{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T19:50:15Z","timestamp":1792698615390,"version":"4.5.0"},"reference-count":0,"publisher":"Georg Thieme Verlag KG","issue":"07","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Am J Perinatol"],"published-print":{"date-parts":[[2020,6]]},"abstract":"<jats:p>\n            Objective\u2003This study aimed to study the role of oropharyngeal administration of colostrum (OAC) in very-low-birth-weight infants for reducing necrotizing enterocolitis (NEC).<\/jats:p><jats:p>\n            Study Design\u2003In this randomized controlled trial, 117 infants were enrolled, 59 were randomized to OAC group and 58 to routine care group. Infants with birth weight\u2009\u2264\u20091,250\u2009g and\/or gestational age\u2009\u2264\u200930 weeks were enrolled. Infants in OAC group received maternal colostrum (0.2 mL), 0.1 mL on either side, after 24 hours of postnatal life and were given every 2 hour for the next 72 hours irrespective of the enteral feeding status of the neonate. The primary outcome of the study was the incidence of NEC (stage 2 or 3).<\/jats:p><jats:p>\n            Results\u2003Baseline characteristics were comparable between the two groups. There was no significant reduction in the incidence of NEC in OAC group (0 [0%] vs. 3 [7.1%]; p\u2009=\u20090.11). There was significant reduction of 7 days of hospital stay in OAC group (34.2\u2009\u00b1\u20095.7 vs. 41.5\u2009\u00b1\u20096.7 days; p\u2009=\u20090.04).The incidence of early-onset sepsis, late-onset sepsis, blood culture positive sepsis, and ventilator-associated pneumonia were comparable between the two groups.<\/jats:p><jats:p>\n            Conclusion\u2003OAC is safe and reduces the duration of hospital stay.<\/jats:p>","DOI":"10.1055\/s-0039-1688817","type":"journal-article","created":{"date-parts":[[2019,5,14]],"date-time":"2019-05-14T23:00:27Z","timestamp":1557874827000},"page":"716-721","source":"Crossref","is-referenced-by-count":38,"title":["Role of Oropharyngeal Administration of Colostrum in Very Low Birth Weight Infants for Reducing Necrotizing Enterocolitis: A Randomized Controlled Trial"],"prefix":"10.1055","volume":"37","author":[{"given":"Deepak","family":"Sharma","sequence":"additional","affiliation":[{"name":"Department of Neonatology, National Institute of Medical Science, Jaipur, Rajasthan, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amandeep","family":"Kaur","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, National Institute of Medical Science, Jaipur, Rajasthan, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nazanin","family":"Farahbakhsh","sequence":"additional","affiliation":[{"name":"Department of Pediatric Pulmonology, Mofid Children's Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sunil","family":"Agarwal","sequence":"additional","affiliation":[{"name":"Helping Hand Polyclinic, Jaipur, Rajasthan, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2019,5,14]]},"container-title":["American Journal of Perinatology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/s-0039-1688817.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,5,20]],"date-time":"2020-05-20T22:39:07Z","timestamp":1590014347000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/s-0039-1688817"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,5,14]]},"references-count":0,"journal-issue":{"issue":"07","published-online":{"date-parts":[[2020,5,20]]},"published-print":{"date-parts":[[2020,6]]}},"URL":"https:\/\/doi.org\/10.1055\/s-0039-1688817","relation":{},"ISSN":["0735-1631","1098-8785"],"issn-type":[{"value":"0735-1631","type":"print"},{"value":"1098-8785","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,5,14]]}}}