{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T16:35:58Z","timestamp":1762014958589,"version":"build-2065373602"},"reference-count":35,"publisher":"Georg Thieme Verlag KG","issue":"02","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Neurol Surg B Skull Base"],"published-print":{"date-parts":[[2021,4]]},"abstract":"<jats:p>\n            Objective\u2003A novel technique is described for transpalatal hypophysectomy as an option for sellar region surgery using a microscope and\/or endoscope.<\/jats:p><jats:p>\n            Technique\u2003A straight submucosal tunnel (approximately 20\u2009mm in diameter; 40\u201350\u2009mm long\u2014half the length required by conventional transsphenoidal hypophysectomy) is dissected in favorable alignment with the main tumor axis, providing a direct view that allows the surgeon to operate on large suprasellar tumors, even in cases of extra-axial expansion.<\/jats:p><jats:p>\n            Results\u2003In a 25-year period, over 50 patients benefited from this surgery. Macroadenomas devoid of extra-axial expansions were totally excised (76.5%), otherwise, partially (23.5%). Forty-nine patients (98%) were extubated soon after surgery. Mean surgery duration was 3 hour 32 minute, with 2 days 6 hour before free feeding was restored. Postoperative hospitalization under neurosurgical care averaged 6 days 6 hour. Currently, patients undergoing the procedure do not require nasal tampons and can eat soft foods soon after recovery from anesthesia. Although two patients (3.9%) presented with oronasal fistulae postoperatively, no episodes of severe hemorrhage occurred during surgery and there were no cases of liquoric fistulae, visual impairment, panhypopituitarism, or severe syndrome of inappropriate antidiuretic hormone secretion.<\/jats:p><jats:p>\n            Conclusion\u2003The new surgical approach is safe, effective, and well accepted by patients, who reported low levels of discomfort. Postsurgical complications or sequela are currently rare, but further operations should be performed using more appropriate materials, instruments, and equipment to allow comparisons with other techniques.<\/jats:p>","DOI":"10.1055\/s-0039-1694051","type":"journal-article","created":{"date-parts":[[2019,9,18]],"date-time":"2019-09-18T22:48:10Z","timestamp":1568846890000},"page":"216-232","source":"Crossref","is-referenced-by-count":0,"title":["A Novel Technique for Transpalatal Hypophysectomy"],"prefix":"10.1055","volume":"82","author":[{"given":"Ilton Guenhiti","family":"Shinzato","sequence":"additional","affiliation":[{"name":"Hospital Santa Casa de Campo Grande, Universidade Federal de Mato Grosso do Sul, Campo Grande, Brazil"},{"name":"COPPE, Universidade Federal do Rio de Janeiro, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Felipe Bouchabki","family":"de Almeida Guardini","sequence":"additional","affiliation":[{"name":"Hospital Santa Casa de Campo Grande, Universidade Federal de Mato Grosso do Sul, Campo Grande, Brazil"},{"name":"Brazilian Neurosurgery Society, S\u00e3o Paulo, Brazil"},{"name":"Universidade Federal de S\u00e3o Paulo, Sao Paula, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Herbert","family":"de Abreu Cavalcanti","sequence":"additional","affiliation":[{"name":"Hospital Santa Casa de Campo Grande, Universidade Federal de Mato Grosso do Sul, Campo Grande, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tiago Fernando","family":"Scopel","sequence":"additional","affiliation":[{"name":"Hospital Santa Casa de Campo Grande, Universidade Federal de Mato Grosso do Sul, Campo Grande, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fernando","family":"Kobayashi","sequence":"additional","affiliation":[{"name":"Hospital Santa Casa de Campo Grande, Universidade Federal de Mato Grosso do Sul, Campo Grande, Brazil"},{"name":"Brazilian Neurosurgery Society, S\u00e3o Paulo, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anselmo","family":"Costa","sequence":"additional","affiliation":[{"name":"Hospital Santa Casa de Campo Grande, Universidade Federal de Mato Grosso do Sul, Campo Grande, Brazil"},{"name":"Brazilian Neurosurgery Society, S\u00e3o Paulo, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Igor Issao","family":"Moreira Yamamura","sequence":"additional","affiliation":[{"name":"Hospital Santa Casa de Campo Grande, Universidade Federal de Mato Grosso do Sul, Campo Grande, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eurico Ribeiro","family":"Feltrin","sequence":"additional","affiliation":[{"name":"Hospital Santa Casa de Campo Grande, Universidade Federal de Mato Grosso do Sul, Campo Grande, Brazil"},{"name":"Brazilian Neurosurgery Society, S\u00e3o Paulo, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bruno Martins Ferreira","family":"de Andrade","sequence":"additional","affiliation":[{"name":"Hospital Santa Casa de Campo Grande, Universidade Federal de Mato Grosso do Sul, Campo Grande, Brazil"},{"name":"Brazilian Neurosurgery Society, S\u00e3o Paulo, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Franklin Marques","family":"Ennes","sequence":"additional","affiliation":[{"name":"Hospital Santa Casa de Campo Grande, Universidade Federal de Mato Grosso do Sul, Campo Grande, Brazil"},{"name":"Brazilian Neurosurgery Society, S\u00e3o Paulo, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anderson Alves","family":"Silva","sequence":"additional","affiliation":[{"name":"Hospital Santa Casa de Campo Grande, Universidade Federal de Mato Grosso do Sul, Campo Grande, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tiago Andrade","family":"de Oliveira e Silva","sequence":"additional","affiliation":[{"name":"Hospital Santa Casa de Campo Grande, Universidade Federal de Mato Grosso do Sul, Campo Grande, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonio Martins","family":"de Freitas Junior","sequence":"additional","affiliation":[{"name":"Hospital Santa Casa de Campo Grande, Universidade Federal de Mato Grosso do Sul, Campo Grande, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adalberto Santiago","family":"de Souza Junior","sequence":"additional","affiliation":[{"name":"Hospital Santa Casa de Campo Grande, Universidade Federal de Mato Grosso do Sul, Campo Grande, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Danilo Horta","family":"Marcato","sequence":"additional","affiliation":[{"name":"Hospital Santa Casa de Campo Grande, Universidade Federal de Mato Grosso do Sul, Campo Grande, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lucas Rasi","family":"Cunha","sequence":"additional","affiliation":[{"name":"Statistician, Faculdade Senai, Campo Grande, MS, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Neide Trindade","family":"Mendes","sequence":"additional","affiliation":[{"name":"Universidade Federal de S\u00e3o Carlos, S\u00e3o Carlos, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kleber Soline Monteiro","family":"Vargas","sequence":"additional","affiliation":[{"name":"Hospital Santa Casa de Campo Grande, Universidade Federal de Mato Grosso do Sul, Campo Grande, Brazil"},{"name":"Brazilian Neurosurgery Society, S\u00e3o Paulo, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2019,9,18]]},"reference":[{"key":"ref1","first-page":"273","volume-title":"Surgery of space-occupying lesions of the middle skull base","author":"M Samii","year":"1989"},{"key":"ref2","first-page":"1040","article-title":"Zur totalestirpation der hypophysis cerebri","volume":"37","year":"1909","journal-title":"Berl 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