{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,5]],"date-time":"2025-11-05T14:26:49Z","timestamp":1762352809030},"reference-count":0,"publisher":"Georg Thieme Verlag KG","issue":"05","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Vet Comp Orthop Traumatol"],"published-print":{"date-parts":[[2019,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n          Objective\u2003Sheep are used as a large animal model for intervertebral disc research. However, for the ovine ventral surgical approach to the cervical disc, limited descriptions exist. We, therefore, give a detailed in vivo anatomical description of this approach in sheep for the use in intervertebral disc regeneration and degeneration models to increase the reproducibility of such interventions.<\/jats:p><jats:p>\n          Materials and Methods\u2003Eighteen female Swiss white alpine sheep, with an age range of 2 to 4 years, were used. A ventral surgical access was performed to establish defined intervertebral disc punch defect from cervical levels C3\/4 to C5\/6. Cervical levels C2\/3 and C6\/7 were used as negative controls. Intraoperative findings, radiographical controls and postoperative clinical follow-up were documented and collected for this clinical report.<\/jats:p><jats:p>\n          Results\u2003All sheep recovered rapidly from the surgical intervention. Two sheep developed wound seroma, which resorbed spontaneously. Two further sheep showed wound dehiscence within 3 days after surgery, which had to be revised. No clinical wound infections occurred and all sheep healed well and did not show any side effects related to the surgical procedure.<\/jats:p><jats:p>\n          Conclusion\u2003The ventral surgical access to the ovine cervical spine is a safe and reliable procedure. The advantage of the cervical intervertebral disc is the easier surgical access and the increased disc height compared to the sheep lumbar spine. Since the ovine cervical intervertebral disc shows a high grade of similarities (e.g. molecular characteristics) compared to human discs, it is a promising degeneration and regeneration model for disc diseases.<\/jats:p>","DOI":"10.1055\/s-0039-1688988","type":"journal-article","created":{"date-parts":[[2019,6,3]],"date-time":"2019-06-03T18:58:24Z","timestamp":1559588304000},"page":"389-393","source":"Crossref","is-referenced-by-count":5,"title":["Ventral Surgical Approach for an Intervertebral Disc Degeneration and Regeneration Model in Sheep Cervical Spine: Anatomic Technical Description, Strengths and Limitations"],"prefix":"10.1055","volume":"32","author":[{"given":"Moritz C.","family":"Deml","sequence":"additional","affiliation":[{"name":"Department for Orthopaedics and Trauma Surgery, Inselspital Bern, University Bern, Bern, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lorin M.","family":"Benneker","sequence":"additional","affiliation":[{"name":"Department for Orthopaedics and Trauma Surgery, Inselspital Bern, University Bern, Bern, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tanja","family":"Schmid","sequence":"additional","affiliation":[{"name":"AO Research Institute Davos, Davos, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daisuke","family":"Sakai","sequence":"additional","affiliation":[{"name":"Department of Orthopedic Surgery, Surgical Science, Tokai University School of Medicine, Isehara, Kanagawa, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christoph E.","family":"Albers","sequence":"additional","affiliation":[{"name":"Department for Orthopaedics and Trauma Surgery, Inselspital Bern, University Bern, Bern, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sven","family":"Hoppe","sequence":"additional","affiliation":[{"name":"Department for Orthopaedics and Trauma Surgery, Inselspital Bern, University Bern, Bern, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephan","family":"Zeiter","sequence":"additional","affiliation":[{"name":"AO Research Institute Davos, Davos, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2019,6,3]]},"container-title":["Veterinary and Comparative Orthopaedics and Traumatology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/s-0039-1688988.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,9,12]],"date-time":"2019-09-12T06:42:23Z","timestamp":1568270543000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/s-0039-1688988"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,6,3]]},"references-count":0,"journal-issue":{"issue":"05","published-online":{"date-parts":[[2019,9,11]]},"published-print":{"date-parts":[[2019,9]]}},"URL":"https:\/\/doi.org\/10.1055\/s-0039-1688988","relation":{},"ISSN":["0932-0814","2567-6911"],"issn-type":[{"value":"0932-0814","type":"print"},{"value":"2567-6911","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,6,3]]}}}