{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,3]],"date-time":"2026-08-03T23:00:07Z","timestamp":1785798007938,"version":"3.56.0"},"reference-count":34,"publisher":"Georg Thieme Verlag KG","issue":"04","license":[{"start":{"date-parts":[[2020,1,9]],"date-time":"2020-01-09T00:00:00Z","timestamp":1578528000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100002322","name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior","doi-asserted-by":"crossref","award":["01-P-4346\/2015"],"award-info":[{"award-number":["01-P-4346\/2015"]}],"id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Funda\u00e7\u00e3o de Apoio \u00e0 Pesquisa do Estado de S\u00e3o Paulo","award":["889074"],"award-info":[{"award-number":["889074"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int Arch Otorhinolaryngol"],"published-print":{"date-parts":[[2020,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n          Introduction\u2003Otitis media (OM) is considered one of the most common reasons patients seek medical care in childhood. The fluctuating nature of hearing loss in cases of OM leads to irregular sound stimulation of the central auditory nervous system.<\/jats:p><jats:p>\n          Objectives\u2003To analyze the long-latency auditory-evoked potential (LLAEP) by verbal and nonverbal sounds in children with a history of OM in the first six years of life.<\/jats:p><jats:p>\n          Methods\u2003A total of 106 schoolchildren participated in the study, 55 females and 51 males, aged between 8 and 16 years, who were divided into 3 groups: the control group (CG), the bilateral experimental group (BEG), and the unilateral experimental group (UEG). All children underwent a complete audiological evaluation (audiometry, logoaudiometry and immitance testing) and an electrophysiological evaluation (LLAEP with toneburst stimulus \u2013 LLAEP-TB, and LLAEP with speech stimulus \u2013 LLAEP-S).<\/jats:p><jats:p>\n          Results\u2003Both study groups (BEG and UEG) presented a statistically lower performance (p\u2009&lt;\u20090.005) when compared with the CG regarding all of the electrophysiological tests with the prolongation of the latency values and decrease in the amplitude values: LLAEP-TB (BEG: latency - N1, P2, N2 [females] and P300, amplitude - N1 and P2), LLAEP-S (BEG: latency - P2 and N2 [females], amplitude - P2 \/UEG: latency - P2 and P300, amplitude: N1 and P2).<\/jats:p><jats:p>\n          Conclusion\u2003Children who had suffered secretory OM in the first six years of life and who had undergone myringotomy for the placement of a ventilation tube, either unilaterally or bilaterally, presented worse performance in their electrophysiological responses to verbal and nonverbal LLAEPs.<\/jats:p>","DOI":"10.1055\/s-0039-1697006","type":"journal-article","created":{"date-parts":[[2020,1,9]],"date-time":"2020-01-09T23:47:58Z","timestamp":1578613678000},"page":"e413-e422","source":"Crossref","is-referenced-by-count":6,"title":["Long-term Effects of Unilateral and Bilateral Otitis Media and Myringotomy on Long-Latency Verbal and Non-Verbal Auditory-Evoked Potentials"],"prefix":"10.1055","volume":"24","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3647-3999","authenticated-orcid":false,"given":"Milaine Dominici","family":"Sanfins","sequence":"additional","affiliation":[{"name":"Human Development Department, Faculdade de Ci\u00eancias M\u00e9dicas, Universidade Estadual de Campinas, Campinas, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caroline","family":"Donadon","sequence":"additional","affiliation":[{"name":"Human Development Department, Faculdade de Ci\u00eancias M\u00e9dicas, Universidade Estadual de Campinas, Campinas, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Let\u00edcia Reis","family":"Borges","sequence":"additional","affiliation":[{"name":"Human Development Department, Faculdade de Ci\u00eancias M\u00e9dicas, Universidade Estadual de Campinas, Campinas, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Piotr H.","family":"Skarzynski","sequence":"additional","affiliation":[{"name":"Department of Teleaudiology and Hearing Screening, World Hearing Center, Institute of Physiology and Pathology of Hearing, Warsaw\/Kajetany, Poland"},{"name":"Department of Heart Failure and Cardiac Rehabilitation, Warsaw, Poland"},{"name":"Department of Science and Development, Institute of Sensory Organs, Warsaw, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria Francisca","family":"Colella-Santos","sequence":"additional","affiliation":[{"name":"Human Development Department, Faculdade de Ci\u00eancias M\u00e9dicas, Universidade Estadual de Campinas, Campinas, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2020,1,9]]},"reference":[{"key":"ref1","first-page":"335","volume-title":"Otite media serosa\/secretora","author":"H Hungria","year":"1995"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1080\/000164800454026","article-title":"Lasting effects of otitis media with effusion on language skills and listening performance","volume":"543","author":"O Klausen","year":"2000","journal-title":"Acta Otolaryngol Suppl"},{"issue":"08","key":"ref4","doi-asserted-by":"crossref","first-page":"1412","DOI":"10.1162\/0898929042304796","article-title":"Sensitive periods in the development of the brain and behavior","volume":"16","author":"E I Knudsen","year":"2004","journal-title":"J Cogn 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