{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T14:21:09Z","timestamp":1792678869069,"version":"4.5.0"},"reference-count":21,"publisher":"Federa\u00e7\u00e3o das Associa\u00e7\u00f5es de Ginecologia e Obstetr\u00edcia","issue":"06","license":[{"start":{"date-parts":[[2019,6,27]],"date-time":"2019-06-27T00:00:00Z","timestamp":1561593600000},"content-version":"vor","delay-in-days":26,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rev Bras Ginecol Obstet"],"published-print":{"date-parts":[[2019,6]]},"abstract":"<jats:p>Objective\u2003The main objective of the present study was to estimate the annual treatment costs of invasive cervical cancer (ICC) per patient at an oncology center in Brazil from a societal perspective by considering direct medical, direct nonmedical, and indirect costs.<\/jats:p>\n                  <jats:p>Methods\u2003A cost analysis descriptive study, in which direct medical, direct nonmedical, and indirect costs were collected using a microcosting approach, was conducted between May 2014 and July 2016 from a societal perspective. The study population consisted of women diagnosed with ICC admitted to a tertiary hospital in Recife, state of Pernambuco, Brazil. The annual cost per patient was estimated in terms of the value of American Dollars (US$) in 2016.<\/jats:p>\n                  <jats:p>Results\u2003From a societal perspective, the annual ICC treatment cost per patient was US$ 2,219.73. Direct medical costs were responsible for 81.2% of the total value, of which radiotherapy and outpatient chemotherapy had the largest share. Under the base-case assumption, the estimated cost to the national budget of a year of ICC treatment in the Brazilian population was US$ 25,954,195.04.<\/jats:p>\n                  <jats:p>Conclusion\u2003We found a high economic impact of health care systems treating ICC in a poor region of Brazil. These estimates could be applicable to further evaluations of the cost-effectiveness of preventing and treating ICC.<\/jats:p>","DOI":"10.1055\/s-0039-1692412","type":"journal-article","created":{"date-parts":[[2019,6,27]],"date-time":"2019-06-27T19:54:05Z","timestamp":1561665245000},"page":"387-393","source":"Crossref","is-referenced-by-count":14,"title":["Estimation of the Costs of Invasive Cervical Cancer Treatment in Brazil: A Micro-Costing Study"],"prefix":"10.61622","volume":"41","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5215-5085","authenticated-orcid":false,"given":"Candice Lima","family":"Santos","sequence":"additional","affiliation":[{"name":"Department of Oncology, Instituto de Medicina Integral Prof. Fernando Figueira, Recife, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ariani Impieri","family":"Souza","sequence":"additional","affiliation":[{"name":"Medical School, Faculdade Pernambucana de Sa\u00fade, Recife, PE, Brazil"},{"name":"Department of Research, Instituto de Medicina Integral Prof. Fernando Figueira, Recife, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9 Natal","family":"Figueiroa","sequence":"additional","affiliation":[{"name":"Department of Research, Instituto de Medicina Integral Prof. Fernando Figueira, Recife, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suely Arruda","family":"Vidal","sequence":"additional","affiliation":[{"name":"Department of Research, Instituto de Medicina Integral Prof. Fernando Figueira, Recife, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"47794","published-online":{"date-parts":[[2019,6,27]]},"reference":[{"issue":"02","key":"ref2","doi-asserted-by":"crossref","first-page":"87","DOI":"10.3322\/caac.21262","article-title":"Global cancer statistics, 2012","volume":"65","author":"L A Torre","year":"2015","journal-title":"CA Cancer J Clin"},{"key":"ref3","volume-title":"Estimativa 2018: Incid\u00eancia de C\u00e2ncer no Brasil","year":"2017"},{"issue":"03","key":"ref4","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1016\/j.bpobgyn.2006.01.018","article-title":"Cervical cancer in the developing world","volume":"20","author":"L C Zeferino","year":"2006","journal-title":"Best Pract Res Clin Obstet Gynaecol"},{"issue":"04","key":"ref5","doi-asserted-by":"crossref","first-page":"289","DOI":"10.6061\/clinics\/2015(04)12","article-title":"Annual national direct and indirect cost estimates of the prevention and treatment of cervical cancer in Brazil","volume":"70","author":"H MD Novaes","year":"2015","journal-title":"Clinics (S\u00e3o Paulo)"},{"key":"ref7","volume-title":"World Cancer Report 2014","author":"B W Stewart","year":"2014"},{"key":"ref8","volume-title":"Methods for the Economic Evaluation in Health Care Programmes. 4th ed","author":"M F Drummond","year":"2015"},{"issue":"08","key":"ref10","doi-asserted-by":"crossref","first-page":"734","DOI":"10.1056\/NEJMoa1309748","article-title":"Improved survival with bevacizumab in advanced cervical cancer","volume":"370","author":"K S Tewari","year":"2014","journal-title":"N Engl J Med"},{"issue":"03","key":"ref11","doi-asserted-by":"crossref","first-page":"490","DOI":"10.1016\/j.ygyno.2015.02.027","article-title":"A Markov model to evaluate cost-effectiveness of antiangiogenesis therapy using bevacizumab in advanced cervical cancer","volume":"137","author":"L E Minion","year":"2015","journal-title":"Gynecol Oncol"},{"issue":"01","key":"ref12","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/j.ygyno.2014.11.003","article-title":"Bevacizumab in recurrent, persistent, or advanced stage carcinoma of the cervix: is it cost-effective?","volume":"136","author":"N T Phippen","year":"2015","journal-title":"Gynecol Oncol"},{"key":"ref14","volume-title":"Indicadores Sociais Municipais: Uma An\u00e1lise dos Resultados do Universo do Censo Demogr\u00e1fico 2010","year":"2011"},{"key":"ref16","volume-title":"Diretrizes Metodol\u00f3gicas: Diretrizes de Avalia\u00e7\u00e3o Econ\u00f4mica. 2a ed","year":"2014"},{"issue":"08","key":"ref17","doi-asserted-by":"crossref","first-page":"889","DOI":"10.1111\/j.1471-0528.1989.tb03341.x","article-title":"Revised FIGO staging for gynaecological cancer","volume":"96","author":"J H Shepherd","year":"1989","journal-title":"Br J Obstet Gynaecol"},{"issue":"06","key":"ref18","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1097\/00000421-198212000-00014","article-title":"Toxicity and response criteria of the Eastern Cooperative Oncology Group","volume":"5","author":"M M Oken","year":"1982","journal-title":"Am J Clin Oncol"},{"key":"ref25","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1590\/S0103-40142013000200003","article-title":"25 anos do Sistema \u00danico de Sa\u00fade: resultados e desafios","volume":"27","author":"E V Mendes","year":"2013","journal-title":"Estud Av"},{"issue":"40","key":"ref26","doi-asserted-by":"crossref","first-page":"5519","DOI":"10.1016\/j.vaccine.2009.06.097","article-title":"Cost-effectiveness analysis of a cervical cancer vaccine in five Latin American countries","volume":"27","author":"L Colantonio","year":"2009","journal-title":"Vaccine"},{"issue":"32","key":"ref27","doi-asserted-by":"crossref","first-page":"4866","DOI":"10.1016\/j.vaccine.2012.04.087","article-title":"Economic modelling assessment of the HPV quadrivalent vaccine in Brazil: a dynamic individual-based approach","volume":"30","author":"T Vanni","year":"2012","journal-title":"Vaccine"},{"key":"ref28","doi-asserted-by":"crossref","first-page":"117","DOI":"10.4236\/ojog.2019.92012","article-title":"Techniques for determining the treatment costs of cervical cancer: a systematic review","volume":"9","author":"C AAL Santos","year":"2019","journal-title":"Open J Obstet Gynecol"},{"key":"ref29","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1590\/S1413-80502013000400005","article-title":"Desigualdade socioecon\u00f4mica no acesso aos servi\u00e7os de sa\u00fade no Brasil: um estudo comparativo entre as regi\u00f5es brasileiras em 1998 e 2008","volume":"17","author":"M V Andrade","year":"2013","journal-title":"Econ Apl"},{"key":"ref30","doi-asserted-by":"crossref","first-page":"35","DOI":"10.32635\/2176-9745.RBC.2016v62n1.177","volume":"62","author":"L P Ara\u00fajo","year":"2016","journal-title":"Rev Bras Cancerol"},{"issue":"05","key":"ref33","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1016\/S1470-2045(13)70048-2","article-title":"Planning cancer control in Latin America and the Caribbean","volume":"14","author":"P E Goss","year":"2013","journal-title":"Lancet Oncol"},{"issue":"04","key":"ref34","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1111\/j.1524-4733.2008.00489.x","article-title":"Transferability of economic evaluations across jurisdictions: ISPOR Good Research Practices Task Force report","volume":"12","author":"M Drummond","year":"2009","journal-title":"Value Health"}],"container-title":["Revista Brasileira de Ginecologia e Obstetr\u00edcia \/ RBGO Gynecology and Obstetrics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journalrbgo.org\/article\/estimation-of-the-costs-of-invasive-cervical-cancer-treatment-in-brazil-a-micro-costing-study\/","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/s-0039-1692412.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,7,18]],"date-time":"2024-07-18T16:56:46Z","timestamp":1721321806000},"score":1,"resource":{"primary":{"URL":"https:\/\/journalrbgo.org\/article\/estimation-of-the-costs-of-invasive-cervical-cancer-treatment-in-brazil-a-micro-costing-study\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,6]]},"references-count":21,"journal-issue":{"issue":"06","published-online":{"date-parts":[[2019,6,27]]},"published-print":{"date-parts":[[2019,6]]}},"URL":"https:\/\/doi.org\/10.1055\/s-0039-1692412","archive":["Portico","CLOCKSS"],"relation":{},"ISSN":["0100-7203","1806-9339"],"issn-type":[{"value":"0100-7203","type":"print"},{"value":"1806-9339","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,6]]}}}