{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T22:14:56Z","timestamp":1787004896979,"version":"build-2736575974"},"reference-count":0,"publisher":"Georg Thieme Verlag KG","issue":"01","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Neurol Surg B"],"published-print":{"date-parts":[[2020,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>The presence of calcification is uncommon in pituitary adenomas, and often lends support to other diagnoses including craniopharyngioma. The majority of calcified pituitary adenomas are prolactin-secreting tumors. We report two patients with calcified macroprolactinomas, one that was treated medically with a biochemical response and partial tumor response, and one that was treated successfully via an endoscopic endonasal transsphenoidal approach. Suspected calcified prolactinomas can be initially managed medically as per standard treatment for typical prolactinomas; however, the presence of diffuse calcification may hinder tumor shrinkage. Tumors that are refractory to medical treatment can be safely managed with surgery.<\/jats:p>","DOI":"10.1055\/s-0039-1677678","type":"journal-article","created":{"date-parts":[[2019,2,5]],"date-time":"2019-02-05T18:59:30Z","timestamp":1549393170000},"page":"022-029","source":"Crossref","is-referenced-by-count":7,"title":["Calcified Prolactinoma of the Pituitary Gland: Illustrative Case Reports Highlighting Medical versus Surgical Intervention"],"prefix":"10.1055","volume":"81","author":[{"given":"Sherwin","family":"Tavakol","sequence":"additional","affiliation":[{"name":"Department of Neurological Surgery, University of Southern California Keck School of Medicine, Los Angeles, California, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Asma","family":"Hasan","sequence":"additional","affiliation":[{"name":"Division of Endocrinology and Diabetes, University of Southern California Keck School of Medicine, Los Angeles, California, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michelle A.","family":"Wedemeyer","sequence":"additional","affiliation":[{"name":"Department of Neurological Surgery, University of Southern California Keck School of Medicine, Los Angeles, California, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joshua","family":"Bakhsheshian","sequence":"additional","affiliation":[{"name":"Department of Neurological Surgery, University of Southern California Keck School of Medicine, Los Angeles, California, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chia-Shang J.","family":"Liu","sequence":"additional","affiliation":[{"name":"Division of Neuroradiology, Department of Radiology, University of Southern California Keck School of Medicine, Los Angeles, California, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark S.","family":"Shiroishi","sequence":"additional","affiliation":[{"name":"Division of Neuroradiology, Department of Radiology, University of Southern California Keck School of Medicine, Los Angeles, California, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Mathew","sequence":"additional","affiliation":[{"name":"Department of Pathology, University of Southern California Keck School of Medicine, Los Angeles, California, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John D.","family":"Carmichael","sequence":"additional","affiliation":[{"name":"Division of Endocrinology and Diabetes, University of Southern California Keck School of Medicine, Los Angeles, California, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabriel","family":"Zada","sequence":"additional","affiliation":[{"name":"Department of Neurological Surgery, University of Southern California Keck School of Medicine, Los Angeles, California, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2019,2,5]]},"container-title":["Journal of Neurological Surgery Part B: Skull Base"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/s-0039-1677678.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,2,3]],"date-time":"2020-02-03T18:31:03Z","timestamp":1580754663000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/s-0039-1677678"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,2,5]]},"references-count":0,"journal-issue":{"issue":"01","published-online":{"date-parts":[[2020,2,3]]},"published-print":{"date-parts":[[2020,2]]}},"URL":"https:\/\/doi.org\/10.1055\/s-0039-1677678","relation":{},"ISSN":["2193-6331","2193-634X"],"issn-type":[{"value":"2193-6331","type":"print"},{"value":"2193-634X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,2,5]]}}}