{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,8]],"date-time":"2026-05-08T09:39:08Z","timestamp":1778233148279,"version":"3.51.4"},"reference-count":0,"publisher":"Georg Thieme Verlag KG","issue":"04","license":[{"start":{"date-parts":[[2019,12,5]],"date-time":"2019-12-05T00:00:00Z","timestamp":1575504000000},"content-version":"vor","delay-in-days":187,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Aorta"],"published-print":{"date-parts":[[2019,6]]},"abstract":"<jats:p>\n            Background\u2003Abdominal aortic aneurysm has become increasingly important owing to demographic changes. Some other diseases, for example, cholecystolithiasis, chronic obstructive pulmonary disease, and hernias, seem to co-occur with abdominal aortic aneurysm. The aim of this retrospective analysis was to identify new comorbidities associated with abdominal aortic aneurysm.<\/jats:p><jats:p>\n            Methods\u2003We compared 100 patients with abdominal aortic aneurysms and 100 control patients. Their preoperative computed tomographic scans were examined by two investigators independently, for the presence of hernias, diverticulosis, and cholecystolithiasis. Medical records were also reviewed. Statistical analysis was performed using univariate analysis and multiple logistic regression analysis.<\/jats:p><jats:p>\n            Results\u2003The aneurysm group had a higher frequency of diverticulosis (p\u2009=\u20090.008). There was no significant difference in the occurrence of hernia (p\u2009=\u20090.073) or cholecystolithiasis (p\u2009=\u20091.00). Aneurysm patients had a significantly higher American Society of Anesthesiology score (2.84 vs. 2.63; p\u2009=\u20090.015) and were more likely to have coronary artery disease (p\u2009&lt;\u20090.001), congestive heart failure (p\u2009&lt;\u20090.001), or chronic obstructive pulmonary disease (p\u2009&lt;\u20090.001). Aneurysm patients were more likely to be former (p\u2009=\u20090.034) or current (p\u2009=\u20090.006) smokers and had a significantly higher number of pack years (p\u2009&lt;\u20090.001). Aneurysm patients also had a significantly poorer lung function. In multivariate analysis, the following factors were associated with aneurysms: chronic obstructive pulmonary disease (odds ratio, OR\u2009=\u200912.24; p\u2009=\u20090.002), current smoking (OR\u2009=\u20094.14; p\u2009=\u20090.002), and coronary artery disease (OR\u2009=\u20092.60; p\u2009=\u20090.020).<\/jats:p><jats:p>\n            Conclusions\u2003Our comprehensive analysis identified several comorbidities associated with abdominal aortic aneurysms. These results could help to recognize aneurysms earlier by targeting individuals with these comorbidities for screening.<\/jats:p>","DOI":"10.1055\/s-0039-1692456","type":"journal-article","created":{"date-parts":[[2019,12,5]],"date-time":"2019-12-05T19:10:20Z","timestamp":1575573020000},"page":"108-114","source":"Crossref","is-referenced-by-count":15,"title":["Comorbidities Associated with Large Abdominal Aortic Aneurysms"],"prefix":"10.1055","volume":"07","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0967-6723","authenticated-orcid":false,"given":"Verena","family":"M\u00fcller","sequence":"additional","affiliation":[{"name":"Surgical Clinic, Campus Charit\u00e9 Mitte and Campus Virchow-Klinikum, Charit\u00e9 \u2013 Universit\u00e4tsmedizin Berlin, corporate member of Freie Universit\u00e4t Berlin, Humboldt-Universit\u00e4t zu Berlin, and Berlin Institute of Health, Berlin, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Milena","family":"Miszczuk","sequence":"additional","affiliation":[{"name":"Vascular Surgery Clinic, Charit\u00e9 \u2013 Universit\u00e4tsmedizin Berlin, corporate member of Freie Universit\u00e4t Berlin, Humboldt-Universit\u00e4t zu Berlin, and Berlin Institute of Health, Berlin, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christian E.","family":"Althoff","sequence":"additional","affiliation":[{"name":"Institute of Radiology, Campus Charit\u00e9 Mitte, Charit\u00e9 \u2013 Universit\u00e4tsmedizin Berlin, corporate member of Freie Universit\u00e4t Berlin, Humboldt-Universit\u00e4t zu Berlin, and Berlin Institute of Health, Berlin, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1977-1908","authenticated-orcid":false,"given":"Andrea","family":"Stroux","sequence":"additional","affiliation":[{"name":"Institute of Medical Biometrics and Clinical Epidemiology, Charit\u00e9 \u2013 Universit\u00e4tsmedizin Berlin, corporate member of Freie Universit\u00e4t Berlin, Humboldt-Universit\u00e4t zu Berlin, and Berlin Institute of Health, Berlin, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andreas","family":"Greiner","sequence":"additional","affiliation":[{"name":"Vascular Surgery Clinic, Charit\u00e9 \u2013 Universit\u00e4tsmedizin Berlin, corporate member of Freie Universit\u00e4t Berlin, Humboldt-Universit\u00e4t zu Berlin, and Berlin Institute of Health, Berlin, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5753-8766","authenticated-orcid":false,"given":"Helena","family":"Kuivaniemi","sequence":"additional","affiliation":[{"name":"Division of Molecular Biology and Human Genetics, Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Stellenbosch University, Tygerberg, South Africa"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6725-525X","authenticated-orcid":false,"given":"Irene","family":"Hinterseher","sequence":"additional","affiliation":[{"name":"Vascular Surgery Clinic, Charit\u00e9 \u2013 Universit\u00e4tsmedizin Berlin, corporate member of Freie Universit\u00e4t Berlin, Humboldt-Universit\u00e4t zu Berlin, and Berlin Institute of Health, Berlin, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2019,12,5]]},"container-title":["AORTA"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/s-0039-1692456.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,12,18]],"date-time":"2019-12-18T12:54:23Z","timestamp":1576673663000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/s-0039-1692456"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,6]]},"references-count":0,"journal-issue":{"issue":"04","published-online":{"date-parts":[[2019,12,16]]},"published-print":{"date-parts":[[2019,6]]}},"URL":"https:\/\/doi.org\/10.1055\/s-0039-1692456","relation":{},"ISSN":["2325-4637"],"issn-type":[{"value":"2325-4637","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,6]]}}}