, Universit\u00e0 di Ferrara, Cona, Ferrara, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gloria","family":"Bonaccorsi","sequence":"additional","affiliation":[{"name":"Section of Obstetrics and Gynecology, Department of Morphology, Surgery and Experimental Medicine, Azienda Ospedaliero-Universitaria S. Anna, Universit\u00e0 di Ferrara, Cona, Ferrara, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruby","family":"Martinello","sequence":"additional","affiliation":[{"name":"Section of Obstetrics and Gynecology, Department of Morphology, Surgery and Experimental Medicine, Azienda Ospedaliero-Universitaria S. Anna, Universit\u00e0 di Ferrara, Cona, Ferrara, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giovanni","family":"Pontrelli","sequence":"additional","affiliation":[{"name":"Section of Obstetrics and Gynaecology, Policlinico di Abano Terme, Abano Terme, Padova, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marco","family":"Scioscia","sequence":"additional","affiliation":[{"name":"Section of Obstetrics and Gynaecology, Policlinico di Abano Terme, Abano Terme, Padova, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luigi","family":"Nappi","sequence":"additional","affiliation":[{"name":"Department of Medical and Surgical Sciences, Institute of Obstetrics and Gynecology, University of Foggia, Foggia, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pantaleo","family":"Greco","sequence":"additional","affiliation":[{"name":"Section of Obstetrics and Gynecology, Department of Morphology, Surgery and Experimental Medicine, Azienda Ospedaliero-Universitaria S. 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