{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T13:48:49Z","timestamp":1680356929742},"reference-count":14,"publisher":"Georg Thieme Verlag KG","issue":"03","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Am J Perinatol"],"published-print":{"date-parts":[[2021,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n          Objective\u2003Given the paucity of contemporary data examining glucose challenge test (GCT), thresholds for gestational diabetes (GDM) screening in obese and overweight women, we sought to compare the sensitivity and testing characteristics of different screen positive GCT cut-offs in women with a prepregnancy body mass index (BMI) \u2265\u200925\u2009kg\/m2.<\/jats:p><jats:p>\n          Study Design\u2003This is a retrospective cohort study of obese and overweight women with singleton pregnancies who underwent GCT between 24 and 296\/7 weeks and had a value between 130 and 199\u2009mg\/dL necessitating a 3-hour glucose tolerance test (GTT). Exclusion criteria were pregestational diabetes mellitus, multigestation, use of diabetes medications, and bariatric surgery.<\/jats:p><jats:p>\n          Results\u2003Between August 2015 and January 2016, 19% (n\u2009=\u2009496) of women with a BMI \u2265\u200925\u2009kg\/m2 required a GTT to test for GDM, 27.8% (n\u2009=\u2009138) of whom were diagnosed with GDM. Mean age was 30 years, mean BMI\u2009=\u200931.6\u2009kg\/m2, and 30.4% were Hispanic. The 130\u2009mg\/dL threshold compared with 140\u2009mg\/dL was more sensitive (absolute increase: 11.3%, 95% confidence interval [CI]: 6.7\u201317%), but less specific (absolute decrease: 6.4%, 95% CI: 5.5\u20137.5%).<\/jats:p><jats:p>\n          Conclusion\u2003Shared decision making should be used to determine GCT cut-offs as some patients may prefer to undergo a GTT rather than miss a diagnosis of GDM.<\/jats:p>","DOI":"10.1055\/s-0039-1696674","type":"journal-article","created":{"date-parts":[[2019,9,6]],"date-time":"2019-09-06T23:17:31Z","timestamp":1567811851000},"page":"273-277","source":"Crossref","is-referenced-by-count":2,"title":["Comparing Glucose Challenge Test Screening Thresholds in Obese and Overweight Gravidas"],"prefix":"10.1055","volume":"38","author":[{"given":"Caitlin","family":"MacGregor","sequence":"additional","affiliation":[{"name":"University of Chicago Pritzker School of Medicine, Chicago, Illinois"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Phin","family":"Has","sequence":"additional","affiliation":[{"name":"Brown University, Providence, Rhode Island"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Deanna","family":"Nardella","sequence":"additional","affiliation":[{"name":"Brown University Warren Alpert Medical School, Providence, Rhode Island"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Erika","family":"Werner","sequence":"additional","affiliation":[{"name":"Brown University Warren Alpert Medical School, Providence, Rhode Island"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2019,9,6]]},"reference":[{"key":"ref1","first-page":"406","article-title":"Committee on Practice Bulletins\u2013Obstetrics","volume":"122","year":"2013","journal-title":"Obstet 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