{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,8]],"date-time":"2025-07-08T07:26:00Z","timestamp":1751959560957,"version":"3.37.3"},"reference-count":15,"publisher":"Federa\u00e7\u00e3o das Associa\u00e7\u00f5es de Ginecologia e Obstetr\u00edcia","issue":"01","license":[{"start":{"date-parts":[[2019,2,4]],"date-time":"2019-02-04T00:00:00Z","timestamp":1549238400000},"content-version":"vor","delay-in-days":34,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rev Bras Ginecol Obstet"],"published-print":{"date-parts":[[2019,1]]},"abstract":"<jats:p>\n            Objective\u2003The gestational complication most associated with perinatal mortality and morbidity is spontaneous preterm birth with gestational age\u2009&lt;\u200937 weeks. Therefore, it is necessary to identify its risk factors and attempt its prevention. The benefits of the pessary in prematurity are under investigation. Our objective was to analyze the use of the pessary in the prevention of preterm births in published studies, and to compare its efficacy with other methods.<\/jats:p><jats:p>\n            Methods\u2003Randomized clinical trials published between 2010 and 2018 were selected from electronic databases. Studies on multiple gestations were excluded.<\/jats:p><jats:p>\n            Results\u2003Two studies were in favor of the pessary as a preventive method, one study was contrary to the method and another two showed no statistically significant difference. The meta-analysis showed no statistical difference with the use of a cervical pessary in the reduction of births\u2009&lt;\u200937 (odds ratio [OR]: 0.63; confidence interval [95% CI]: 0.38\u20131.06) and\u2009&lt;\u200934 weeks (OR: 0.74; 95% CI: 0.35\u20131.57)<\/jats:p><jats:p>\n            Conclusion\u2003The pooled data available to date seems to show a lack of efficacy of the cervical pessary in the prevention of preterm birth, although the heterogeneity of the studies made comparisons more difficult.<\/jats:p>","DOI":"10.1055\/s-0038-1676511","type":"journal-article","created":{"date-parts":[[2019,2,4]],"date-time":"2019-02-04T23:31:17Z","timestamp":1549323077000},"page":"053-058","source":"Crossref","is-referenced-by-count":5,"title":["Use of the Pessary in the Prevention of Preterm Delivery"],"prefix":"10.61622","volume":"41","author":[{"given":"Thayane Delazari","family":"Corr\u00eaa","sequence":"additional","affiliation":[{"name":"Departament of Obstetrics and Gynecology, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ester Gomes","family":"Amorim","sequence":"additional","affiliation":[{"name":"Departament of Obstetrics and Gynecology, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jade Aim\u00e9e Guimar\u00e3es","family":"Tomazelli","sequence":"additional","affiliation":[{"name":"Departament of Obstetrics and Gynecology, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4198-0546","authenticated-orcid":false,"suffix":"J\u00fanior","given":"M\u00e1rio Dias","family":"Corr\u00eaa","sequence":"additional","affiliation":[{"name":"Departament of Obstetrics and Gynecology, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"47794","published-online":{"date-parts":[[2019,2,4]]},"reference":[{"issue":"23","key":"ref1","doi-asserted-by":"crossref","first-page":"2317","DOI":"10.1001\/jama.2017.18956","article-title":"Effect of cervical pessary on spontaneous preterm birth in women with singleton pregnancies and short cervical length: a randomized clinical trial","volume":"318","author":"G Saccone","year":"2017","journal-title":"JAMA"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"1800","DOI":"10.1016\/S0140-6736(12)60030-0","article-title":"Cervical pessary in pregnant women with a short cervix (PECEP): an open-label randomised controlled trial","volume":"379","author":"M Goya","year":"2012","journal-title":"Lancet"},{"issue":"11","key":"ref3","doi-asserted-by":"crossref","first-page":"1044","DOI":"10.1056\/NEJMoa1511014","article-title":"A randomized trial of a cervical pessary to prevent preterm singleton birth","volume":"374","author":"K H Nicolaides","year":"2016","journal-title":"N Engl J Med"},{"issue":"12","key":"ref4","doi-asserted-by":"crossref","first-page":"1673","DOI":"10.1111\/jog.13138","article-title":"Combined treatment with cervical pessary and vaginal progesterone for the prevention of preterm birth: A randomized clinical trial","volume":"42","author":"N Karbasian","year":"2016","journal-title":"J Obstet Gynaecol Res"},{"issue":"04","key":"ref5","doi-asserted-by":"crossref","first-page":"907","DOI":"10.1097\/AOG.0000000000002884","article-title":"Cervical pessary compared with vaginal progesterone for preventing early preterm birth: a randomized controlled trial","volume":"132","author":"S Cruz-Melguizo","year":"2018","journal-title":"Obstet Gynecol"},{"issue":"03","key":"ref6","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1097\/GRF.0000000000000044","article-title":"Cervical cerclage","volume":"57","author":"A Suhag","year":"2014","journal-title":"Clin Obstet Gynecol"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/S0140-6736(59)92242-1","article-title":"Treatment of habitual abortion due to cervical incompetence","volume":"274","author":"R G Cross","year":"1959","journal-title":"Lancet"},{"issue":"05","key":"ref8","first-page":"CD007873","article-title":"Cervical pessary for preventing preterm birth","author":"H Abdel-Aleem","year":"2013","journal-title":"Cochrane Database Syst Rev"},{"issue":"04","key":"ref9","first-page":"283","article-title":"Cerclage pessary for preventing preterm birth in women with a singleton pregnancy and a short cervix at 20 to 24 weeks: a randomized controlled trial","volume":"30","author":"S YA Hui","year":"2013","journal-title":"Am J Perinatol"},{"issue":"05","key":"ref12","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1515\/jpm-2017-0009","article-title":"Safety and efficacy of the cervical pessary combined with vaginal progesterone for the prevention of spontaneous preterm birth","volume":"46","author":"G Daskalakis","year":"2018","journal-title":"J Perinat Med"},{"issue":"08","key":"ref14","doi-asserted-by":"crossref","first-page":"1535","DOI":"10.7863\/ultra.16.08054","article-title":"Cervical pessary for preventing preterm birth in singleton pregnancies with short cervical length: a systematic review and meta-analysis","volume":"36","author":"G Saccone","year":"2017","journal-title":"J Ultrasound Med"},{"issue":"02","key":"ref15","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1002\/uog.12300","article-title":"Vaginal progesterone, cerclage or cervical pessary for preventing preterm birth in asymptomatic singleton pregnant women with a history of preterm birth and a sonographic short cervix","volume":"41","author":"Z Alfirevic","year":"2013","journal-title":"Ultrasound Obstet Gynecol"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"2106","DOI":"10.1016\/S0140-6736(16)00350-0","article-title":"Vaginal progesterone prophylaxis for preterm birth (the OPPTIMUM study): a multicentre, randomised, double-blind trial","volume":"387","author":"J E Norman","year":"2016","journal-title":"Lancet"},{"issue":"01","key":"ref17","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1002\/uog.9017","article-title":"Vaginal progesterone reduces the rate of preterm birth in women with a sonographic short cervix: a multicenter, randomized, double-blind, placebo-controlled trial","volume":"38","author":"S S Hassan","year":"2011","journal-title":"Ultrasound Obstet Gynecol"},{"issue":"02","key":"ref18","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1515\/JPM.2003.017","article-title":"Is treatment with vaginal pessaries an option in patients with a sonographically detected short cervix?","volume":"31","author":"B Arabin","year":"2003","journal-title":"J Perinat Med"}],"container-title":["Revista Brasileira de Ginecologia e Obstetr\u00edcia \/ RBGO Gynecology and 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