{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T12:50:34Z","timestamp":1790859034269,"version":"4.1.0"},"reference-count":0,"publisher":"Georg Thieme Verlag KG","issue":"01","funder":[{"name":"NIH\/NCRR Colorado CTSI","award":["UL1 RR025780"],"award-info":[{"award-number":["UL1 RR025780"]}]},{"name":"National Institute on Child Health and Human Development","award":["5K12HD001271\u201318"],"award-info":[{"award-number":["5K12HD001271\u201318"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Am J Perinatol"],"published-print":{"date-parts":[[2020,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n          Objective\u2003We aimed to assess whether marijuana legalization was associated with a difference in prevalence of prenatal use or an increase in incidence of adverse perinatal outcomes.<\/jats:p><jats:p>\n          Study Design\u2003The present study is a retrospective cohort of September and October deliveries in the years 2012 through 2015 at a tertiary center in Colorado. Primary outcome of the study was use of marijuana, defined by self-report or biodetection. Secondary outcomes of the study included growth restriction, spontaneous preterm birth, stillbirth, preeclampsia, and neonatal or maternal death. Marijuana use prevalence was compared by year, and secondary outcomes between two periods, before and after the opening of the first recreational dispensary.<\/jats:p><jats:p>\n          Results\u2003A total of 2,392 pregnant women were included (1,165 before legalization and 1,227 after). More women used marijuana over the period of legalization (trend p\u2009=\u20090.01). Odds of marijuana use were higher after legalization versus before (adjusted odds ratio [aOR]\u2009=\u20091.8, 95% confidence interval [CI]: 1.2\u20132.6). Incidence of growth restriction was higher after legalization (2.9 vs. 5.1%, p\u2009=\u20090.0084). This difference persisted after adjustment for ethnicity and other drugs in multivariable modeling (aOR\u2009=\u20091.9, 95%CI: 1.2\u20133.0).<\/jats:p><jats:p>\n          Conclusion\u2003The prevalence of prenatal marijuana use increased over the time of legalization. Further investigation into the population impact of legalization on obstetrical outcomes is warranted given the observed increase in growth restriction.<\/jats:p>","DOI":"10.1055\/s-0039-1696719","type":"journal-article","created":{"date-parts":[[2019,9,6]],"date-time":"2019-09-06T23:17:31Z","timestamp":1567811851000},"page":"059-065","source":"Crossref","is-referenced-by-count":59,"title":["Impact of Marijuana Legalization on Prevalence of Maternal Marijuana Use and Perinatal Outcomes"],"prefix":"10.1055","volume":"37","author":[{"given":"Mayi","family":"Gnofam","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, University of Colorado Denver, Aurora, Colorado"},{"name":"Department of Obstetrics and Gynecology, Maison Blanche's Hospital, University of Reims, Champagne-Ardenne, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amanda A.","family":"Allshouse","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, University of Utah Health, Salt Lake City, Utah"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elaine H.","family":"Stickrath","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Denver Health and Hospital Authority, Denver, Colorado"},{"name":"University of Colorado School of Medicine, Aurora, Colorado"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Torri D.","family":"Metz","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, University of Utah Health, Salt Lake City, Utah"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2019,9,6]]},"container-title":["American Journal of Perinatology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/s-0039-1696719.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,1,6]],"date-time":"2020-01-06T23:36:27Z","timestamp":1578353787000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/s-0039-1696719"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,9,6]]},"references-count":0,"journal-issue":{"issue":"01","published-online":{"date-parts":[[2020,1,6]]},"published-print":{"date-parts":[[2020,1]]}},"URL":"https:\/\/doi.org\/10.1055\/s-0039-1696719","relation":{},"ISSN":["0735-1631","1098-8785"],"issn-type":[{"value":"0735-1631","type":"print"},{"value":"1098-8785","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,9,6]]}}}