{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,3]],"date-time":"2025-11-03T13:40:10Z","timestamp":1762177210710,"version":"3.37.3"},"reference-count":37,"publisher":"Georg Thieme Verlag KG","issue":"07","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Thorac Cardiovasc Surg"],"published-print":{"date-parts":[[2020,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n          Background\u2003Surgical aortic valve replacement (SAVR) is nowadays discussed whether it remains the gold standard of treatment. In the last decade, there has been a tremendous increase in transcatheter aortic valve implantation (TAVI) due to the growing expertise and excellent results of the catheter-based approach. We, therefore, retrospectively compared the rapid deployment valve (RDV), the Edwards Intuity valve (IEV), with the Edwards Sapien 3 (S3V) with regard to post-procedural hemodynamics.<\/jats:p><jats:p>\n          Methods\u2003A total of 246 patients treated with TAVI or SAVR between February 2009 and November 2015 were included. One-hundred twenty-five patients were analyzed in the SAVR group and compared with 121 patients undergoing TAVI. Transvalvular pressure gradients (PGs) and the incidence and extent of aortic regurgitation (AR) were compared post-procedurally by echocardiography for each valve size. In vitro hemodynamics were analyzed by placing both valves into an aortic silicone phantom connected to a pulsatile flow pump and measured using phase-contrast magnetic resonance imaging (4D flow MRI).<\/jats:p><jats:p>\n          Results\u2003Post-procedurally, mean transvalvular PGs for the 23\u2009mm valves were 9 (7;11.5) versus 13 (9;18) (p\u2009&lt;\u20090.001), whereas maximum PGs were 16.5 (14;22) versus 25.5\u2009mm Hg (17.5;34) (p\u2009&lt;\u20090.001) in IEV and S3V patients, respectively. The 21\u2009mm IEV showed significantly lower transvalvular PGs compared with the 23\u2009mm S3V: mean PGs: 11 (8;13) versus 13 (9;18) (p\u2009&lt;\u20090.05); maximum PG: 19.5 (13;24) versus 25.5 (18;34) mm Hg (p\u2009&lt;\u20090.05). Analysis revealed significantly lower post-procedural transvalvular PGs for larger valves sizes. With respect to AR, the incidence of AR was significantly lower in IEV group (p\u2009&lt;\u20090.05). In vitro velocities and turbulent kinetic energy values showed similar results between both valves.<\/jats:p><jats:p>\n          Conclusion\u2003Implanted RDVs presented a lower incidence of paravalvular regurgitation and were associated with significantly lower post-procedural transvalvular PGs, especially for small valve sizes. Our data might support the application of rapid deployment aortic valves in patients with small aortic annulus in the TAVI era.<\/jats:p>","DOI":"10.1055\/s-0039-1695779","type":"journal-article","created":{"date-parts":[[2019,9,10]],"date-time":"2019-09-10T23:00:17Z","timestamp":1568156417000},"page":"608-615","source":"Crossref","is-referenced-by-count":11,"title":["SAVR versus TAVI: What about the Hemodynamic Performance? An In Vivo and In Vitro Analysis"],"prefix":"10.1055","volume":"68","author":[{"given":"Parwis Baradaran","family":"Rahmanian","sequence":"first","affiliation":[{"name":"Department of Cardiothoracic Surgery, Uniklinik Koln, Koln, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6941-7785","authenticated-orcid":false,"given":"Kaveh","family":"Eghbalzadeh","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery, Uniklinik Koln, Koln, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel","family":"Giese","sequence":"additional","affiliation":[{"name":"Department of Radiology, Uniklinik Koln, Koln, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elmar W.","family":"Kuhn","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery, Uniklinik Koln, Koln, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5810-8626","authenticated-orcid":false,"given":"Ilija","family":"Djordjevic","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery, Uniklinik Koln, Koln, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S\u00fcreyya","family":"Kaya","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery, Uniklinik Koln, Koln, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8490-5549","authenticated-orcid":false,"given":"Carolyn","family":"Weber","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery, Uniklinik Koln, Koln, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephan","family":"Baldus","sequence":"additional","affiliation":[{"name":"Department of Cardiology, University of Cologne, Heart Center, Cologne, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Navid","family":"Mader","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery, Uniklinik Koln, Koln, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thorsten C.W.","family":"Wahlers","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery, Uniklinik Koln, Koln, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2019,9,10]]},"reference":[{"issue":"10","key":"ref1","doi-asserted-by":"crossref","first-page":"967","DOI":"10.1056\/NEJMc1408396","article-title":"Transcatheter aortic-valve replacement with a self-expanding prosthesis","volume":"371","author":"D H Adams","year":"2014","journal-title":"N Engl J Med"},{"issue":"18","key":"ref2","doi-asserted-by":"crossref","first-page":"1686","DOI":"10.1056\/NEJMoa1200384","article-title":"Two-year outcomes after 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aortic valve replacement with the SAPIEN 3: a new balloon-expandable transcatheter heart valve","volume":"6","author":"R K Binder","year":"2013","journal-title":"JACC Cardiovasc Interv"},{"issue":"02","key":"ref17","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1161\/CIRCULATIONAHA.116.022797","article-title":"One-year clinical outcomes with SAPIEN 3 transcatheter aortic valve replacement in high-risk and inoperable patients with severe aortic stenosis","volume":"134","author":"H C Herrmann","year":"2016","journal-title":"Circulation"},{"issue":"15","key":"ref19","doi-asserted-by":"crossref","first-page":"1438","DOI":"10.1016\/j.jacc.2012.09.001","article-title":"Updated standardized endpoint definitions for transcatheter aortic valve implantation: the Valve Academic Research Consortium-2 consensus document","volume":"60","author":"A P Kappetein","year":"2012","journal-title":"J Am Coll 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Rahmanian","year":"2018","journal-title":"Ann Thorac Surg"},{"issue":"06","key":"ref29","doi-asserted-by":"crossref","first-page":"799","DOI":"10.1093\/icvts\/ivw052","article-title":"Conventional versus rapid-deployment aortic valve replacement: a single-centre comparison between the Edwards Magna valve and its rapid-deployment successor","volume":"22","author":"M Andreas","year":"2016","journal-title":"Interact Cardiovasc Thorac Surg"},{"issue":"05","key":"ref30","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1016\/j.jacc.2007.10.023","article-title":"Is it reasonable to treat all calcified stenotic aortic valves with a valved stent? Results from a human anatomic study in adults","volume":"51","author":"R Zegdi","year":"2008","journal-title":"J Am Coll Cardiol"},{"issue":"25","key":"ref31","first-page":"2514","article-title":"Comparison of transcatheter and surgical aortic valve replacement in severe aortic stenosis: a longitudinal study of echocardiography parameters in cohort A of the PARTNER trial (placement of aortic transcatheter valves)","volume":"61","author":"R T Hahn","year":"2013","journal-title":"J Am Coll Cardiol"},{"issue":"05","key":"ref32","doi-asserted-by":"crossref","first-page":"776","DOI":"10.1161\/CIRCIMAGING.112.000319","article-title":"Prosthesis-patient mismatch in bovine pericardial aortic valves: evaluation using 3 different modalities and associated medium-term outcomes","volume":"6","author":"S J Chacko","year":"2013","journal-title":"Circ Cardiovasc Imaging"},{"issue":"01","key":"ref33","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1016\/j.athoracsur.2007.08.024","article-title":"Permanent pacemaker implantation after isolated aortic valve replacement: incidence, indications, and predictors","volume":"85","author":"S Dawkins","year":"2008","journal-title":"Ann Thorac Surg"},{"issue":"05","key":"ref34","doi-asserted-by":"crossref","first-page":"1483","DOI":"10.1016\/j.athoracsur.2012.01.071","article-title":"Sutureless perceval aortic valve replacement: results of two European centers","volume":"93","author":"T A Folliguet","year":"2012","journal-title":"Ann Thorac Surg"},{"issue":"03","key":"ref35","doi-asserted-by":"crossref","first-page":"865","DOI":"10.1016\/j.jtcvs.2014.03.052","article-title":"Early and intermediate outcome after aortic valve replacement with a sutureless bioprosthesis: results of a multicenter study","volume":"148","author":"A S Rubino","year":"2014","journal-title":"J Thorac Cardiovasc Surg"},{"issue":"06","key":"ref36","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1016\/j.jacc.2012.03.054","article-title":"Impact of permanent pacemaker implantation on clinical outcome among patients undergoing transcatheter aortic valve implantation","volume":"60","author":"L Buellesfeld","year":"2012","journal-title":"J Am Coll Cardiol"},{"issue":"05","key":"ref37","doi-asserted-by":"crossref","first-page":"814","DOI":"10.1093\/icvts\/ivw226","article-title":"Do rapid deployment aortic valves improve outcomes compared with surgical aortic valve replacement?","volume":"23","author":"R A Davies","year":"2016","journal-title":"Interact Cardiovasc Thorac Surg"},{"issue":"03","key":"ref38","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1093\/ejcts\/ezv369","article-title":"Sutureless, rapid deployment valves and stented bioprosthesis in aortic valve replacement: recommendations of an International Expert Consensus Panel","volume":"49","author":"B Gersak","year":"2016","journal-title":"Eur J Cardiothorac Surg"}],"container-title":["The Thoracic and Cardiovascular Surgeon"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/s-0039-1695779.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,10,17]],"date-time":"2020-10-17T22:34:31Z","timestamp":1602974071000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/s-0039-1695779"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,9,10]]},"references-count":37,"journal-issue":{"issue":"07","published-online":{"date-parts":[[2020,10,17]]},"published-print":{"date-parts":[[2020,10]]}},"URL":"https:\/\/doi.org\/10.1055\/s-0039-1695779","relation":{},"ISSN":["0171-6425","1439-1902"],"issn-type":[{"type":"print","value":"0171-6425"},{"type":"electronic","value":"1439-1902"}],"subject":[],"published":{"date-parts":[[2019,9,10]]}}}