{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T08:25:44Z","timestamp":1785572744482,"version":"3.56.0"},"reference-count":16,"publisher":"Federa\u00e7\u00e3o das Associa\u00e7\u00f5es de Ginecologia e Obstetr\u00edcia","issue":"02","license":[{"start":{"date-parts":[[2019,2,20]],"date-time":"2019-02-20T00:00:00Z","timestamp":1550620800000},"content-version":"vor","delay-in-days":19,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rev Bras Ginecol Obstet"],"published-print":{"date-parts":[[2019,2]]},"abstract":"<jats:p>\n            Objective:\u2003The present study assessed epidemiological and obstetrical data from pregnant women with syphilis at the Hospital de Cl\u00ednicas of the Universidade Federal do Tri\u00e2ngulo Mineiro (UFTM, in the Portuguese acronym), describing this disease during pregnancy and its vertical transmission for future healthcare actions.<\/jats:p><jats:p>\n            Methods:\u2003Records from pregnant women who had been admitted to the Obstetrics Department of the Hospital de Cl\u00ednicas of the UFTM and were diagnosed with syphilis between 2007 and 2016 were reviewed. A standardized form was used to collect epidemiological, obstetric data and outcomes of congenital infection. The present research has been authorized by the Ethics Committee of the institution.<\/jats:p><jats:p>\n            Results:\u2003There were 268 women diagnosed with syphilis, with an average age of 23.6 years old. The majority of the patients were from Uberaba. Inadequate prenatal care was observed in 37.9% of the pregnant women. Only 34.2% of the patients completed the treatment according to the guidelines issued by the Ministry of Health of Brazil, and 19.8% of the partners of the patients underwent adequate syphilis treatment; 37 (13.8%) couples (patients and partners) underwent correct treatment. Regarding the obstetric outcomes, 4 (1.5%) patients had a miscarriage and 8 (3.4%) had fetal losses (from the fetal loss group, 7 had no adequate treatment); 61 (25.9%) patients had premature births \u2013 this prematurity has been significantly correlated to inadequate or incomplete treatment in 49 (27.9%) patients, compared with 12 (13.0%) patients with premature births and adequate treatment (p\u2009=\u20090.006). The average live newborn weight was 2,840\u2009g; 25.3% had a birth weight\u2009&lt;\u20092,500\u2009g; 74.2% had congenital syphilis, a data with heavy correlation to inadequate or incomplete prenatal care, prematurity, and low birth weight.<\/jats:p><jats:p>\n            Conclusion:\u2003Public awareness policies on adequate prenatal care, intensification of serological screening, and early treatment of syphilis are needed, considering the rise of cases diagnosed during gestation and its potentially preventable deleterious consequences related to congenital transmission.<\/jats:p>","DOI":"10.1055\/s-0038-1676569","type":"journal-article","created":{"date-parts":[[2019,2,28]],"date-time":"2019-02-28T05:24:55Z","timestamp":1551331495000},"page":"090-096","source":"Crossref","is-referenced-by-count":29,"title":["Syphilis in Pregnancy: The Reality in a Public Hospital"],"prefix":"10.61622","volume":"41","author":[{"given":"Rafael Garcia","family":"Torres","sequence":"additional","affiliation":[{"name":"Department of Fetal Medicine, Universidade Federal do Tri\u00e2ngulo Mineiro, Uberaba, MG, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana Laura Neves","family":"Mendon\u00e7a","sequence":"additional","affiliation":[{"name":"Department of Fetal Medicine, Universidade Federal do Tri\u00e2ngulo Mineiro, Uberaba, MG, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Grazielle Cezarine","family":"Montes","sequence":"additional","affiliation":[{"name":"Department of Fetal Medicine, Universidade Federal do Tri\u00e2ngulo Mineiro, Uberaba, MG, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jacqueline J\u00e1come","family":"Manzan","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Universidade de Uberaba, Uberaba, MG, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jo\u00e3o Ulisses","family":"Ribeiro","sequence":"additional","affiliation":[{"name":"Department of Fetal Medicine, Universidade Federal do Tri\u00e2ngulo Mineiro, Uberaba, MG, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2218-4747","authenticated-orcid":false,"given":"Marina Carvalho","family":"Paschoini","sequence":"additional","affiliation":[{"name":"Department of Fetal Medicine, Universidade Federal do Tri\u00e2ngulo Mineiro, Uberaba, MG, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"47794","published-online":{"date-parts":[[2019,2,20]]},"reference":[{"issue":"02","key":"ref2","doi-asserted-by":"crossref","first-page":"e1001396","DOI":"10.1371\/journal.pmed.1001396","article-title":"Global estimates of syphilis in pregnancy and associated adverse outcomes: analysis of multinational antenatal surveillance data","volume":"10","author":"L Newman","year":"2013","journal-title":"PLoS Med"},{"issue":"44","key":"ref3","doi-asserted-by":"crossref","first-page":"1241","DOI":"10.15585\/mmwr.mm6444a3","article-title":"Increase in incidence of congenital syphilis - United States, 2012-2014","volume":"64","author":"V Bowen","year":"2015","journal-title":"MMWR Morb Mortal Wkly Rep"},{"issue":"01","key":"ref5","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1111\/1471-0528.13950","article-title":"The incidence of congenital syphilis in the United Kingdom: February 2010 to January 2015","volume":"124","author":"I Simms","year":"2017","journal-title":"BJOG"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"430585","DOI":"10.1155\/2012\/430585","article-title":"Syphilis Infection during pregnancy: fetal risks and clinical management","volume":"2012","author":"M De Santis","year":"2012","journal-title":"Infect Dis Obstet Gynecol"},{"issue":"06","key":"ref7","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1093\/bjaceaccp\/mkn042","article-title":"Syphilis in pregnancy","volume":"8","author":"S Oswal","year":"2008","journal-title":"Contin Educ Anaesth Crit Care Pain"},{"issue":"02","key":"ref8","doi-asserted-by":"crossref","first-page":"e56713","DOI":"10.1371\/journal.pone.0056713","article-title":"Early antenatal care: does it make a difference to outcomes of pregnancy associated with syphilis? A systematic review and meta-analysis","volume":"8","author":"S J Hawkes","year":"2013","journal-title":"PLoS One"},{"key":"ref9","volume-title":"Manual T\u00e9cnico para Diagn\u00f3stico da S\u00edfilis","year":"2016"},{"issue":"12","key":"ref11","doi-asserted-by":"crossref","first-page":"1581","DOI":"10.1111\/jdv.12734","article-title":"2014 European guideline on the management of syphilis","volume":"28","author":"M Janier","year":"2014","journal-title":"J Eur Acad Dermatol Venereol"},{"issue":"11","key":"ref12","doi-asserted-by":"crossref","first-page":"729","DOI":"10.1258\/ijsa.2008.008279","article-title":"UK National guidelines on management of syphilis 2008","volume":"19","author":"M Kingston","year":"2008","journal-title":"Int J STD AIDS"},{"issue":"02","key":"ref15","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1002\/(SICI)1097-0223(199702)17:2<119::AID-PD39>3.0.CO;2-T","article-title":"In utero infection with Treponema pallidum in early pregnancy","volume":"17","author":"L Nathan","year":"1997","journal-title":"Prenat Diagn"},{"issue":"04","key":"ref16","doi-asserted-by":"crossref","first-page":"352","DOI":"10.1016\/j.ajog.2016.11.1052","article-title":"Syphilis during pregnancy: a preventable threat to maternal-fetal health","volume":"216","author":"M W Rac","year":"2017","journal-title":"Am J Obstet Gynecol"},{"issue":"04","key":"ref17","doi-asserted-by":"crossref","first-page":"426.e1","DOI":"10.1016\/j.ajog.2014.05.049","article-title":"Progression of ultrasound findings of fetal syphilis after maternal treatment","volume":"211","author":"M W Rac","year":"2014","journal-title":"Am J Obstet Gynecol"},{"issue":"06","key":"ref18","first-page":"947","article-title":"Fetal syphilis: clinical and laboratory characteristics","volume":"97","author":"L M Hollier","year":"2001","journal-title":"Obstet Gynecol"},{"issue":"02","key":"ref19","doi-asserted-by":"crossref","first-page":"97","DOI":"10.7863\/jum.1993.12.2.97","article-title":"Fetal syphilis: correlation of sonographic findings and rabbit infectivity testing of amniotic fluid","volume":"12","author":"L Nathan","year":"1993","journal-title":"J Ultrasound Med"},{"issue":"02","key":"ref20","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1097\/GCO.0000000000000258","article-title":"The continuing threat of syphilis in pregnancy","volume":"28","author":"H R Moline","year":"2016","journal-title":"Curr Opin Obstet Gynecol"},{"issue":"02","key":"ref22","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1007\/s10096-013-1948-z","article-title":"Maternal and paternal factors associated with congenital syphilis in Shenzhen, China: a prospective cohort study","volume":"33","author":"J B Qin","year":"2014","journal-title":"Eur J Clin Microbiol Infect Dis"}],"container-title":["Revista Brasileira de Ginecologia e Obstetr\u00edcia \/ RBGO Gynecology and Obstetrics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journalrbgo.org\/article\/syphilis-in-pregnancy-the-reality-in-a-public-hospital\/","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/s-0038-1676569.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,7,18]],"date-time":"2024-07-18T20:53:23Z","timestamp":1721336003000},"score":1,"resource":{"primary":{"URL":"https:\/\/journalrbgo.org\/article\/syphilis-in-pregnancy-the-reality-in-a-public-hospital\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,2]]},"references-count":16,"journal-issue":{"issue":"02","published-online":{"date-parts":[[2019,2,20]]},"published-print":{"date-parts":[[2019,2]]}},"URL":"https:\/\/doi.org\/10.1055\/s-0038-1676569","archive":["Portico","CLOCKSS"],"relation":{},"ISSN":["0100-7203","1806-9339"],"issn-type":[{"value":"0100-7203","type":"print"},{"value":"1806-9339","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,2]]}}}