{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,20]],"date-time":"2026-02-20T18:42:48Z","timestamp":1771612968543,"version":"3.50.1"},"reference-count":44,"publisher":"Georg Thieme Verlag KG","issue":"05","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Neurol Surg B Skull Base"],"published-print":{"date-parts":[[2020,10]]},"abstract":"<jats:p>\n            Introduction\u2003In pediatric patients, endoscopic transnasal surgery (ETNS) poses challenges because of the small size of the developing skull and narrow endonasal corridors.<\/jats:p><jats:p>\n            Objective\u2003This study aimed to evaluate the efficacy of ETNS in children by assessing our experience of endoscopic skull base surgery.<\/jats:p><jats:p>\n            Materials and Methods\u2003All pediatric patients (n\u2009=\u200954) who were eligible for surgery using only the endonasal endoscopic approach at our tertiary center between 2012 and 2018 were included in this study. The surgeries were performed simultaneously by an endoscopic skull base team of neurosurgeons and otolaryngologists. Hormonal analyses were conducted before and after surgery in all patients with sellar\/parasellar lesions. Patients older than 8 years underwent smell and visual testing.<\/jats:p><jats:p>\n            Results\u2003In the 54 patients aged 1 to 17 years who underwent surgery, craniopharyngioma was the most common pathology (29.6%), followed by pituitary adenoma (22.2%). Gross total resection was achieved in 33 (76.7%) of 41 patients who underwent surgery because of the presence of tumors. All visual deficits improved, although one patient sustained olfactory deterioration. Sixteen (29.6%) patients presented with complications such as transient diabetes insipidus and temporary visual loss.<\/jats:p><jats:p>\n            Conclusions\u2003Despite anatomy-related challenges in children, adequate results can be achieved with high rates of success, and the functional and anatomical integrity of the developing skull and nose of children can be preserved. In pediatric patients, ETNS is a safe and effective option for addressing various lesions along the skull base.<\/jats:p>","DOI":"10.1055\/s-0039-1692641","type":"journal-article","created":{"date-parts":[[2019,6,18]],"date-time":"2019-06-18T22:51:47Z","timestamp":1560898307000},"page":"515-525","source":"Crossref","is-referenced-by-count":12,"title":["Endoscopic Transnasal Skull Base Surgery in Pediatric Patients"],"prefix":"10.1055","volume":"81","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8137-0510","authenticated-orcid":false,"given":"Gokmen","family":"Kahilogullari","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Ankara University, Ankara, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cem","family":"Meco","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology, Ankara University, Turkey"},{"name":"Department of Otolaryngology, Salzburg Paracelsus Medical University, Salzburg, Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Suha","family":"Beton","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology, Ankara University, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Murat","family":"Zaimoglu","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Ankara University, Ankara, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Onur","family":"Ozgural","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Ankara University, Ankara, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hazan","family":"Basak","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology, Ankara University, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Melih","family":"Bozkurt","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Ankara University, Ankara, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Agahan","family":"Unlu","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Ankara University, Ankara, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2019,6,18]]},"reference":[{"issue":"01","key":"ref1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1055\/s-0038-1624584","article-title":"Recent advances in pediatric skull base surgery","volume":"79","author":"D M Fliss","year":"2018","journal-title":"J Neurol Surg B Skull Base"},{"issue":"03","key":"ref2","doi-asserted-by":"crossref","first-page":"227","DOI":"10.3171\/2012.10.PEDS12160","article-title":"Endoscopic endonasal skull base surgery in the pediatric population","volume":"11","author":"S Chivukula","year":"2013","journal-title":"J Neurosurg Pediatr"},{"key":"ref3","first-page":"75","article-title":"Fully endoscopic expanded endonasal approach treating skull base lesions in pediatric patients","volume":"106","author":"A Kassam","year":"2007","journal-title":"J Neurosurg"},{"issue":"01","key":"ref4","first-page":"65","article-title":"The expanded endonasal approach for the treatment of intracranial skull base disease in the pediatric population","volume":"23","author":"S Khalili","year":"2015","journal-title":"Curr Opin Otolaryngol Head Neck Surg"},{"issue":"11","key":"ref5","doi-asserted-by":"crossref","first-page":"1298","DOI":"10.1016\/j.ijporl.2010.08.009","article-title":"Endoscopic endonasal transsphenoidal surgery for sellar tumors in children","volume":"74","author":"D Locatelli","year":"2010","journal-title":"Int J Pediatr Otorhinolaryngol"},{"issue":"06","key":"ref6","doi-asserted-by":"crossref","first-page":"1818","DOI":"10.1097\/SCS.0000000000001946","article-title":"Endonasal endoscopic transsphenoidal approach to lesions of the sellar region in pediatric patients","volume":"26","author":"R Zhan","year":"2015","journal-title":"J Craniofac Surg"},{"issue":"12","key":"ref7","doi-asserted-by":"crossref","first-page":"2017","DOI":"10.1016\/j.jcms.2018.09.013","article-title":"Endoscopic endonasal skull base surgery in pediatric patients. 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