{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,13]],"date-time":"2026-07-13T14:10:11Z","timestamp":1783951811207,"version":"3.55.0"},"reference-count":0,"publisher":"Georg Thieme Verlag KG","issue":"01","funder":[{"name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development","award":["K08HD082287"],"award-info":[{"award-number":["K08HD082287"]}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Am J Perinatol"],"published-print":{"date-parts":[[2020,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n          Objective\u2003To characterize risk and temporal trends for preeclampsia and related outcomes by maternal age.<\/jats:p><jats:p>\n          Study Design\u2003Deliveries to women aged 15 to 54\u2009years in the 1998 to 2014 National Inpatient Sample who had a diagnosis of preeclampsia, eclampsia, or both were included in the analysis. Age was categorized as 15 to 17, 18 to 24, 25 to 29, 30 to 34, 35 to 39, 40 to 44, and 45 to 54\u2009years. The primary outcome was temporal trends in preeclampsia based on maternal age. Secondary outcomes analyzed included risk for severe maternal morbidity.<\/jats:p><jats:p>\n          Results\u2003The proportion of women with preeclampsia aged 15 to 24\u2009years decreased from 42.3% in 1998 to 30.1% in 2014, while preeclampsia among those 30 to 54\u2009years increased from 32.9 to 43.7%. Preeclampsia risk increased for all groups over the study period. Risk for severe morbidity by age group with and without transfusion was \u201cU-shaped,\u201d with risk highest for women 18 to 24 and 40 to 54\u2009years. The risk for abruption, acute renal failure, acute heart failure or pulmonary edema, and stroke was lowest for women aged 15 to 24\u2009years and increased in a \u201cdose-dependent\u201d manner with increasing maternal age. In contrast, eclampsia risk was highest for women aged 15 to 17\u2009years.<\/jats:p><jats:p>\n          Conclusion\u2003With a changing demographic profile of preeclampsia, older women accounted for an increasing proportion of preeclampsia and related adverse outcomes.<\/jats:p>","DOI":"10.1055\/s-0039-1694794","type":"journal-article","created":{"date-parts":[[2019,8,20]],"date-time":"2019-08-20T23:46:33Z","timestamp":1566344793000},"page":"044-052","source":"Crossref","is-referenced-by-count":37,"title":["Maternal Age and Preeclampsia Outcomes during Delivery Hospitalizations"],"prefix":"10.1055","volume":"37","author":[{"given":"Jean-Ju","family":"Sheen","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Columbia University, New York, New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yongmei","family":"Huang","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Columbia University, New York, New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria","family":"Andrikopoulou","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Columbia University, New York, New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jason D.","family":"Wright","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Columbia University, New York, New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dena","family":"Goffman","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Columbia University, New York, New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mary E.","family":"D'Alton","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Columbia University, New York, New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander M.","family":"Friedman","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Columbia University, New York, New York"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2019,8,20]]},"container-title":["American Journal of Perinatology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/s-0039-1694794.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,5,21]],"date-time":"2020-05-21T21:02:21Z","timestamp":1590094941000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/s-0039-1694794"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,8,20]]},"references-count":0,"journal-issue":{"issue":"01","published-online":{"date-parts":[[2020,1,6]]},"published-print":{"date-parts":[[2020,1]]}},"URL":"https:\/\/doi.org\/10.1055\/s-0039-1694794","relation":{},"ISSN":["0735-1631","1098-8785"],"issn-type":[{"value":"0735-1631","type":"print"},{"value":"1098-8785","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,8,20]]}}}