{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,24]],"date-time":"2026-04-24T10:15:36Z","timestamp":1777025736792,"version":"3.51.4"},"reference-count":0,"publisher":"Georg Thieme Verlag KG","issue":"12","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Thromb Haemost"],"published-print":{"date-parts":[[2019,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n          Background and Aim\u2003Post-discharge prophylaxis for venous thromboembolism (VTE) is a challenging issue in patients hospitalised in Internal Medicine Units (IMUs). The aim of this study was to evaluate the frequency and the factors associated with post-discharge prophylaxis for VTE in IMUs.<\/jats:p><jats:p>\n          Methods\u2003Multi-centre, retrospective study including consecutive patients who were admitted for any cause and discharged from an IMU.<\/jats:p><jats:p>\n          Results\u2003Overall, 3,740 patients (mean age 74.1\u2009\u00b1\u200915.7 years) were included in the study at 38 IMUs in Italy. At discharge, the percentage of patients receiving pharmacological thromboprophylaxis was 16.0% (20.1% after excluding patients treated with anticoagulants for indications other than VTE prophylaxis). At multivariable analysis, history of ischaemic stroke, hypomobility\u2009\u2265\u20097 days, central venous catheter,\u2009\u2265\u200910 versus\u2009\u2264\u20095 days of hospital stay, use of corticosteroids, cancer, history of falls, availability of a caregiver, infections and age were significantly associated with thromboprophylaxis, while an inverse correlation was observed with concomitant anti-platelet drugs and platelet count\u2009&lt;\u200970,000\/mm3. Patients with a Padua Prediction Score\u2009\u2265\u20094 versus\u2009&lt;\u20094 and with an IMPROVE bleeding score\u2009\u2265\u20097 versus\u2009&lt;\u20097 more frequently received prophylaxis at discharge (31.2% vs. 10.6%, p\u2009&lt;\u20090.0001, and 25.7% vs. 19.6%, p\u2009=\u20090.028, respectively).<\/jats:p><jats:p>\n          Conclusion\u2003In this study, one in five patients discharged from an Italian IMU received prophylaxis for VTE. The perceived thrombotic risk is significantly related to the use of prophylaxis.<\/jats:p>","DOI":"10.1055\/s-0039-1697661","type":"journal-article","created":{"date-parts":[[2019,10,21]],"date-time":"2019-10-21T23:00:16Z","timestamp":1571698816000},"page":"2043-2052","source":"Crossref","is-referenced-by-count":7,"title":["Prophylaxis of Venous Thromboembolism after Hospital Discharge in Internal Medicine: Findings from the Observational FADOI-NoTEVole Study"],"prefix":"10.1055","volume":"119","author":[{"given":"Alessandro","family":"Squizzato","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, University of Insubria, Varese, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giancarlo","family":"Agnelli","sequence":"additional","affiliation":[{"name":"Department of Internal and Cardiovascular Medicine-Stroke Unit, Hospital \u201cS. Maria della Misericordia,\u201d University of Perugia, Perugia, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mauro","family":"Campanini","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Hospital \u201cMaggiore della Carit\u00e0,\u201d Novara, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesco","family":"Dentali","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Hospital of Luino, ASST-Sette Laghi, University of Insubria, Varese, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesca","family":"Agnelli","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Erminio","family":"Bonizzoni","sequence":"additional","affiliation":[{"name":"Department of Clinical Science and Community, Section of Medical Statistics, Biometry and Epidemiology, Faculty of Medicine and Surgery, University of Milan, Milan, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alessandro","family":"Franco","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Hospital \u201cL. Parodi Delfino,\u201d Colleferro, Rome, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrea","family":"Gallo","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, University of Insubria, Varese, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gualberto","family":"Gussoni","sequence":"additional","affiliation":[{"name":"Department of Research, FADOI Foundation, Milan, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cinzia","family":"Nitti","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine, AOU Hospital, Ancona, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giuseppa","family":"Triolo","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Hospital \u201cVilla Sofia,\u201d Palermo, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonella","family":"Valerio","sequence":"additional","affiliation":[{"name":"Department of Research, FADOI Foundation, Milan, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesco","family":"Ventrella","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Hospital \u201cG. Tatarella\u201d- ASL-FG, Cerignola, FG, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrea","family":"Fontanella","sequence":"additional","affiliation":[{"name":"Department of Medical, Hospital \u201cBuon Consiglio-Fatebenefratelli,\u201d Naples, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"for the FADOI-NoTEVole Study Group","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2019,10,21]]},"container-title":["Thrombosis and Haemostasis"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/s-0039-1697661.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,12,5]],"date-time":"2019-12-05T23:59:06Z","timestamp":1575590346000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/s-0039-1697661"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,10,21]]},"references-count":0,"journal-issue":{"issue":"12","published-online":{"date-parts":[[2019,12,5]]},"published-print":{"date-parts":[[2019,12]]}},"URL":"https:\/\/doi.org\/10.1055\/s-0039-1697661","relation":{},"ISSN":["0340-6245","2567-689X"],"issn-type":[{"value":"0340-6245","type":"print"},{"value":"2567-689X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,10,21]]}}}