{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T12:14:38Z","timestamp":1788437678518,"version":"build-2803163510"},"reference-count":0,"publisher":"Georg Thieme Verlag KG","issue":"14","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Am J Perinatol"],"published-print":{"date-parts":[[2019,12]]},"abstract":"<jats:p>\n            Objective\u2003To estimate the incidence of and define risk factors for postpartum infectious complications after vaginal birth after cesarean (VBAC) complicated by chorioamnionitis.<\/jats:p><jats:p>\n            Study Design\u2003A secondary analysis of the Eunice Kennedy Shriver National Institute of Child Health and Human Development Maternal-Fetal Medicine Unit Cesarean Registry was performed. The primary outcome was a composite of postpartum infection: endometritis, sepsis, pelvic abscess, urinary tract infection, necrotizing fasciitis, and septic pelvic thrombophlebitis. Peripartum predictors were compared using parametric and nonparametric tests, as appropriate, and multivariate predictors assessed using logistic regression.<\/jats:p><jats:p>\n            Results\u2003A total of 559 subjects had chorioamnionitis in labor and a successful VBAC. Twenty-four (4.3%) subjects experienced the primary outcome, mainly due to endometritis (19\/24). Significant factors included preterm delivery &lt;32 weeks (odds ratio [OR]: 3.05, 95% confidence interval [CI]: 1.32\u20137.06) and body mass index (BMI) \u226540 (OR: 4.63, 95% CI: 1.25\u201317.14). Receipt of postpartum antibiotics was protective against postpartum infection (OR: 0.28, 95% CI: 0.12\u20130.65). In multivariate analysis, preterm delivery &lt;32 weeks, BMI \u226540, and receipt of postpartum antibiotics remained associated with postpartum infection.<\/jats:p><jats:p>\n            Conclusion\u2003Nearly 5% of women with chorioamnionitis had a postpartum infectious complication after vaginal delivery, with higher rates in those delivering at &lt;32 weeks and with prepregnancy BMI \u226540. Receipt of postpartum antibiotics decreased the odds of postpartum infection markedly.<\/jats:p>","DOI":"10.1055\/s-0039-1692718","type":"journal-article","created":{"date-parts":[[2019,7,26]],"date-time":"2019-07-26T18:55:21Z","timestamp":1564167321000},"page":"1437-1441","source":"Crossref","is-referenced-by-count":15,"title":["Chorioamnionitis and Infectious Complications after Vaginal Delivery"],"prefix":"10.1055","volume":"36","author":[{"given":"Anna E.","family":"DeNoble","sequence":"additional","affiliation":[{"name":"Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Duke University Medical Center, Durham, North Carolina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R. Phillips","family":"Heine","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Wake Forest Baptist Health, Winston-Salem, North Carolina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah K.","family":"Dotters-Katz","sequence":"additional","affiliation":[{"name":"Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Duke University Medical Center, Durham, North Carolina"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2019,6,25]]},"container-title":["American Journal of Perinatology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/s-0039-1692718.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,12,13]],"date-time":"2019-12-13T15:41:35Z","timestamp":1576251695000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/s-0039-1692718"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,6,25]]},"references-count":0,"journal-issue":{"issue":"14","published-online":{"date-parts":[[2019,11,28]]},"published-print":{"date-parts":[[2019,12]]}},"URL":"https:\/\/doi.org\/10.1055\/s-0039-1692718","relation":{},"ISSN":["0735-1631","1098-8785"],"issn-type":[{"value":"0735-1631","type":"print"},{"value":"1098-8785","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,6,25]]}}}